نتائج البحث

1

Combination of anti-PD-1 antibody with P-GEMOX as a potentially effective immunochemotherapy for advanced natural killer/T cell lymphoma

المؤلفون: Yan Gao, Jun Cai, Yi Xia, Qingqing Cai, Shuyun Ma, Yuchen Zhang, Lirong Li, Xiaopeng Tian, Hang Yang, Panpan Liu, Yajun Li, Xuanye Zhang, Hui Zhou, Huiqiang Huang

المصدر: Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-9 (2020)
Signal Transduction and Targeted Therapy

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Antibodies, Neoplasm, Programmed Cell Death 1 Receptor, lcsh:Medicine, Gastroenterology, Deoxycytidine, Polyethylene Glycols, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, T-cell lymphoma, lcsh:QH301-705.5, Middle Aged, Neoplasm Proteins, Lymphoma, Extranodal NK-T-Cell, Oxaliplatin, Survival Rate, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, medicine.medical_specialty, Drug development, GemOx, Neutropenia, Predictive markers, Article, Disease-Free Survival, 03 medical and health sciences, Fluorodeoxyglucose F18, Internal medicine, Genetics, medicine, Asparaginase, Humans, Survival rate, Aged, Pegaspargase, Haematological cancer, business.industry, lcsh:R, medicine.disease, Gemcitabine, Regimen, 030104 developmental biology, lcsh:Biology (General), Positron-Emission Tomography, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aa20c22427d24bef448ec18145aa9bTest
https://doaj.orgTest/article/99ff2da0b38046018a5c7ce878c81a7f

2

Baseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients

المؤلفون: Davide Ciardiello, Teresa Troiani, Erika Martinelli, N. Zanaletti, Stefania Napolitano, P. Vitale, Giusi Barra, Raffaele De Palma, Vincenzo De Falco, M. Terminiello, Floriana Morgillo, Emilio Francesco Giunta, Giuseppe Argenziano, Fortunato Ciardiello

المساهمون: Giunta, Emilio Francesco, Barra, Giusi, De Falco, Vincenzo, Argenziano, Giuseppe, Napolitano, Stefania, Vitale, Pasquale, Zanaletti, Nicoletta, Terminiello, Marinella, Martinelli, Erika, Morgillo, Floriana, Ciardiello, Davide, De Palma, Raffaele, Ciardiello, Fortunato, Troiani, Teresa

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c64fa57985a2b5d76692b374d5b40dfTest
http://link.springer.comTest/article/10.1038/s41598-020-72711-2

3

Effect of drug metabolizing enzymes and transporters in Thai colorectal cancer patients treated with irinotecan-based chemotherapy

المؤلفون: Apichaya Puangpetch, Phichai Chansriwong, Ekaphop Sirachainan, Suwannee Sirilerttrakul, Chonlaphat Sukasem, Monpat Chamnanphon, Thanyanan Reungwetwattana, Chalirmporn Atasilp

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Genetic testing, Colorectal cancer, lcsh:Medicine, 0302 clinical medicine, Gene Frequency, Genetics research, Cytochrome P-450 CYP3A, Glucuronosyltransferase, lcsh:Science, Multidisciplinary, Molecular medicine, Middle Aged, Thailand, Multidrug Resistance-Associated Protein 2, Population study, Female, Multidrug Resistance-Associated Proteins, Colorectal Neoplasms, medicine.drug, Adult, medicine.medical_specialty, Neutropenia, Genotype, Irinotecan, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, CYP3A5, Allele frequency, Alleles, Aged, Polymorphism, Genetic, business.industry, lcsh:R, Genetic Variation, Membrane Transport Proteins, medicine.disease, Personalized medicine, Genotype frequency, 030104 developmental biology, Genetic markers, DPYD, ATP-Binding Cassette Transporters, lcsh:Q, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd7951ea617b032dfd1c624b20a74d5Test
http://link.springer.comTest/article/10.1038/s41598-020-70351-0

4

The Prognostic Value of Deficient Mismatch Repair in Stage II–IVa Nasopharyngeal Carcinoma in the Era of IMRT

المؤلفون: Jian-fang Gao, Hong-xing Kan, Yun-Xiang Zhang, Ming-chen Wang, Ya-nan Zhang, Shi-geng Zhang, Ya-ting Zhang, Fu-Rong Hao, Fang-ming Chen, Han Li, Cheng Li, Yang Li, Xiu-feng Li, Hao Ma, Xiao-li Wang

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Biopsy, medicine.medical_treatment, lcsh:Medicine, DNA Mismatch Repair, 0302 clinical medicine, PMS2, Stage (cooking), Child, lcsh:Science, Cancer, Mismatch Repair Endonuclease PMS2, Aged, 80 and over, Nasopharyngeal Carcinoma, Multidisciplinary, Middle Aged, Prognosis, DNA-Binding Proteins, MutS Homolog 2 Protein, 030220 oncology & carcinogenesis, Female, MutL Protein Homolog 1, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Article, Disease-Free Survival, Young Adult, 03 medical and health sciences, Medical research, Internal medicine, medicine, Humans, Aged, Neoplasm Staging, Proportional hazards model, business.industry, lcsh:R, Nasopharyngeal Neoplasms, medicine.disease, digestive system diseases, Radiation therapy, MSH6, 030104 developmental biology, Nasopharyngeal carcinoma, MSH2, lcsh:Q, Radiotherapy, Intensity-Modulated, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d767a9c5809441e5e350293f161468b0Test
http://link.springer.comTest/article/10.1038/s41598-020-66678-3

5

The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia

المؤلفون: Yabo Ouyang, Dexi Chen, Lijun Pang, Xianghua Guo, Ronghua Jin, Jiming Yin, Ying-Mei Feng, Hongbo Shi, Honglin Shi, Wenjing Wang, Luxin Qiao

المصدر: Cell Death and Disease, Vol 11, Iss 6, Pp 1-8 (2020)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lymphocyte, CD8-Positive T-Lymphocytes, 0302 clinical medicine, STAT5 Transcription Factor, Cytotoxic T cell, IL-2 receptor, Aged, 80 and over, lcsh:Cytology, Middle Aged, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Coronavirus Infections, medicine.drug, Interleukin 2, Adult, medicine.medical_specialty, T cell, Critical Illness, Immunology, Pneumonia, Viral, Peripheral blood mononuclear cell, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Betacoronavirus, Immune system, Internal medicine, medicine, Humans, Lymphocyte Count, lcsh:QH573-671, Pandemics, Aged, business.industry, SARS-CoV-2, Interleukins, Tumor Suppressor Proteins, Interleukin-2 Receptor alpha Subunit, COVID-19, Cell Biology, Janus Kinase 1, medicine.disease, Pneumonia, 030104 developmental biology, Viral infection, Interleukin-2, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54f768432e3b5857a30940e825993ceTest
http://link.springer.comTest/article/10.1038/s41419-020-2636-4

6

Multiplexed MRM-based protein quantification of putative prognostic biomarkers for chronic kidney disease progression in plasma

المؤلفون: Àngel Argilés, Vasiliki Lygirou, Eleni Petra, Flore Duranton, Harald Mischak, Manousos Makridakis, Jerome Zoidakis, Szymon Filip, Antonia Vlahou, Georgia Kontostathi, Rafael Stroggilos

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, 030232 urology & nephrology, lcsh:Medicine, Disease, Mass Spectrometry, Cohort Studies, Prognostic markers, 0302 clinical medicine, Multiplex, Longitudinal Studies, lcsh:Science, Aged, 80 and over, Multidisciplinary, Immunoglobulin heavy constant alpha 1, Middle Aged, Prognosis, Blood proteins, Hemoglobin Subunits, Disease Progression, Female, medicine.symptom, Complement C1 Inhibitor Protein, Glomerular Filtration Rate, Adult, medicine.medical_specialty, Quantitative proteomics, Proteomic analysis, Renal function, Article, 03 medical and health sciences, Internal medicine, Alpha-Globulins, medicine, Humans, Renal Insufficiency, Chronic, Aged, business.industry, lcsh:R, medicine.disease, 030104 developmental biology, Albuminuria, Muramidase, lcsh:Q, beta 2-Microglobulin, business, Biomarkers, Follow-Up Studies, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45ed4d3b1c70609a58b348a2d897aa9Test
http://link.springer.comTest/article/10.1038/s41598-020-61496-z

7

Immunoprofiling of Colitis-associated and Sporadic Colorectal Cancer and its Clinical Significance

المؤلفون: Jeong-Sik Byeon, Sang-Yeob Kim, Su In Jo, Jae Seung Soh, Sung Wook Hwang, Dong-Hoon Yang, Suk-Kyun Yang, Jihun Kim, Sang Hyoung Park, Eun-Ju Do, Hye Jin Lee, Seung-Jae Myung, Byong Duk Ye

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer microenvironment, Adult, Male, medicine.medical_specialty, CD3 Complex, medicine.medical_treatment, Programmed Cell Death 1 Receptor, lcsh:Medicine, CD8-Positive T-Lymphocytes, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal medicine, Neoplasms, Medicine, Humans, Clinical significance, cardiovascular diseases, Colitis, lcsh:Science, Aged, Multidisciplinary, business.industry, lcsh:R, FOXP3, Cancer, nutritional and metabolic diseases, Forkhead Transcription Factors, Immunotherapy, Middle Aged, medicine.disease, Immunohistochemistry, Colon cancer, 030104 developmental biology, Female, lcsh:Q, business, Colorectal Neoplasms, 030217 neurology & neurosurgery, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57b8b93981a47c773eff93736694474Test
http://link.springer.comTest/article/10.1038/s41598-019-42986-1

8

Mitochondrial haplogroups are not associated with diabetic retinopathy in a large Australian and British Caucasian sample

المؤلفون: Bishwanath Pal, Ebony Liu, Rohan W Essex, Sotoodeh Abhary, Georgia Kaidonis, Jamie E Craig, Mark C Gillies, Alicia J. Jenkins, Ecosse L. Lamoureux, Jonathan M. Gleadle, John H Chang, Jolly Gilhotra, Kathryn P. Burdon, Nikolai Petrovsky, Mark Daniell, Alex W. Hewitt, Stewart Lake

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system diseases, genetic structures, lcsh:Medicine, Type 2 diabetes, Severity of Illness Index, Haplogroup, 0302 clinical medicine, Polymorphism (computer science), 10. No inequality, lcsh:Science, Aged, 80 and over, Multidisciplinary, Diabetic retinopathy, Middle Aged, Mitochondria, Phenotype, Female, Adult, medicine.medical_specialty, Adolescent, Genotype, Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, Macular Edema, White People, Article, Young Adult, 03 medical and health sciences, Internal medicine, Diabetes mellitus, medicine, Humans, Aged, Glycated Hemoglobin, Diabetic Retinopathy, business.industry, lcsh:R, Australia, Case-control study, medicine.disease, United Kingdom, eye diseases, Diabetes Mellitus, Type 1, 030104 developmental biology, Diabetes Mellitus, Type 2, Case-Control Studies, lcsh:Q, business, 030217 neurology & neurosurgery, Human mitochondrial DNA haplogroup

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d24796f4c0fbd3b73adca8cd063fcd3Test
http://link.springer.comTest/article/10.1038/s41598-018-37388-8

9

A dose-finding Phase 2 study of single agent isatuximab (anti-CD38 mAb) in relapsed/refractory multiple myeloma

المؤلفون: Ravi Vij, Claire Brillac, Jesús F. San-Miguel, Marielle Chiron, Corina Oprea, Parameswaran Hari, Nikoletta Lendvai, Jeffrey A. Zonder, Cristina Gasparetto, Thomas Martin, Joshua R. Richter, Meletios A. Dimopoulos, Joseph R. Mikhael, Eric Charpentier, William I. Bensinger, Enrique M. Ocio, Shaji Kumar, Craig E. Cole, Jonathan L. Kaufman

المساهمون: Universidad de Cantabria

المصدر: Leukemia . 2020 Dec;34(12):3298-3309
Leukemia
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, Nausea, Phases of clinical research, Myeloma, Cancer immunotherapy, Proteasome inhibitors, Relapsed/refractory multiple myeloma, Antibodies, Monoclonal, Humanized, Gastroenterology, Article, Refractory, Internal medicine, Isatuximab (anti-CD38 mAb), medicine, Humans, Progression-free survival, Adverse effect, Multiple myeloma, Aged, Isatuximab, Aged, 80 and over, business.industry, Phase 2 study, Hematology, Middle Aged, medicine.disease, ADP-ribosyl Cyclase 1, Progression-Free Survival, Oncology, Monoclonal, Female, medicine.symptom, Neoplasm Recurrence, Local, business, Multiple Myeloma, Multiple myeloma gammopathies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e9b9e34babe8d3899acf31fcaaf4f0Test
http://hdl.handle.net/10902/21543Test

10

Deregulation of Notch1 pathway and circulating endothelial progenitor cell (EPC) number in patients with bicuspid aortic valve with and without ascending aorta aneurysm

المؤلفون: Maurizio Forte, Carmela Rita Balistreri, Floriana Crapanzano, Giovanni Ruvolo, Antonino G.M. Marullo, Leonardo Schirone, Sebastiano Sciarretta, Elena Cavarretta, Alberto Allegra, Calogera Pisano, Giacomo Frati, Ernesto Greco

المساهمون: Balistreri, Carmela R, Crapanzano, Floriana, Schirone, Leonardo, Allegra, Alberto, Pisano, Calogera, Ruvolo, Giovanni, Forte, Maurizio, Greco, Ernesto, Cavarretta, Elena, Marullo, Antonino G M, Sciarretta, Sebastiano, Frati, Giacomo

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Aortic valve, Notch1 signaling pathwat, Heart Valve Diseases, 030204 cardiovascular system & hematology, Aortic aneurysm, 0302 clinical medicine, Bicuspid aortic valve, Bicuspid Aortic Valve Disease, Notch Signaling Pathway, circulating EPC populations, Receptor, Notch1, Receptor, Aorta, Endothelial Progenitor Cells, Aged, 80 and over, Multidisciplinary, Middle Aged, Aortic Aneurysm, medicine.anatomical_structure, Aortic Valve, cardiovascular system, Cardiology, Medicine, Female, Tricuspid Valve, Signal Transduction, Adult, medicine.medical_specialty, Endothelial Progenitor Cells (EPC), Science, Notch signaling pathway, Bicuspid Aortic Valve (BAV), Endothelial progenitor cell, Article, ascending aortic aneurysm, 03 medical and health sciences, Internal medicine, medicine, Humans, In patient, cardiovascular diseases, Progenitor cell, Notch 1 signaling pathway, Aged, Tricuspid Aortic Valve (TAV), Ascending Aorta Aneurysm (AAA), business.industry, Settore MED/23 - Chirurgia Cardiaca, medicine.disease, 030104 developmental biology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02570d12956e56704191679d2fc88b35Test
http://hdl.handle.net/11573/1212445Test

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