نتائج البحث

1

Genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in Type 1 Diabetes from an admixed Brazilian population

المؤلفون: Vandilson Pinheiro Rodrigues, Sabrina da Silva Pereira Damianse, Dayse A. Silva, Viviane Chaves de Carvalho Rocha, Marília B. Gomes, Manuel dos Santos Faria, Luís Cristóvão Porto, Rossana Santiago de Sousa Azulay, Paulo Carvalho, Marcelo Magalhães, Maria da Gloria Tavares, Gilvan Cortês Nascimento, Roberta Maria Duailibe Ferreira Reis

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, Adult, Genetic Markers, Male, Genetic genealogy, Science, Population, 030209 endocrinology & metabolism, Human leukocyte antigen, Biology, Y chromosome, Article, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, immune system diseases, HLA Antigens, Genotype, medicine, Genetics, Humans, Genetic Predisposition to Disease, Allele, education, skin and connective tissue diseases, Phylogeny, Type 1 diabetes, education.field_of_study, Principal Component Analysis, Multidisciplinary, Chromosomes, Human, Y, Geography, Heterozygote advantage, Gene Pool, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Haplotypes, Case-Control Studies, Medicine, Female, Brazil

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c6e9718178e5b329839e3403e5b337Test
http://europepmc.org/articles/PMC8266844Test

2

Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population

المؤلفون: Qi zhu Hong, Jing Zheng, Xin ting Pan, Xian-E Peng, Xiao Ling Cai, Hui quan Li, Jian Hui Yan, He wei Peng, Bing bing Chen

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, China, medicine.medical_specialty, DNA Copy Number Variations, Science, Carboxylesterase 1, Diseases, Disease, Biology, Logistic regression, Risk Assessment, Gastroenterology, Article, law.invention, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Asian People, Liver Function Tests, Non-alcoholic Fatty Liver Disease, law, Internal medicine, medicine, TaqMan, Genetics, Humans, Genetic Predisposition to Disease, Copy-number variation, Polymerase chain reaction, Aged, Multidisciplinary, Cholesterol, Fatty liver, Middle Aged, medicine.disease, 030104 developmental biology, chemistry, Case-Control Studies, Medicine, Female, 030211 gastroenterology & hepatology, Carboxylic Ester Hydrolases, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8183a085da560b2567dd6e49879b680Test
http://europepmc.org/articles/PMC8263572Test

3

Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis

المؤلفون: Shuo Li, Edward B. Garon, Frank Alber, Xiaohui Ni, Steven M. Dubinett, Yonggang Zhou, Wing Hung Wong, Weihua Zeng, Mary L. Stackpole, Wenyuan Li, Xianghong Jasmine Zhou, Vatche G. Agopian, Zuyang Yuan, Zorawar S. Noor

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature communications, vol 12, iss 1

مصطلحات موضوعية: 0301 basic medicine, Male, Statistical methods, medicine.medical_treatment, Biopsy, DNA Mutational Analysis, Programmed Cell Death 1 Receptor, Drug Resistance, General Physics and Astronomy, Datasets as Topic, Circulating Tumor DNA, 0302 clinical medicine, Neoplasms, Monoclonal, Cancer genomics, Humanized, Immune Checkpoint Inhibitors, Exome sequencing, Cancer, screening and diagnosis, Tumor, Multidisciplinary, Single Nucleotide, Middle Aged, Prognosis, Progression-Free Survival, Detection, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Biomarker (medicine), Female, 4.2 Evaluation of markers and technologies, Adult, Science, Sequencing data, Computational biology, Antibodies, Monoclonal, Humanized, Polymorphism, Single Nucleotide, Sensitivity and Specificity, Antibodies, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Exome Sequencing, Genetics, medicine, Biomarkers, Tumor, Humans, Computer Simulation, Genetic Testing, Progression-free survival, Polymorphism, business.industry, Human Genome, General Chemistry, Patient data, Immunotherapy, medicine.disease, 4.1 Discovery and preclinical testing of markers and technologies, Computational biology and bioinformatics, Good Health and Well Being, 030104 developmental biology, Drug Resistance, Neoplasm, Mutation, Neoplasm, business, Biomarkers, Software

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78118c6a69c156d0987bbf4bddc8d970Test
http://europepmc.org/articles/PMC8263778Test

4

MicroRNA-513b-5p targets COL1A1 and COL1A2 associated with the formation and rupture of intracranial aneurysm

المؤلفون: Qiong Cheng, Zheng Zheng, Yan Chen, Yin-zhou Wang, Yongkun Li

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, Adult, Male, Programmed cell death, MMP3, congenital, hereditary, and neonatal diseases and abnormalities, Cell biology, MMP2, Molecular biology, Science, Myocytes, Smooth Muscle, Gene Expression, macromolecular substances, MMP9, Aneurysm, Ruptured, Article, Collagen Type I, Cell Line, 03 medical and health sciences, Young Adult, 0302 clinical medicine, microRNA, Genetics, Gene silencing, Humans, skin and connective tissue diseases, Genetic Association Studies, Aged, Aged, 80 and over, Multidisciplinary, integumentary system, Cell growth, Chemistry, Intracranial Aneurysm, Middle Aged, Collagen Type I, alpha 1 Chain, MicroRNAs, 030104 developmental biology, Apoptosis, Cancer research, Medicine, Female, 030217 neurology & neurosurgery, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e176c27698e923f56beab38ba11573ecTest
http://europepmc.org/articles/PMC8295310Test

5

Lipopolysaccharide stimulation test on cultured PBMCs assists the discrimination of cryopyrin-associated periodic syndrome from systemic juvenile idiopathic arthritis

المؤلفون: Jing-Long Huang, Ying-Ming Chiu, Huang-Yu Yang, Chao-Yi Wu, Wen-Lang Fan, Wen-I Lee

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

مصطلحات موضوعية: 0301 basic medicine, Adult, Lipopolysaccharides, Male, Lipopolysaccharide, Inflammasomes, Science, Interleukin-1beta, Arthritis, Stimulation, Paediatric research, Peripheral blood mononuclear cell, Sensitivity and Specificity, Article, Proinflammatory cytokine, Diagnosis, Differential, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Humans, Child, Immunological disorders, Cells, Cultured, 030203 arthritis & rheumatology, Multidisciplinary, business.industry, Caspase 1, Interleukin-18, Cryopyrin-associated periodic syndrome, Inflammasome, medicine.disease, Arthritis, Juvenile, Cryopyrin-Associated Periodic Syndromes, 030104 developmental biology, chemistry, Macrophage activation syndrome, Immunology, Leukocytes, Mononuclear, Cytokines, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295e7845a02cdffedf373dfd172748f6Test
http://europepmc.org/articles/PMC8185076Test

6

Mucosal ribosomal stress-induced PRDM1 promotes chemoresistance via stemness regulation

المؤلفون: Yuseok Moon, Juil Kim

المصدر: Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Colorectal cancer, medicine.medical_treatment, Medicine (miscellaneous), Apoptosis, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Transcriptional regulation, Tumor Cells, Cultured, Biology (General), Intestinal Mucosa, Aged, 80 and over, Mice, Inbred BALB C, Middle Aged, Prognosis, Gene Expression Regulation, Neoplastic, Survival Rate, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Female, General Agricultural and Biological Sciences, Colorectal Neoplasms, Reprogramming, Signal Transduction, Cancer microenvironment, Adult, QH301-705.5, Mice, Nude, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Stress, Physiological, PRDM1, medicine, Biomarkers, Tumor, Animals, Humans, Transcription factor, Aged, Cell Proliferation, Growth factor, Ribosomal RNA, medicine.disease, Xenograft Model Antitumor Assays, Mice, Inbred C57BL, 030104 developmental biology, Pharmacodynamics, Drug Resistance, Neoplasm, Cancer cell, Cancer research, Positive Regulatory Domain I-Binding Factor 1, Ribosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54587c360a9ab6470f2c24a36d5b3d1cTest
http://europepmc.org/articles/PMC8110964Test

7

HLA class II genotyping of admixed Brazilian patients with type 1 diabetes according to self-reported color/race in a nationwide study

المؤلفون: Deborah Conte Santos, Luiza Harcar Muniz, Luís Cristóvão Porto, Dayse A. Silva, Romulo Vianna Oliveira, Bianca Senger Vasconcelos Barros, Laura G. N. Mello, Leonardo Hanhoerderster, Marília B. Gomes, Marcela Haas Pizarro, Danielle Secco

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, Adult, Male, endocrine system diseases, Genotyping Techniques, Population, Genes, MHC Class II, Ethnic group, lcsh:Medicine, 030209 endocrinology & metabolism, Human leukocyte antigen, Biology, Article, 03 medical and health sciences, Race (biology), 0302 clinical medicine, immune system diseases, Risk Factors, medicine, Humans, Clinical genetics, Allele, lcsh:Science, education, skin and connective tissue diseases, Genotyping, Alleles, Type 1 diabetes, education.field_of_study, Multidisciplinary, lcsh:R, Haplotype, Racial Groups, nutritional and metabolic diseases, Endocrine system and metabolic diseases, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Haplotypes, lcsh:Q, Female, Self Report, Brazil, Demography

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01db864983ea8f0af80ed1edc1100499Test
http://europepmc.org/articles/PMC7170860Test

8

Enhanced STAT3 phosphorylation and PD-L1 expression in myeloid dendritic cells indicate impaired IL-27Ralpha signaling in type 1 diabetes

المؤلفون: Zdeněk Šumník, L. Sojka, Jana Kayserova, Irena Zentsova, Petra Vrabcova, I. Richtrova, Zuzana Parackova, Anna Sediva, Katerina Stechova

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, STAT3 Transcription Factor, Myeloid, lcsh:Medicine, Inflammation, Biology, stat, Article, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, medicine, Cytotoxic T cell, Humans, Interleukin 27, Phosphorylation, lcsh:Science, STAT3, Aged, Oligonucleotide Array Sequence Analysis, Multidisciplinary, Interleukins, Gene Expression Profiling, lcsh:R, JAK-STAT signaling pathway, Dendritic Cells, Receptors, Interleukin, Middle Aged, 030104 developmental biology, medicine.anatomical_structure, Type 1 diabetes, Diabetes Mellitus, Type 1, Case-Control Studies, biology.protein, Cancer research, lcsh:Q, Female, medicine.symptom, Signal transduction, 030215 immunology, Cell signalling, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f424f9a0841df799c6520ecbe237b2a3Test
http://europepmc.org/articles/PMC6965661Test

9

Balance Impairments in Patients with Human T-Cell Lymphotropic Virus Type 1 Infection

المؤلفون: Givago da Silva Souza, Tatiana Generoso Campos Pinho Barroso, Marília Brasil Xavier, Ghislain Saunier, Beatriz H. Baldez Vasconcelos, Rita Catarina Medeiros Sousa, Bianca Callegari, Kelly Helorany Alves Costa

المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, lcsh:Medicine, Asymptomatic, Article, 03 medical and health sciences, Myelopathy, 0302 clinical medicine, immune system diseases, Internal medicine, hemic and lymphatic diseases, Tropical spastic paraparesis, Postural Balance, medicine, Humans, Spasticity, Human T cell lymphotropic virus type 1, Motor neuron disease, lcsh:Science, Asymptomatic Infections, Balance (ability), Human T-lymphotropic virus 1, Multidisciplinary, business.industry, lcsh:R, Case-control study, virus diseases, Middle Aged, medicine.disease, HTLV-I Infections, Healthy Volunteers, Paraparesis, Tropical Spastic, 030104 developmental biology, Viral infection, Case-Control Studies, lcsh:Q, Female, medicine.symptom, business, 030217 neurology & neurosurgery, Central nervous system infections

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3145c94668f9544b477fbdeed7c6250aTest
http://europepmc.org/articles/PMC6685957Test

10

A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine

المصدر: British Journal of Cancer
British journal of cancer, vol. 118, no. 10, pp. 1302-1312

مصطلحات موضوعية: 0301 basic medicine, Neuroblastoma RAS viral oncogene homolog, Adult, Male, Cancer Research, Programmed Cell Death 1 Receptor, Adenocarcinoma/genetics, Adenocarcinoma/pathology, Aged, Aged, 80 and over, Anus Neoplasms/genetics, Anus Neoplasms/pathology, B7-H1 Antigen/genetics, ErbB Receptors/genetics, Female, Gene Expression Regulation, Neoplastic/drug effects, Humans, Inflammation/genetics, Inflammation/pathology, Kaplan-Meier Estimate, Lymphocytes, Tumor-Infiltrating/pathology, Middle Aged, Mutation, Precision Medicine, Prognosis, Programmed Cell Death 1 Receptor/genetics, Tumor Microenvironment/genetics, Adenocarcinoma, medicine.disease_cause, Article, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Immune system, Lymphocytes, Tumor-Infiltrating, Tumor Microenvironment, Medicine, Gastrointestinal cancer, Inflammation, business.industry, FOXP3, Anal canal, medicine.disease, Anus Neoplasms, Anal canal adenocarcinoma, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Anal gland, Cancer research, KRAS, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727b845e13b0a296918d858027e98dabTest
http://europepmc.org/articles/PMC5959925Test

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