Intraventricular conduction in man studied with an endocardial electrode catheter mapping technique. Patients with normal QRS and right bundle branch block
| العنوان: | Intraventricular conduction in man studied with an endocardial electrode catheter mapping technique. Patients with normal QRS and right bundle branch block |
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| المؤلفون: | J C Shelburne, Joel H. Manchester, Bruce N. Goldreyer, E N Moore, John A. Kastor |
| المصدر: | Circulation. 51:786-796 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 1975. |
| سنة النشر: | 1975 |
| مصطلحات موضوعية: | Adult, Male, Bundle of His, Cardiac Catheterization, medicine.medical_specialty, Time Factors, Adolescent, Heart Ventricles, medicine.medical_treatment, Bundle-Branch Block, Action Potentials, Electrocardiography, QRS complex, Heart Conduction System, Physiology (medical), Internal medicine, Humans, Medicine, Ventricular outflow tract, Electrodes, Cardiac catheterization, Bundle branch block, medicine.diagnostic_test, business.industry, Middle Aged, Right bundle branch block, medicine.disease, Surgery, medicine.anatomical_structure, cardiovascular system, Cardiology, Female, Electrical conduction system of the heart, Cardiology and Cardiovascular Medicine, business |
| الوصف: | The sequence of intraventricular conduction has been studied in a total of 60 patients, 38 of whom had normal QRS morphology and 37 of whom had right bundle branch block (RBBB) either present continuously or produced as functional aberrant RBBB by the introduction of atrial premature depolarizations or by rapid atrial pacing. Activation times were measured by intracardiac electrode catheters positioned at the right ventricular inflow tract (RVIT), right ventricular apex (RVA), right ventricular outflow tract (RVOT), left ventricular apex (LVA) and left ventricular outflow tract (LVOT). The activation after beginning of QRS in milliseconds plus or minus 1 SD and the number of patients studied at each location were: RVIT--normal 23 plus or minus 13 (15 patients); RVIT-RBBB 49 plus or minus 16 (15 patients); RVA--normal 18 plus or minus 9 (28 patients); RVA-RBBB 54 plus or minus 16 (30 patients); RVOT--normal 40 plus or minus 10 (28 patients); RVOT-RBBB 78 plus or minus 21 (30 patients);LVA--normal 9 plus or minus 9 (18 patients); LVA-RBBB 6 plus or minus 10 (10 patients); LVOT--normal 45 plus or minus 13 (10 patients); LVOT-RBBB 32 plus or minus 9 (7 patients). Significant differences observed were: RVA-normal versus RVA-RBBB P smaller than 0.001; RVOT-RBBB P smaller than 0.001; RVA-normal versus LVA-normal P smaller than 0.005; LVA-normal versus LVA-RBBB NS, LVOT-normal versus LVOT-RBBB P smaller than 0.05. The LVOT change was unexpected and suggests changes in left ventricular depolarization may occur when right bundle branch block develops. In patients with RBBB the activation of the RVA (r equals 0.82) and of the RVOT (r equals 0.68) was directly related to the duration of QRS. Changes in activation time when RBBB was induced by rapid atrial pacing or by introduction of atrial premature depolarizations were: RVA (7 patients) 19 plus or minus 11 to 56 plus or minus 16 (P smaller than 0.001); RVOT (9 patients) 41 plus or minus 10 to 77 plus or minus 22 (P SMALLER THAN 0.001); LVA (5 patients) and LVOT (2 patients), small insignigicant changes. These data indicate that endocardial activation changes can be evaluated in the catheterization laboratory, that right ventricular conduction becomes slower in RBBB as a direct function of total QRS and that left ventricular conduction may be affected when RBBB develops. |
| تدمد: | 1524-4539 0009-7322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e573f3d5b6fc09db8f9f9fb3fb0ebeTest https://doi.org/10.1161/01.cir.51.5.786Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....06e573f3d5b6fc09db8f9f9fb3fb0ebe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15244539 00097322 |
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