دورية أكاديمية
Current Meningococcal Vaccines: Advantages and Disadvantages and New Challenges
| العنوان: | Current Meningococcal Vaccines: Advantages and Disadvantages and New Challenges |
|---|---|
| المؤلفون: | N. N. Kostyukova, V. A. Bekhalo |
| المصدر: | Эпидемиология и вакцинопрофилактика, Vol 15, Iss 4, Pp 64-73 (2016) |
| بيانات النشر: | Numikom LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | менингококковые вакцины, полисахаридные вакцины, конъюгированные вакцины, генно-инженерные вакцины, обратная вакцинология, the meningococcal vaccines, the polysaccharide vaccines, the conjugated vaccines, the vesicle vaccines, the geneticengineering vaccines, reverse vaccinology, Epistemology. Theory of knowledge, BD143-237 |
| الوصف: | The article reviews and analyses the vaccines against invasive meningococcal disease, widely used in practice since 70s-80s of the last century, as well as newly developed ones, the efficacy of which is not completely clear yet. The advantages and disadvantages of polysaccharide and glycoprotein vaccines against meningococci of serogroups A, C, Y, W135 and of protein «vesicle» and geneticengineering vaccines based on «reverse vaccinology» against serogroup B are discussed. Some options for composition of future vaccines under development are presented. Briefly the meningococcal vaccines used in Russia are described. Among the most important immediate tasks discussed are: the study of the duration and intensity of protection after immunization with conjugate vaccines; the development and subsequent trials of a vaccine against serogroup X; further study and improvement of vaccines against serogroup B, as well as the creation of a single vaccine product that protects against all antigenic variants of Neisseria meningitidis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 2073-3046 2619-0494 |
| العلاقة: | https://www.epidemvac.ru/jour/article/view/184Test; https://doaj.org/toc/2073-3046Test; https://doaj.org/toc/2619-0494Test |
| DOI: | 10.31631/2073-3046-2016-15-4-64-73 |
| الوصول الحر: | https://doaj.org/article/4512f14c20644bbe87df4ac335070aa7Test |
| رقم الانضمام: | edsdoj.4512f14c20644bbe87df4ac335070aa7 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 20733046 26190494 |
|---|---|
| DOI: | 10.31631/2073-3046-2016-15-4-64-73 |