المؤلفون: Rajewsky, Nikolaus, Almouzni, Geneviève, Gorski, Stanislaw, A, Aerts, Stein, Amit, Ido, Bertero, Michela, G, Bock, Christoph, Bredenoord, Annelien, L, Cavalli, Giacomo, Chiocca, Susanna, Clevers, Hans, de Strooper, Bart, Eggert, Angelika, Ellenberg, Jan, Fernández, Xosé, M, Figlerowicz, Marek, Gasser, Susan, M, Hubner, Norbert, Kjems, Jørgen, Knoblich, Jürgen, A, Krabbe, Grietje, Lichter, Peter, Linnarsson, Sten, Marine, Jean-Christophe, Marioni, John, C, Marti-Renom, Marc, A, Netea, Mihai, G, Nickel, Dörthe, Nollmann, Marcelo, Novak, Halina, R, Parkinson, Helen, Piccolo, Stefano, Pinheiro, Inês, Pombo, Ana, Popp, Christian, Reik, Wolf, Roman-Roman, Sergio, Rosenstiel, Philip, Schultze, Joachim, L, Stegle, Oliver, Tanay, Amos, Testa, Giuseppe, Thanos, Dimitris, Theis, Fabian, J, Torres-Padilla, Maria-Elena, Valencia, Alfonso, Vallot, Céline, van Oudenaarden, Alexander, Vidal, Marie, Voet, Thierry, Alberi, Lavinia, Alexander, Stephanie, Alexandrov, Theodore, Arenas, Ernest, Bagni, Claudia, Balderas, Robert, Bandelli, Andrea, Becher, Burkhard, Becker, Matthias, Beerenwinkel, Niko, Benkirame, Monsef, Beyer, Marc, Bickmore, Wendy, Biessen, Erik, E a L, Blomberg, Niklas, Blumcke, Ingmar, Bodenmiller, Bernd, Borroni, Barbara, Boumpas, Dimitrios, T, Bourgeron, Thomas, Bowers, Sarion, Braeken, Dries, Brooksbank, Catherine, Brose, Nils, Bruining, Hilgo, Bury, Jo, Caporale, Nicolo, Cattoretti, Giorgio, Chabane, Nadia, Chneiweiss, Hervé, Cook, Stuart, A, Curatolo, Paolo, de Jonge, Marien, I, Deplancke, Bart, de Witte, Peter, Dimmeler, Stefanie, Draganski, Bogdan, Drews, Anna, Dumbrava, Costica, Engelhardt, Stefan, Gasser, Thomas, Giamarellos-Bourboulis, Evangelos, J, Graff, Caroline, Grün, Dominic, Gut, Ivo, Hansson, Oskar, Henshall, David, C, Herland, Anna, Heutink, Peter, Heymans, Stephane, R B, Heyn, Holger, Huch, Meritxell, Huitinga, Inge, Jackowiak, Paulina, Jongsma, Karin, R, Journot, Laurent, Junker, Jan, Philipp, Katz, Shauna, Kehren, Jeanne, Kempa, Stefan, Kirchhof, Paulus, Klein, Christine, Koralewska, Natalia, Korbel, Jan, O, Kühnemund, Malte, Lamond, Angus, I, Lauwers, Elsa, Le Ber, Isabelle, Leinonen, Ville, Tobon, Alejandro, Lopez, Lundberg, Emma, Lunkes, Astrid, Maatz, Henrike, Mann, Matthias, Marelli, Luca, Matser, Vera, Matthews, Paul, M, Mechta-Grigoriou, Fatima, Menon, Radhika, Nielsen, Anne, F, Pagani, Massimiliano, Pasterkamp, R, Jeroen, Pitkänen, Asla, Popescu, Valentin, Pottier, Cyril, Puisieux, Alain, Rademakers, Rosa, Reiling, Dory, Reiner, Orly, Remondini, Daniel, Ritchie, Craig, Rohrer, Jonathan, D, Saliba, Antoine-Emmanuel, Sanchez-Valle, Raquel, Santosuosso, Amedeo, Sauter, Arnold, Scheltema, Richard, A, Scheltens, Philip, Schiller, Herbert, B, Schneider, Anja, Seibler, Philip, Sheehan-Rooney, Kelly, Shields, David, Sleegers, Kristel, Smit, August, B, Smith, Kenneth, G C, Smolders, Ilse, Synofzik, Matthis, Tam, Wai, Long, Teichmann, Sarah, Thom, Maria, Turco, Margherita, Y, van Beusekom, Heleen, M M, Vandenberghe, Rik, van den Hoecke, Silvie, van de Poel, Ibo, van der Ven, Andre, van der Zee, Julie, van Lunzen, Jan, van Minnebruggen, Geert, van Paesschen, Wim, van Swieten, John, van Vught, Remko, Verhage, Matthijs, Verstreken, Patrik, Villa, Carlo, Emanuele, Vogel, Jörg, von Kalle, Christof, Walter, Jörn, Weckhuysen, Sarah, Weichert, Wilko, Wood, Louisa, Ziegler, Anette-Gabriele, Zipp, Frauke, Benkirane, Monsef, Bickmore, Wendy A., Biessen, Erik E. A. L., Boumpas, Dimitrios T., Cook, Stuart A., Jonge, Marien I. De, Strooper, Bart De, Witte, Peter De, Giamarellos-Bourboulis, Evangelos J., Gut, Ivo G., Henshall, David C., Heymans, Stephane R. B., Jongsma, Karin R., Junker, Jan Philipp, Korbel, Jan O., Lamond, Angus I., Ber, Isabelle Le, López-Tobón, Alejandro, Matthews, Paul M., Nielsen, Anne F., Pasterkamp, R. Jeroen, Rohrer, Jonathan D., Scheltema, Richard A., Schiller, Herbert B., Shields, David J., Smit, August B., Smith, Kenneth G. C., Tam, Wai Long, Teichmann, Sarah A., Turco, Margherita Y., Beusekom, Heleen M. M. Van, Hoecke, Silvie van Den, Poel, Ibo van De, Ven, Andre van Der, Zee, Julie van Der, Lunzen, Jan Van, Minnebruggen, Geert Van, Oudenaarden, Alexander Van, Paesschen, Wim Van, Swieten, John C. Van, Vught, Remko Van, Villa, Carlo Emanuele, Kalle, Christof Von

المساهمون: Berlin Institute for Medical Systems Biology, Charité - UniversitätsMedizin = Charité - University Hospital Berlin, Berlin Institute of Health (BIH), German Center for Cardiovascular Research (DZHK), Dynamique du noyau Institut Curie, Institut Curie Paris -Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Catholic University of Leuven = Katholieke Universiteit Leuven (KU Leuven), Weizmann Institute of Science Rehovot, Israël, Barcelona Institute of Science and Technology (BIST), CeMM Research Center for Molecular Medicine Vienna, Austria, Austrian Academy of Sciences (OeAW), University Medical Center Utrecht (UMCU), Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), European Institute of Oncology Milan (ESMO), Royal Netherlands Academy of Arts and Sciences (KNAW), Oncode Institute Utrecht, Princess Máxima Center for Pediatric Oncology, University College of London London (UCL), European Molecular Biology Laboratory Heidelberg (EMBL), Institut Curie Paris, Polska Akademia Nauk = Polish Academy of Sciences = Académie polonaise des sciences (PAN), Poznan University of Technology (PUT), Friedrich Miescher Institute for Biomedical Research (FMI), Novartis Research Foundation, Université de Bâle = University of Basel = Basel Universität (Unibas), Max Delbrück Center for Molecular Medicine Berlin (MDC), Helmholtz-Gemeinschaft = Helmholtz Association, Aarhus University Aarhus, Medizinische Universität Wien = Medical University of Vienna, Centre de Biochimie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Génétique humaine et fonctions cognitives - Human Genetics and Cognitive Functions (GHFC (UMR_3571 / U-Pasteur_1)), Institut Pasteur Paris (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Neuroscience Paris Seine (NPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Plasticité gliale et neuro-oncologie = Glial Plasticity (NPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS)

المصدر: ISSN: 0028-0836.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32894860; hal-04023884; https://hal.sorbonne-universite.fr/hal-04023884Test; https://hal.sorbonne-universite.fr/hal-04023884v2/documentTest; https://hal.sorbonne-universite.fr/hal-04023884v2/file/s41586-020-2715-9.pdfTest; PUBMED: 32894860; PUBMEDCENTRAL: PMC7656507

الإتاحة: https://doi.org/10.1038/s41586-020-2715-9Test
https://hal.sorbonne-universite.fr/hal-04023884Test
https://hal.sorbonne-universite.fr/hal-04023884v2/documentTest
https://hal.sorbonne-universite.fr/hal-04023884v2/file/s41586-020-2715-9.pdfTest

المؤلفون: Clevers, Hans, de Strooper, Bart, Eggert, Angelika, Ellenberg, Jan, Fernández, Xosé, Figlerowicz, Marek, Gasser, Susan, Hubner, Norbert, Kjems, Jørgen, Knoblich, Jürgen, Krabbe, Grietje, Lichter, Peter, Linnarsson, Sten, Marine, Jean-Christophe, Marioni, John, Marti-Renom, Marc, Netea, Mihai, Nickel, Dörthe, Nollmann, Marcelo, Novak, Halina, Parkinson, Helen, Piccolo, Stefano, Pinheiro, Inês, Pombo, Ana, Popp, Christian, Reik, Wolf, Roman-Roman, Sergio, Rosenstiel, Philip, Schultze, Joachim, Stegle, Oliver, Tanay, Amos, Testa, Giuseppe, Thanos, Dimitris, Theis, Fabian, Torres-Padilla, Maria-Elena, Valencia, Alfonso, Vallot, Céline, van Oudenaarden, Alexander, Vidal, Marie, Voet, Thierry, Rajewsky, Nikolaus, Almouzni, Geneviève, Gorski, Stanislaw, A, Aerts, Stein, Amit, Ido, Bertero, Michela, G, Bock, Christoph, Bredenoord, Annelien, L, Cavalli, Giacomo, Chiocca, Susanna

المساهمون: Institut Curie Paris, Dynamique du noyau Institut Curie, Institut Curie Paris -Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0028-0836.

مصطلحات موضوعية: Systems biology, Biomarkers, Diseases, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32894860; hal-03027059; https://hal.science/hal-03027059Test; https://hal.science/hal-03027059/documentTest; https://hal.science/hal-03027059/file/LifeTime_white_paper_v22.pdfTest; PUBMED: 32894860

الإتاحة: https://doi.org/10.1038/s41586-020-2715-9Test
https://hal.science/hal-03027059Test
https://hal.science/hal-03027059/documentTest
https://hal.science/hal-03027059/file/LifeTime_white_paper_v22.pdfTest

المؤلفون: Semrau, Stefan, Goldmann, Johanna E., Soumillon, Magali, Mikkelsen, Tarjei S., Jaenisch, Rudolf, van Oudenaarden, Alexander

المساهمون: Massachusetts Institute of Technology. Department of Biology, Jaenisch, Rudolf

المصدر: Nature

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/S41467-017-01076-4Test; Nature Communications; http://hdl.handle.net/1721.1/114774Test; Semrau, Stefan et al. “Dynamics of Lineage Commitment Revealed by Single-Cell Transcriptomics of Differentiating Embryonic Stem Cells.” Nature Communications 8, 1 (October 2017): 1096 © 2017 The Author(s)

الإتاحة: https://doi.org/10.1038/S41467-017-01076-4Test
http://hdl.handle.net/1721.1/114774Test

المؤلفون: Kienle, Simone, Huelsz-Prince, Guizela, Barkoulas, Michalis, van Oudenaarden, Alexander, Van Zon, Jeroen Sebastiaan

المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Koch Institute for Integrative Cancer Research at MIT, van Zon, Jeroen Sebastiaan, van Oudenaarden, Alexander

المصدر: Nature Publishing Group

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/ncomms8053Test; Nature Communications; http://hdl.handle.net/1721.1/97210Test; Van Zon, Jeroen Sebastiaan, Simone Kienle, Guizela Huelsz-Prince, Michalis Barkoulas, and Alexander van Oudenaarden. “Cells Change Their Sensitivity to an EGF Morphogen Gradient to Control EGF-Induced Gene Expression.” Nature Communications 6 (May 11, 2015): 7053. © 2015 Macmillan Publishers Limited

الإتاحة: https://doi.org/10.1038/ncomms8053Test
http://hdl.handle.net/1721.1/97210Test

المؤلفون: van Oudenaarden, Alexander, Kung, Kevin S., Lyubimova, Anna, Agus, David B., Choi, Nathan C., Hillis, Daniel, Joo, Ahyoung, Katz, Jonathan E., Mallick, Parag, Mumenthaler, Shannon M., Wan, Jenny C., Alexander, Jenolyn F., Decuzzi, Paolo, Ferrari, Mauro, Godin, Biana, Srinivasan, Srimeenakshi, Arap, Wadih, Pasqualini, Renata, Ashili, Shashanka, Jacks, Tyler E

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Koch Institute for Integrative Cancer Research at MIT, Jacks, Tyler E., van Oudenaarden, Alexander, Kung, Kevin S., Lyubimova, Anna

المصدر: Scientific Reports

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/srep01449Test; Scientific Reports; http://hdl.handle.net/1721.1/84645Test; Agus, David B., Jenolyn F. Alexander, Wadih Arap, Shashanka Ashili, Joseph E. Aslan, Robert H. Austin, Vadim Backman, et al. “A physical sciences network characterization of non-tumorigenic and metastatic cells.” Scientific Reports 3 (April 26, 2013).; orcid:0000-0001-5785-8911; orcid:0000-0001-7080-9196

الإتاحة: https://doi.org/10.1038/srep01449Test
http://hdl.handle.net/1721.1/84645Test

المؤلفون: Tan, Rui Zhen, Ji, Ni, Mentink, Remco A., Korswagen, Hendrik C., van Oudenaarden, Alexander

المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology. Department of Physics, Ji, Ni, van Oudenaarden, Alexander

المصدر: Nature

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/msb.2012.64Test; Molecular Systems Biology; http://hdl.handle.net/1721.1/76627Test; Tan, Rui Zhen et al. “Deconvolving the Roles of Wnt Ligands and Receptors in Sensing and Amplification.” Molecular Systems Biology 9 (2013).

الإتاحة: https://doi.org/10.1038/msb.2012.64Test
http://hdl.handle.net/1721.1/76627Test

المؤلفون: Hebenstreit, Daniel, Fang, Miaoqing, Charoensawan, Varodom, van Oudenaarden, Alexander, Teichmann, Sarah A.

المساهمون: Massachusetts Institute of Technology. Department of Biological Engineering, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, van Oudenaarden, Alexander, Fang, Miaoqing

المصدر: Prof. van Oudenaarden via Mat Willmott

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/msb.2011.28Test; Molecular Systems Biology; http://hdl.handle.net/1721.1/71571Test; Hebenstreit, Daniel et al. “RNA sequencing reveals two major classes of gene expression levels in metazoan cells.” Molecular Systems Biology 7 (2011)

الإتاحة: https://doi.org/10.1038/msb.2011.28Test
http://hdl.handle.net/1721.1/71571Test

المؤلفون: Itzkovitz, Shaul Shalev, van Oudenaarden, Alexander

المساهمون: MIT Materials Research Laboratory, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Koch Institute for Integrative Cancer Research at MIT, van Oudenaarden, Alexander, Itzkovitz, Shaul Shalev

المصدر: Prof. van Oudenaarden via Mat Wilmott

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/nmeth.1573Test; Nature Methods; http://hdl.handle.net/1721.1/71013Test; Itzkovitz, Shalev, and Alexander van Oudenaarden. “Validating transcripts with probes and imaging technology.” Nature Methods 8.4s (2011): S12-S19.

الإتاحة: https://doi.org/10.1038/nmeth.1573Test
http://hdl.handle.net/1721.1/71013Test

المؤلفون: van Oudenaarden, Alexander, Rifkin, Scott A., Raj, Arjun, Andersen, Erik C.

المساهمون: Massachusetts Institute of Technology. Department of Physics, van Oudenaarden, Alexander, Rifkin, Scott A., Raj, Arjun, Andersen, Erik C.

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/nature08781Test; Nature; http://hdl.handle.net/1721.1/76649Test; Raj, Arjun et al. “Variability in Gene Expression Underlies Incomplete Penetrance.” Nature 463.7283 (2010): 913–918.

الإتاحة: https://doi.org/10.1038/nature08781Test
http://hdl.handle.net/1721.1/76649Test

المؤلفون: Mukherji, Shankar, Ebert, Margaret S., Sharp, Phillip A., van Oudenaarden, Alexander, Tsang, John S., Zheng, Xinying Grace

المساهمون: Harvard University--MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology. Computational and Systems Biology Program, Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Physics, Koch Institute for Integrative Cancer Research at MIT, Mukherji, Shankar, Ebert, Margaret S., Zheng, Grace X. Y., Sharp, Phillip A., van Oudenaarden, Alexander

المصدر: PMC

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1038/ng.905Test; Nature Genetics; http://hdl.handle.net/1721.1/74623Test; Mukherji, Shankar et al. “MicroRNAs Can Generate Thresholds in Target Gene Expression.” Nature Genetics 43.9 (2011): 854–859.; orcid:0000-0003-1465-1691

الإتاحة: https://doi.org/10.1038/ng.905Test
http://hdl.handle.net/1721.1/74623Test