Origin and spread of human mitochondrial DNA haplogroup U7
| العنوان: | Origin and spread of human mitochondrial DNA haplogroup U7 |
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| المؤلفون: | Deepankar Pratap Singh, Massoud Houshmand, Periyasamy Govindaraj, I. A. Kutuev, Duran Ustek, Erika Tamm, Kumarasamy Thangaraj, Levon Yepiskoposyan, Shirin Farjadian, Antonio Torroni, Phillip Endicott, Vijay Kumar Singh, Monika Karmin, Ekta Rai, Ornella Semino, Marta D. Costa, Erwan Pennarun, Ajai Kumar Pathak, Vladimir Orekhov, S. S. Litvinov, Francesca Gandini, Larissa Damba, Ardeshir Bahmanimehr, Hovhannes Sahakyan, Katrin Kaldma, Alessandro Achilli, Kristiina Tambets, Maere Reidla, Doron M. Behar, Ene Metspalu, Kalliopi I. Pappa, Viktor Černý, Vladislava Gusar, Elena Grechanina, Pedro Soares, Manvendra K. Singh, Richard Villems, Verónica Fernandes, Mannis van Oven, Anna Olivieri, Niraj Rai, Mait Metspalu, Toomas Kivisild, Ugo A. Perego, Mikhail Voevoda, Amirtharaj Francis, Jelena Šarac, Rakesh Tamang, Lovorka Barać Lauc, Gyaneshwer Chaubey, Elza Khusnutdinova, Lalji Singh, Maya Simionescu, Indu Sharma, Swarkar Sharma, Martin B. Richards, Tena Šarić, M. V. Golubenko, Hrant Hovhannisyan, Alla G. Reddy, Natalia Ekomasova Trofimova, Tuuli Reisberg, Nicholas P. Anagnou, Nadia Al-Zahery, S. A. Borinskaya, Varun Sharma, Mohammad Hossein Sanati, Monica A. Schauer, Helle Viivi Tolk, Jüri Parik, Marina Bermisheva, Alena Kushniarevich, Emmanuel Michalodimitrakis, Pavao Rudan, Baharak Hooshiar Kashani, Luísa Pereira, Hulya Azakli, Svjetlana Cvjetan, Zaruhi Khachatryan |
| المساهمون: | Universidade do Minho |
| المصدر: | Scientific reports, 7 Scientific Reports Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| بيانات النشر: | Nature Research, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0301 basic medicine, Haplogroup M, Haplogroup H, Human Y-chromosome DNA haplogroup, Haplogroup G-P303, Haplogroup U, DNA, Mitochondrial, Article, Results and Discussion, Evolution, Molecular, 03 medical and health sciences, QH301, Phénomènes atmosphériques, Humans, Haplogroup D-M15, QH426, Phylogeny, Multidisciplinary, Science & Technology, Geography, Bayes Theorem, Haplogroup L3, mtDNA, mitogenome, U7, origin, spread, 030104 developmental biology, Haplotypes, Mutation, Ethnology, Human mitochondrial DNA haplogroup |
| الوصف: | Human mitochondrial DNA haplogroup U is among the initial maternal founders in Southwest Asia and Europe and one that best indicates matrilineal genetic continuity between late Pleistocene hunter-gatherer groups and present-day populations of Europe. While most haplogroup U subclades are older than 30 thousand years, the comparatively recent coalescence time of the extant variation of haplogroup U7 (∼16-19 thousand years ago) suggests that its current distribution is the consequence of more recent dispersal events, despite its wide geographical range across Europe, the Near East and South Asia. Here we report 267 new U7 mitogenomes that - analysed alongside 100 published ones - enable us to discern at least two distinct temporal phases of dispersal, both of which most likely emanated from the Near East. The earlier one began prior to the Holocene (∼11.5 thousand years ago) towards South Asia, while the later dispersal took place more recently towards Mediterranean Europe during the Neolithic (∼8 thousand years ago). These findings imply that the carriers of haplogroup U7 spread to South Asia and Europe before the suggested Bronze Age expansion of Indo-European languages from the Pontic-Caspian Steppe region. 0 SCOPUS: ar.j info:eu-repo/semantics/published |
| وصف الملف: | application/pdf; 1 full-text file(s): application/pdf |
| اللغة: | English |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4240a88fa7e9c9538deb7ee485896979Test https://hdl.handle.net/1822/63890Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....4240a88fa7e9c9538deb7ee485896979 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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