Low-grade albuminuria is associated with hearing loss in non-diabetic US males
| العنوان: | Low-grade albuminuria is associated with hearing loss in non-diabetic US males |
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| المؤلفون: | Richard Salvi, Chia Hao Chang, Ming Hsui Tsai, Tang Chuan Wang, Chien Jen Chiu, Yi-Wen Liu, Chia-Der Lin, Ta-Yuan Chang, Chun Jung Juan |
| المصدر: | Medicine |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Blood Glucose, Male, Cross-sectional study, Comorbidity, Severity of Illness Index, 0302 clinical medicine, Reference Values, 030212 general & internal medicine, glomerular filtration rate, education.field_of_study, diabetes, Incidence, Incidence (epidemiology), National Health and Nutritional Examination Survey (NHANES), General Medicine, Middle Aged, Nutrition Surveys, 030220 oncology & carcinogenesis, medicine.symptom, Risk assessment, Research Article, Adult, medicine.medical_specialty, National Health and Nutrition Examination Survey, Hearing loss, Population, Observational Study, Urinalysis, albumin-to-creatinine ratio, Risk Assessment, 03 medical and health sciences, Age Distribution, Audiometry, Internal medicine, Diabetes Mellitus, medicine, Albuminuria, Humans, Hearing Loss, education, Aged, business.industry, medicine.disease, United States, Cross-Sectional Studies, Multivariate Analysis, Linear Models, business |
| الوصف: | High levels of albuminuria have been demonstrated to associate with hearing loss in non-diabetic people, while the clinical impact of low-grade albuminuria has attracted less attention. This cross-sectional population-based study aimed to examine whether hearing loss in non-diabetic United States (US) adults is independently associated with low-grade albuminuria or reduced estimated glomeruli filtration rate (eGFR). A total of 2518 participants aged 20 to 69 years were selected from the US National Health and Nutritional Examination Survey database. Participants with diabetes or high-grade albuminuria were excluded. Hearing loss was assessed using low-frequency pure-tone average (LFPTA) thresholds (0.5, 1.0, 2.0 kHz) and high-frequency pure-tone average (HFPTA) thresholds (3.0, 4.0, 6.0, 8.0 kHz). Logistic and linear regression analyses were used to evaluate associations between renal function indicators and hearing loss. The median age of included participants was 37.4 years, and 55% of them were female. Multivariate analysis revealed that participants with urinary albumin-to-creatinine ratio (UACR) in the highest tertile had a significantly higher risk of hearing loss (OR, 1.79; 95% CI, 1.01–3.19) and higher HFPTA thresholds (β: 2.23; SE: 0.77). Participants with eGFR |
| تدمد: | 1536-5964 0025-7974 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d16621e6dc4121e6fd70d97d7c7a02Test https://doi.org/10.1097/md.0000000000019284Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b7d16621e6dc4121e6fd70d97d7c7a02 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15365964 00257974 |
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