التفاصيل البيبلوغرافية
| العنوان: |
A genome-wide association study of marginal zone lymphoma shows association to the HLA region |
| المؤلفون: |
Vijai, Joseph, Wang, Zhaoming, Berndt, Sonja I., Skibola, Christine F., Slager, Susan L., Sanjosé Llongueras, Silvia de, Melbye, Mads, Glimelius, Bengt, Bracci, Paige M., Conde, Lucía, Birmann, Brenda M., Diver, W. Ryan, Vajdic, Claire M., Armstrong, Bruce K., Kricker, Anne, Zheng, Tongzhang, Holford, Theodore R., Severi, Gianluca, Vineis, Paolo, Ferri, Giovanni M., Ricco, Rosalia, Miligi, Lucia, Clavel, Jacqueline, Giovannucci, Edward L., Kraft, Peter, Virtamo, Jarmo, Smith, Alex, Kane, Eleanor, Roman, Eve, Chiu, Brian C. H., Fraumeni, Joseph F., Wu, Xifeng, Cerhan, James R., Offit, Kenneth, Chanock, Stephen J., Rothman, Nathaniel, Nieters, Alexandra, Wang, Sophia S., Brooks-Wilson, Angela R., Lan, Qing, Bakker, Paul I. W. de, Vermeulen, Roel C. H., Portlock, Carol, Ansell, Stephen M., Link, Brian K., Riby, Jacques, North, Kari E., Gu, Jian, Hjalgrim, Henrik, Cozen, Wendy, Becker, Nikolaus, Teras, Lauren R., Spinelli, John J., Turner, Jenny, Zhang, Yawei, Purdue, Mark P., Giles, Graham G., Kelly, Rachel S., Zeleniuch-Jacquotte, Anne, Ennas, Maria Grazia, Monnereau, Alain, Bertrand, Kimberly A., Albanes, Demetrius, Lightfoot, Tracy, Yeager, Meredith, Chung, Charles C., Burdett, Laurie, Hutchinson, Amy, Lawrence, Charles, Montalvan, Rebecca, Liang, Liming, Huang, Jinyan, Ma, Baoshan, Villano, Danylo J., Maria, Ann, Corines, Marina, Thomas, Tinu, Novak, Anne J., Dogan, Ahmet, Liebow, Mark, Thompson, Carrie A., Witzig, Thomas E., Habermann, Thomas M., Weiner, George J., Smith, Martyn T., Holly, Elizabeth A., Jackson, Rebecca D. J., Tinker, Lesley F., Ye, Yuanqing, Adami, Hans-Olov, Smedby, Karin E., Roos, Anneclaire J. De, Hartge, Patricia, Morton, Lindsay M., Severson, Richard K., Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Foretova, Lenka, Maynadié, Marc, McKay, James D., Staines, Anthony |
| المصدر: |
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
| بيانات النشر: |
Nature Publishing Group |
| سنة النشر: |
2015 |
| المجموعة: |
Dipòsit Digital de la Universitat de Barcelona |
| مصطلحات موضوعية: |
Malaltia de Hodgkin, Cèl·lules B, Hodgkin's disease, B cells |
| الوصف: |
Marginal zone lymphoma (MZL) is the third most common subtype of B-cell non-Hodgkin lymphoma. Here we perform a two-stage GWAS of 1,281 MZL cases and 7,127 controls of European ancestry and identify two independent loci near BTNL2 (rs9461741, P - 3.95 x 10(-15)) and HLA-B (rs2922994, P - 2.43 x 10(-9)) in the HLA region significantly associated with MZL risk. This is the first evidence that genetic variation in the major histocompatibility complex influences MZL susceptibility. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Reproducció del document publicat a: https://doi.org/10.1038/ncomms6751Test; Nature Communications, 2015, vol. 6; https://doi.org/10.1038/ncomms6751Test; http://hdl.handle.net/2445/126171Test |
| الإتاحة: |
https://doi.org/10.1038/ncomms6751Test
http://hdl.handle.net/2445/126171Test |
| حقوق: |
cc by (c) Vijai et al., 2015 ; http://creativecommons.org/licenses/by/3.0/esTest/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.987C141D |
| قاعدة البيانات: |
BASE |
