المؤلفون: Andrio, Emilie, Lotte, Romain, Hamaoui, Daniel, Cherfils, Jacqueline, Doye, Anne, Daugaard, Mads, Sørensen, Poul, Bost, Frédéric, Ruimy, Raymond, Mettouchi, Amel, Lemichez, Emmanuel

المساهمون: Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Toxines bactériennes dans la relation hôtes-pathogènes, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Laboratoire de Bactériologie CHU Nice, Centre Hospitalier Universitaire de Nice (CHU Nice)-Hôpital Archet 2 Nice (CHU), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), University of British Columbia (UBC), Vancouver Prostate Centre Vancouver General Hospital (VPC), Vancouver General Hospital, BC Cancer Agency Research Centre (BCCRC), Signalisation moléculaire et obésité, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by INSERM, CNRS and fundings from the Ligue Nationale Contre le Cancer (LNCC, équipe labellisée), Association pour la Recherche sur le Cancer (ARC-SFI20111203659 & ARC-SFI20111203671), a fellowship LNCC to D.H., a PhD fellowship from the “Fondation pour la Recherche Médicale” (FRM-FDM20150632804) to R.L., We are grateful to Melissa Sivaneson, Frédéric Reinier and Patrick Munro for technical help and fruitful discussions. We thank Orane Visvikis for critical reading of the manuscript.

المصدر: ISSN: 2045-2322.

مصطلحات موضوعية: Proteolysis, Cell biology, MESH: Amino Acid Sequence, MESH: Cell Line, MESH: Models, Molecular, MESH: Mutant Proteins/chemistry, MESH: Mutation, Missense/genetics, MESH: Neoplasms/genetics, MESH: Protein Binding, MESH: Protein Domains, MESH: Structure-Activity Relationship, MESH: Ubiquitin-Protein Ligases/chemistry, MESH: Ubiquitin-Protein Ligases/genetics, MESH: Ubiquitin-Protein Ligases/metabolism, MESH: Ubiquitination, MESH: rac1 GTP-Binding Protein/metabolism, MESH: Cell Proliferation, MESH: Humans, [SDV]Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28317937; pasteur-02448600; https://pasteur.hal.science/pasteur-02448600Test; https://pasteur.hal.science/pasteur-02448600/documentTest; https://pasteur.hal.science/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest; PUBMED: 28317937; PUBMEDCENTRAL: PMC5357957

الإتاحة: https://doi.org/10.1038/srep44779Test
https://pasteur.hal.science/pasteur-02448600Test
https://pasteur.hal.science/pasteur-02448600/documentTest
https://pasteur.hal.science/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest

المؤلفون: Andrio, Emilie, Lotte, Romain, Hamaoui, Daniel, Cherfils, Jacqueline, Doye, Anne, Daugaard, Mads, Sørensen, Poul, Bost, Frédéric, Ruimy, Raymond, Mettouchi, Amel, Lemichez, Emmanuel

المساهمون: Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Toxines bactériennes dans la relation hôtes-pathogènes, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Laboratoire de Bactériologie CHU Nice, Centre Hospitalier Universitaire de Nice (CHU Nice)-Hôpital Archet 2 Nice (CHU), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), University of British Columbia (UBC), Vancouver Prostate Centre Vancouver General Hospital (VPC), Vancouver General Hospital, BC Cancer Agency Research Centre (BCCRC), Signalisation moléculaire et obésité, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by INSERM, CNRS and fundings from the Ligue Nationale Contre le Cancer (LNCC, équipe labellisée), Association pour la Recherche sur le Cancer (ARC-SFI20111203659 & ARC-SFI20111203671), a fellowship LNCC to D.H., a PhD fellowship from the “Fondation pour la Recherche Médicale” (FRM-FDM20150632804) to R.L., We are grateful to Melissa Sivaneson, Frédéric Reinier and Patrick Munro for technical help and fruitful discussions. We thank Orane Visvikis for critical reading of the manuscript.

المصدر: ISSN: 2045-2322.

مصطلحات موضوعية: Proteolysis, Cell biology, MESH: Amino Acid Sequence, MESH: Cell Line, MESH: Models, Molecular, MESH: Mutant Proteins/chemistry, MESH: Mutation, Missense/genetics, MESH: Neoplasms/genetics, MESH: Protein Binding, MESH: Protein Domains, MESH: Structure-Activity Relationship, MESH: Ubiquitin-Protein Ligases/chemistry, MESH: Ubiquitin-Protein Ligases/genetics, MESH: Ubiquitin-Protein Ligases/metabolism, MESH: Ubiquitination, MESH: rac1 GTP-Binding Protein/metabolism, MESH: Cell Proliferation, MESH: Humans, [SDV]Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28317937; pasteur-02448600; https://pasteur.hal.science/pasteur-02448600Test; https://pasteur.hal.science/pasteur-02448600/documentTest; https://pasteur.hal.science/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest; PUBMED: 28317937; PUBMEDCENTRAL: PMC5357957

الإتاحة: https://doi.org/10.1038/srep44779Test
https://pasteur.hal.science/pasteur-02448600Test
https://pasteur.hal.science/pasteur-02448600/documentTest
https://pasteur.hal.science/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest

المؤلفون: Andrio, Emilie, Lotte, Romain, Hamaoui, Daniel, Cherfils, Jacqueline, Doye, Anne, Daugaard, Mads, Sørensen, Poul, Bost, Frédéric, Ruimy, Raymond, Mettouchi, Amel, Lemichez, Emmanuel

المساهمون: Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Toxines bactériennes dans la relation hôtes-pathogènes, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UniCA), Laboratoire de Bactériologie CHU Nice, Centre Hospitalier Universitaire de Nice (CHU Nice)-Hôpital Archet 2 Nice (CHU), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), University of British Columbia (UBC), Vancouver Prostate Centre Vancouver General Hospital (VPC), Vancouver General Hospital, BC Cancer Agency Research Centre (BCCRC), Signalisation moléculaire et obésité, Université Nice Sophia Antipolis (1965 - 2019) (UNS)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by INSERM, CNRS and fundings from the Ligue Nationale Contre le Cancer (LNCC, équipe labellisée), Association pour la Recherche sur le Cancer (ARC-SFI20111203659 & ARC-SFI20111203671), a fellowship LNCC to D.H., a PhD fellowship from the “Fondation pour la Recherche Médicale” (FRM-FDM20150632804) to R.L., We are grateful to Melissa Sivaneson, Frédéric Reinier and Patrick Munro for technical help and fruitful discussions. We thank Orane Visvikis for critical reading of the manuscript.

المصدر: ISSN: 2045-2322.

مصطلحات موضوعية: Proteolysis, Cell biology, MESH: Amino Acid Sequence, MESH: Cell Line, MESH: Models, Molecular, MESH: Mutant Proteins/chemistry, MESH: Mutation, Missense/genetics, MESH: Neoplasms/genetics, MESH: Protein Binding, MESH: Protein Domains, MESH: Structure-Activity Relationship, MESH: Ubiquitin-Protein Ligases/chemistry, MESH: Ubiquitin-Protein Ligases/genetics, MESH: Ubiquitin-Protein Ligases/metabolism, MESH: Ubiquitination, MESH: rac1 GTP-Binding Protein/metabolism, MESH: Cell Proliferation, MESH: Humans, [SDV]Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28317937; pasteur-02448600; https://pasteur.hal.science/pasteur-02448600Test; https://pasteur.hal.science/pasteur-02448600/documentTest; https://pasteur.hal.science/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest; PUBMED: 28317937; PUBMEDCENTRAL: PMC5357957

الإتاحة: https://doi.org/10.1038/srep44779Test
https://pasteur.hal.science/pasteur-02448600Test
https://pasteur.hal.science/pasteur-02448600/documentTest
https://pasteur.hal.science/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest

المؤلفون: Andrio, Emilie, Lotte, Romain, Hamaoui, Daniel, Cherfils, Jacqueline, Doye, Anne, Daugaard, Mads, Sørensen, Poul, Bost, Frédéric, Ruimy, Raymond, Mettouchi, Amel, Lemichez, Emmanuel

المساهمون: Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (. - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Toxines bactériennes dans la relation hôtes-pathogènes, Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR50-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (. - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Laboratoire de Bactériologie CHU Nice, Centre Hospitalier Universitaire de Nice (CHU Nice)-Hôpital Archet 2 Nice (CHU), Laboratoire de Biologie et de Pharmacologie Appliquée (LBPA), École normale supérieure - Cachan (ENS Cachan)-Centre National de la Recherche Scientifique (CNRS), University of British Columbia (UBC), Vancouver Prostate Centre Vancouver General Hospital (VPC), Vancouver General Hospital, BC Cancer Agency Research Centre (BCCRC), Signalisation moléculaire et obésité, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by INSERM, CNRS and fundings from the Ligue Nationale Contre le Cancer (LNCC, équipe labellisée), Association pour la Recherche sur le Cancer (ARC-SFI20111203659 & ARC-SFI20111203671), a fellowship LNCC to D.H., a PhD fellowship from the “Fondation pour la Recherche Médicale” (FRM-FDM20150632804) to R.L., We are grateful to Melissa Sivaneson, Frédéric Reinier and Patrick Munro for technical help and fruitful discussions. We thank Orane Visvikis for critical reading of the manuscript.

المصدر: ISSN: 2045-2322.

مصطلحات موضوعية: Cell biology, Proteolysis, MESH: Amino Acid Sequence, MESH: Cell Line, MESH: Models, Molecular, MESH: Mutant Proteins/chemistry, MESH: Mutation, Missense/genetics, MESH: Neoplasms/genetics, MESH: Protein Binding, MESH: Protein Domains, MESH: Structure-Activity Relationship, MESH: Ubiquitin-Protein Ligases/chemistry, MESH: Ubiquitin-Protein Ligases/genetics, MESH: Ubiquitin-Protein Ligases/metabolism, MESH: Ubiquitination, MESH: rac1 GTP-Binding Protein/metabolism, MESH: Cell Proliferation, MESH: Humans, [SDV]Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28317937; pasteur-02448600; https://hal-pasteur.archives-ouvertes.fr/pasteur-02448600Test; https://hal-pasteur.archives-ouvertes.fr/pasteur-02448600/documentTest; https://hal-pasteur.archives-ouvertes.fr/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest; PUBMED: 28317937; PUBMEDCENTRAL: PMC5357957

الإتاحة: https://doi.org/10.1038/srep44779Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-02448600Test
https://hal-pasteur.archives-ouvertes.fr/pasteur-02448600/documentTest
https://hal-pasteur.archives-ouvertes.fr/pasteur-02448600/file/Identification_of_cancer_associated_missense_mutations.pdfTest