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المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Gomes, C, Gayden, T, Bajic, A, Harraz, O, Pratt, J, Nikbakht, H, Bareke, E, Goncalves, M, Castro, W, St-Onge, P, Sinnett, D, Han, H, Rivera, B, Mikael, L, DeJay, N, Kleinman, C, Valera, E, Bassenden, A, Berghuis, A, Majewski, J, Nelson, M, Gomez, R & Jabado, N 2018, ' TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw ', Nature Communications, vol. 9, no. 1, pp. 4572 . https://doi.org/10.1038/s41467-018-06690-4Test
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Patch-Clamp Techniques, Somatic cell, General Physics and Astronomy, medicine.disease_cause, Jaw Neoplasms/genetics, Whole Exome Sequencing, Receptor, Child, lcsh:Science, Exome sequencing, Giant Cell Tumor of Bone, Multidisciplinary, High-Throughput Nucleotide Sequencing, Middle Aged, Jaw Neoplasms, 3. Good health, Gain of Function Mutation, Female, KRAS, TRPV4, Adult, Giant Cell Tumor of Bone/genetics, Adolescent, MAP Kinase Signaling System, Science, TRPV Cation Channels, TRPV Cation Channels/genetics, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Proto-Oncogene Proteins p21(ras), Proto-Oncogene Proteins p21(ras)/genetics, 03 medical and health sciences, Young Adult, Exome Sequencing, medicine, Humans, Computer Simulation, Receptor, Fibroblast Growth Factor, Type 1, Aged, Receptor, Fibroblast Growth Factor, Type 1/genetics, Sequence Analysis, RNA, HEK 293 cells, General Chemistry, Sequence Analysis, DNA, stomatognathic diseases, 030104 developmental biology, HEK293 Cells, Giant cell, Cancer research, lcsh:Q

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be0322012f1773bb260e639e107111bTest
http://link.springer.com/article/10.1038/s41467-018-06690-4Test

39

Untargeted Metabolite Profiling of Cerebrospinal Fluid Uncovers Biomarkers for Severity of Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2, Batten Disease)

المؤلفون: Jonathan P. Dyke, Barry E. Kosofsky, Dolan Sondhi, Douglas Ballon, Stephen M. Kaminsky, Miriam Sindelar, Ronald G. Crystal, Steven S. Gross, Ruba S. Deeb

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Male, Metabolite, lcsh:Medicine, Disease, Acetates, Aminopeptidases, Severity of Illness Index, chemistry.chemical_compound, Cerebrospinal fluid, Child, lcsh:Science, Neurons, Multidisciplinary, Tripeptidyl-Peptidase 1, Neurodegeneration, Brain, Middle Aged, 3. Good health, Mitochondria, Child, Preschool, Metabolome, Female, Adult, Batten disease, Adolescent, Article, Lipofuscin, 03 medical and health sciences, Young Adult, Metabolomics, Neuronal Ceroid-Lipofuscinoses, Severity of illness, medicine, Animals, Humans, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Aged, business.industry, lcsh:R, medicine.disease, Disease Models, Animal, 030104 developmental biology, chemistry, Immunology, lcsh:Q, Serine Proteases, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa2f254033554dfd856fcfa9bfb12fcTest
http://link.springer.com/article/10.1038/s41598-018-33449-0Test

40

Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway

المؤلفون: Zhong-Fa Lu, Lijuan Zhou, Jing Jing, Lijuan Yu, Han Wang, Xian-Jie Wu

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Adolescent, Lymphoid Enhancer-Binding Factor 1, Cell, lcsh:Medicine, Outer root sheath, Article, 03 medical and health sciences, Mice, Young Adult, Cornus, Downregulation and upregulation, Proto-Oncogene Proteins, medicine, Loose Anagen Hair Syndrome, Animals, Humans, Glycosides, lcsh:Science, Wnt Signaling Pathway, Cells, Cultured, beta Catenin, Cell Proliferation, Multidisciplinary, integumentary system, Chemistry, lcsh:R, Wnt signaling pathway, Alopecia, Middle Aged, medicine.disease, In vitro, Cell biology, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, medicine.anatomical_structure, Hair loss, DKK1, Intercellular Signaling Peptides and Proteins, Female, lcsh:Q, Signal transduction, Hair Follicle, Hair

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc56d7aadcf4f24e2d2ceda364521b79Test
http://link.springer.com/article/10.1038/s41598-018-32138-2Test

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