Improving Memory in Patients with Epilepsy: Considering the Impact of Anti-Epileptic Drugs, Low Mood and/or Surgery on Memory Training Program Outcomes
التفاصيل البيبلوغرافية
العنوان:
Improving Memory in Patients with Epilepsy: Considering the Impact of Anti-Epileptic Drugs, Low Mood and/or Surgery on Memory Training Program Outcomes
Aim: To determine whether epilepsy treatments (number of antiepileptic drugs and surgical history) and/or depressed mood would influence the ability to benefit from memory training of outpatients with epilepsy who participated in a group-based, six-week, Memory Training Program. We also investigated the relationships between symptoms of depression, performance on a new objective measure of association memory and subjective memory ratings. Method: Forty-seven adults with epilepsy and memory complaints completed the training with pre- and posttraining assessments. Scores included (1) number correct on a new Identity Association Memory Test; (2) subjective self-rating of memory function; (3) number of reported strategies used for memory support. Two way (Group x Time) Repeated Measures Analyses of Variance were used to look for differences on the association-learning task. Pearson correlation analyses were used to examine the relationships between number of anti-epileptic drugs, subjective memory ratings, and presence of depression and objective memory scores. Results: Repeated measures ANOVAs demonstrated that training resulted in significant improvements of the total score on the Association Memory Test regardless of number of antiepileptic drugs (F=6.5,p=.01), surgical status (F=6,p=.02) or mood (F=7.4,p
