Dual-Energy X-Ray Absorptiometry Compared to Computed Tomography for Visceral Adiposity Assessment Among Gastrointestinal and Pancreatic Cancer Survivors
| العنوان: | Dual-Energy X-Ray Absorptiometry Compared to Computed Tomography for Visceral Adiposity Assessment Among Gastrointestinal and Pancreatic Cancer Survivors |
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| المؤلفون: | Ann H. Klopp, Naveen Garg, Aaroh M. Parikh, David R. Fogelman, Adriana M. Coletta, Karen Basen-Engquist, Yisheng Li |
| المصدر: | Scientific Reports Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019) |
| بيانات النشر: | Nature Publishing Group UK, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Male, medicine.medical_specialty, Population, lcsh:Medicine, Computed tomography, Intra-Abdominal Fat, Article, 03 medical and health sciences, Gastrointestinal cancer, 0302 clinical medicine, Absorptiometry, Photon, Cancer Survivors, Pancreatic cancer, medicine, Humans, education, lcsh:Science, Pelvis, Dual-energy X-ray absorptiometry, Gastrointestinal Neoplasms, education.field_of_study, Multidisciplinary, medicine.diagnostic_test, business.industry, lcsh:R, Cancer, nutritional and metabolic diseases, Middle Aged, medicine.disease, 3. Good health, Pancreatic Neoplasms, 030104 developmental biology, medicine.anatomical_structure, Homogeneous, lcsh:Q, Cancer imaging, Female, Tomography, Radiology, business, Tomography, X-Ray Computed, human activities, 030217 neurology & neurosurgery |
| الوصف: | Dual-energy x-ray absorptiometry (DXA) for visceral adipose tissue (VAT) assessment is used as an alternative to computed tomography (CT) for research purposes in apparently healthy and clinical populations. It is unknown whether DXA is comparable to CT among cancer survivors, especially in cases where VAT assessment may be affected by treatment history and side effects and become more challenging to assess, such as a history of surgical gastrointestinal resection and/or ascites. The purpose of this study was to determine the level of agreement between DXA and CT when assessing VAT area and volume among cancer survivors. One hundred Gastrointestinal and pancreatic cancer survivors underwent abdominal and pelvis CT and whole-body DXA within 48 hours. Bland-Altman analysis revealed that in women and men, DXA VAT-area estimates were larger and smaller, respectively, and was consistently smaller in estimates for VAT-volume. Correlations from linear regression analysis revealed statistically significant positive correlations between measurement methods. Overall, while DXA VAT estimates are highly correlated with CT VAT estimates, DXA estimates show substantial bias which indicates the two methods are not interchangeable in this population. Further research is warranted with a larger, more homogeneous sample to develop better estimates of the bias. |
| اللغة: | English |
| تدمد: | 2045-2322 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20116f0eda96c43bb0293aacf17297d9Test http://europepmc.org/articles/PMC6687706Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....20116f0eda96c43bb0293aacf17297d9 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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