Understanding the changes of cone reflectance in adaptive optics flood illumination retinal images over three years
| العنوان: | Understanding the changes of cone reflectance in adaptive optics flood illumination retinal images over three years |
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| المؤلفون: | Marco Lombardo, Letizia Mariotti, Nicholas Devaney, Giuseppe Lombardo |
| المساهمون: | ~ |
| المصدر: | Biomedical optics express 7 (2016): 2807–2822. doi:10.1364/BOE.7.002807 info:cnr-pdr/source/autori:Mariotti, Letizia; Devaney, Nicholas; Lombardo, Giuseppe; Lombardo, Marco/titolo:Understanding the changes of cone reflectance in adaptive optics flood illumination retinal images over three years/doi:10.1364%2FBOE.7.002807/rivista:Biomedical optics express/anno:2016/pagina_da:2807/pagina_a:2822/intervallo_pagine:2807–2822/volume:7 |
| بيانات النشر: | Optical Society of America, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | receptor optics, genetic structures, Image quality, 01 natural sciences, in-vivo, Pupil, Article, 010309 optics, 03 medical and health sciences, 0302 clinical medicine, Optics, Optical coherence tomography, registration, In vivo, 0103 physical sciences, medicine, Coherence (signal processing), Adaptive optics, Tomography, coherence tomography, Retina, density, medicine.diagnostic_test, business.industry, Physics, parafoveal cones, Ranging, photoreceptors, Density estimation, sensitivity, eye diseases, Atomic and Molecular Physics, and Optics, medicine.anatomical_structure, Visual optics, 030221 ophthalmology & optometry, Medical and biological imaging, sense organs, business, Coherence, Geology, Biotechnology |
| الوصف: | Although there is increasing interest in the investigation of cone reflectance variability, little is understood about its characteristics over long time scales. Cone detection and its automation is now becoming a fundamental step in the assessment and monitoring of the health of the retina and in the understanding of the photoreceptor physiology. In this work we provide an insight into the cone reflectance variability over time scales ranging from minutes to three years on the same eye, and for large areas of the retina (>= 2.0 x 2.0 degrees) at two different retinal eccentricities using a commercial adaptive optics (AO) flood illumination retinal camera. We observed that the difference in reflectance observed in the cones increases with the time separation between the data acquisitions and this may have a negative impact on algorithms attempting to track cones over time. In addition, we determined that displacements of the light source within 0.35 mm of the pupil center, which is the farthest location from the pupil center used by operators of the AO camera to acquire high-quality images of the cone mosaic in clinical studies, does not significantly affect the cone detection and density estimation. (C) 2016 Optical Society of America Research for this work was supported by the Irish Research Council (GOIPG/2013/775), the National Framework Program for Research and Innovation PON (grant n. 01 00110), the Italian Ministry of Health (grant 5×1000) and Fondazione Roma. peer-reviewed |
| وصف الملف: | application/pdf |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e40a6a318ee4b3fb6f1fdc223396edbTest https://europepmc.org/articles/PMC4948632Test/ |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5e40a6a318ee4b3fb6f1fdc223396edb |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |