دورية أكاديمية
Prognostic value of hypoalbuminemia for adverse outcomes in patients with rheumatic heart disease undergoing valve replacement surgery
| العنوان: | Prognostic value of hypoalbuminemia for adverse outcomes in patients with rheumatic heart disease undergoing valve replacement surgery |
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| المؤلفون: | Wei, Xue-biao, Jiang, Lei, Liu, Yuan-hui, Feng, Du, He, Peng-cheng, Chen, Ji-yan, Yu, Dan-qing, Tan, Ning |
| بيانات النشر: | Nature Publishing Group UK |
| سنة النشر: | 2017 |
| المجموعة: | Harvard University: DASH - Digital Access to Scholarship at Harvard |
| الوصف: | High-risk patients with rheumatic heart disease (RHD) who were undergoing valve replacement surgery (VRS) were not identified entirely. This study included 1782 consecutive patients with RHD who were undergoing VRS to explore the relationship between hypoalbuminemia and adverse outcomes and to confirm whether hypoalbuminemia plays a role in risk evaluation. A total of 27.3% of the RHD patients had hypoalbuminemia. In-hospital deaths were significantly higher in the hypoalbuminemic group than in the non-hypoalbuminemic group (6.6% vs 3.1%, P = 0.001). Hypoalbuminemia was an independent predictor of in-hospital death (OR = 1.89, P = 0.014), even after adjusting for the Euro score. The addition of hypoalbuminemia to Euro score enhanced net reclassification improvement (0.346 for in-hospital death, P = 0.004; 0.306 for 1-year death, p = 0.005). A Kaplan-Meier curve analysis revealed that the cumulative rate of 1-year mortality after the operation was higher in patients with a new Euro score ≥6. These findings indicated that hypoalbuminemia was an independent risk factor for in-hospital and 1-year mortality after VRS in patients with RHD, which might have additive prognostic value to Euro score. ; Version of Record |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434000/pdfTest/; Scientific Reports; Wei, Xue-biao, Lei Jiang, Yuan-hui Liu, Du Feng, Peng-cheng He, Ji-yan Chen, Dan-qing Yu, and Ning Tan. 2017. “Prognostic value of hypoalbuminemia for adverse outcomes in patients with rheumatic heart disease undergoing valve replacement surgery.” Scientific Reports 7 (1): 1958. doi:10.1038/s41598-017-02185-2. http://dx.doi.org/10.1038/s41598-017-02185-2Test.; http://nrs.harvard.edu/urn-3:HUL.InstRepos:33029901Test |
| DOI: | 10.1038/s41598-017-02185-2 |
| الإتاحة: | https://doi.org/10.1038/s41598-017-02185-2Test http://nrs.harvard.edu/urn-3:HUL.InstRepos:33029901Test |
| رقم الانضمام: | edsbas.577274E4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41598-017-02185-2 |
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