دورية أكاديمية

Ribavirin for Chronic Hepatitis E Virus Infection in Transplant Recipients.

التفاصيل البيبلوغرافية
العنوان: Ribavirin for Chronic Hepatitis E Virus Infection in Transplant Recipients.
المؤلفون: Kamar, Nassim1,2,3,4 kamar.n@chu-toulouse.fr, Izopet, Jacques3,4,5,6, Tripon, Simona7, Bismuth, Michael8, Hillaire, Sophie9, Dumortier, Jérôme10, Radenne, Sylvie11,12, Coilly, Audrey13,14, Garrigue, Valérie15, D'Alteroche, Louis16, Buchler, Matthias17, Couzi, Lionel18, Lebray, Pascal19, Dharancy, Sebastien20,21, Minello, Anne22, Hourmant, Maryvonne23, Roque-Afonso, Anne-Marie13,14, Abravanel, Florence3,4,5,6, Pol, Stanislas7,24, Rostaing, Lionel2,3,4
المصدر: New England Journal of Medicine. 3/20/2014, Vol. 370 Issue 12, p1111-1120. 10p.
مصطلحات موضوعية: *RIBAVIRIN, *HEPATITIS E, *TRANSPLANTATION of organs, tissues, etc., *DRUG efficacy, *VIREMIA, *PATIENTS, *THERAPEUTICS
مستخلص: The article discusses a study on the drug ribavirin's safety as monotherapy for hepatitis E virus (HEV) infection in solid-organ transplant patients in France. Topics addressed include the suitability of a three-month treatment course for most patients, HEV clearance in the majority of patients, and the recurrence of HEV replication in several patients after treatment was halted. Also mentioned are observations of sustained virologic responses and anemia as the main side effect.
قاعدة البيانات: Academic Search Index
الوصف
تدمد:00284793
DOI:10.1056/NEJMoa1215246