نتائج البحث

1

Combination of anti-PD-1 antibody with P-GEMOX as a potentially effective immunochemotherapy for advanced natural killer/T cell lymphoma

المؤلفون: Yan Gao, Jun Cai, Yi Xia, Qingqing Cai, Shuyun Ma, Yuchen Zhang, Lirong Li, Xiaopeng Tian, Hang Yang, Panpan Liu, Yajun Li, Xuanye Zhang, Hui Zhou, Huiqiang Huang

المصدر: Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-9 (2020)
Signal Transduction and Targeted Therapy

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Antibodies, Neoplasm, Programmed Cell Death 1 Receptor, lcsh:Medicine, Gastroenterology, Deoxycytidine, Polyethylene Glycols, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, T-cell lymphoma, lcsh:QH301-705.5, Middle Aged, Neoplasm Proteins, Lymphoma, Extranodal NK-T-Cell, Oxaliplatin, Survival Rate, 030220 oncology & carcinogenesis, Female, medicine.drug, Adult, medicine.medical_specialty, Drug development, GemOx, Neutropenia, Predictive markers, Article, Disease-Free Survival, 03 medical and health sciences, Fluorodeoxyglucose F18, Internal medicine, Genetics, medicine, Asparaginase, Humans, Survival rate, Aged, Pegaspargase, Haematological cancer, business.industry, lcsh:R, medicine.disease, Gemcitabine, Regimen, 030104 developmental biology, lcsh:Biology (General), Positron-Emission Tomography, business, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aa20c22427d24bef448ec18145aa9bTest
https://doaj.org/article/99ff2da0b38046018a5c7ce878c81a7fTest

2

Effect of drug metabolizing enzymes and transporters in Thai colorectal cancer patients treated with irinotecan-based chemotherapy

المؤلفون: Apichaya Puangpetch, Phichai Chansriwong, Ekaphop Sirachainan, Suwannee Sirilerttrakul, Chonlaphat Sukasem, Monpat Chamnanphon, Thanyanan Reungwetwattana, Chalirmporn Atasilp

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Genetic testing, Colorectal cancer, lcsh:Medicine, 0302 clinical medicine, Gene Frequency, Genetics research, Cytochrome P-450 CYP3A, Glucuronosyltransferase, lcsh:Science, Multidisciplinary, Molecular medicine, Middle Aged, Thailand, Multidrug Resistance-Associated Protein 2, Population study, Female, Multidrug Resistance-Associated Proteins, Colorectal Neoplasms, medicine.drug, Adult, medicine.medical_specialty, Neutropenia, Genotype, Irinotecan, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, CYP3A5, Allele frequency, Alleles, Aged, Polymorphism, Genetic, business.industry, lcsh:R, Genetic Variation, Membrane Transport Proteins, medicine.disease, Personalized medicine, Genotype frequency, 030104 developmental biology, Genetic markers, DPYD, ATP-Binding Cassette Transporters, lcsh:Q, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd7951ea617b032dfd1c624b20a74d5Test
http://link.springer.com/article/10.1038/s41598-020-70351-0Test

3

Functional and morphological cardiovascular alterations associated with neurofibromatosis 1

المؤلفون: Antonio Cutruzzolà, Concetta Irace, Agostino Gnasso, Jolanda Sabatino, Salvatore De Rosa, Ciro Indolfi, Rosa Gullace, Carmen Spaccarotella, Daniela Concolino, Marco Frazzetto

المساهمون: Cutruzzola, A., Irace, C., Frazzetto, M., Sabatino, J., Gullace, R., De Rosa, S., Spaccarotella, C., Concolino, D., Indolfi, C., Gnasso, A.

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Blood viscosity, Hemodynamics, lcsh:Medicine, 030204 cardiovascular system & hematology, 0302 clinical medicine, Cardiovascular Disease, Brachial artery, lcsh:Science, Multidisciplinary, Heart Function Test, Middle Aged, Blood Viscosity, Peripheral, Carotid Arteries, Cardiovascular Diseases, Heart Function Tests, Cardiology, Female, Carotid artery structure, Disease Susceptibility, Human, Adult, Carotid Arterie, Cardiac function curve, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Neurofibromatosis 1, Adolescent, Ischemia, Article, Young Adult, 03 medical and health sciences, Internal medicine, medicine.artery, medicine, Humans, Hemodynamic, Neurofibromatosis, business.industry, lcsh:R, Biomarker, medicine.disease, nervous system diseases, 030104 developmental biology, Risk factors, Biomarkers, lcsh:Q, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c1ae4921a393ac7cd1e4f1c10ec6efTest
http://link.springer.com/article/10.1038/s41598-020-68908-0Test

4

The Prognostic Value of Deficient Mismatch Repair in Stage II–IVa Nasopharyngeal Carcinoma in the Era of IMRT

المؤلفون: Jian-fang Gao, Hong-xing Kan, Yun-Xiang Zhang, Ming-chen Wang, Ya-nan Zhang, Shi-geng Zhang, Ya-ting Zhang, Fu-Rong Hao, Fang-ming Chen, Han Li, Cheng Li, Yang Li, Xiu-feng Li, Hao Ma, Xiao-li Wang

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Biopsy, medicine.medical_treatment, lcsh:Medicine, DNA Mismatch Repair, 0302 clinical medicine, PMS2, Stage (cooking), Child, lcsh:Science, Cancer, Mismatch Repair Endonuclease PMS2, Aged, 80 and over, Nasopharyngeal Carcinoma, Multidisciplinary, Middle Aged, Prognosis, DNA-Binding Proteins, MutS Homolog 2 Protein, 030220 oncology & carcinogenesis, Female, MutL Protein Homolog 1, Adult, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, Adolescent, Article, Disease-Free Survival, Young Adult, 03 medical and health sciences, Medical research, Internal medicine, medicine, Humans, Aged, Neoplasm Staging, Proportional hazards model, business.industry, lcsh:R, Nasopharyngeal Neoplasms, medicine.disease, digestive system diseases, Radiation therapy, MSH6, 030104 developmental biology, Nasopharyngeal carcinoma, MSH2, lcsh:Q, Radiotherapy, Intensity-Modulated, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d767a9c5809441e5e350293f161468b0Test
http://link.springer.com/article/10.1038/s41598-020-66678-3Test

5

The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia

المؤلفون: Yabo Ouyang, Dexi Chen, Lijun Pang, Xianghua Guo, Ronghua Jin, Jiming Yin, Ying-Mei Feng, Hongbo Shi, Honglin Shi, Wenjing Wang, Luxin Qiao

المصدر: Cell Death and Disease, Vol 11, Iss 6, Pp 1-8 (2020)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Lymphocyte, CD8-Positive T-Lymphocytes, 0302 clinical medicine, STAT5 Transcription Factor, Cytotoxic T cell, IL-2 receptor, Aged, 80 and over, lcsh:Cytology, Middle Aged, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Female, Coronavirus Infections, medicine.drug, Interleukin 2, Adult, medicine.medical_specialty, T cell, Critical Illness, Immunology, Pneumonia, Viral, Peripheral blood mononuclear cell, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Betacoronavirus, Immune system, Internal medicine, medicine, Humans, Lymphocyte Count, lcsh:QH573-671, Pandemics, Aged, business.industry, SARS-CoV-2, Interleukins, Tumor Suppressor Proteins, Interleukin-2 Receptor alpha Subunit, COVID-19, Cell Biology, Janus Kinase 1, medicine.disease, Pneumonia, 030104 developmental biology, Viral infection, Interleukin-2, business, CD8

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54f768432e3b5857a30940e825993ceTest
http://link.springer.com/article/10.1038/s41419-020-2636-4Test

6

Multiplexed MRM-based protein quantification of putative prognostic biomarkers for chronic kidney disease progression in plasma

المؤلفون: Àngel Argilés, Vasiliki Lygirou, Eleni Petra, Flore Duranton, Harald Mischak, Manousos Makridakis, Jerome Zoidakis, Szymon Filip, Antonia Vlahou, Georgia Kontostathi, Rafael Stroggilos

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, 030232 urology & nephrology, lcsh:Medicine, Disease, Mass Spectrometry, Cohort Studies, Prognostic markers, 0302 clinical medicine, Multiplex, Longitudinal Studies, lcsh:Science, Aged, 80 and over, Multidisciplinary, Immunoglobulin heavy constant alpha 1, Middle Aged, Prognosis, Blood proteins, Hemoglobin Subunits, Disease Progression, Female, medicine.symptom, Complement C1 Inhibitor Protein, Glomerular Filtration Rate, Adult, medicine.medical_specialty, Quantitative proteomics, Proteomic analysis, Renal function, Article, 03 medical and health sciences, Internal medicine, Alpha-Globulins, medicine, Humans, Renal Insufficiency, Chronic, Aged, business.industry, lcsh:R, medicine.disease, 030104 developmental biology, Albuminuria, Muramidase, lcsh:Q, beta 2-Microglobulin, business, Biomarkers, Follow-Up Studies, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45ed4d3b1c70609a58b348a2d897aa9Test
http://link.springer.com/article/10.1038/s41598-020-61496-zTest

7

Human T-lymphotropic virus 1 and 2 among people who used illicit drugs in the state of Pará, northern Brazil

المؤلفون: Ricardo Ishak, Andreia Polliana Castro de Souza, Aldemir B. Oliveira-Filho, Emil Kupek, Luisa Caricio Martins, Gláucia C. Silva-Oliveira, Luiz Fernando Almeida Machado, José Alexandre Rodrigues de Lemos, Camila Moraes Gomes, Antonio Carlos Rosário Vallinoto, Benedikt Fischer, Ana Paula Sousa Araújo

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Adolescent, Epidemiology, viruses, 030106 microbiology, Population, Unprotected sex, lcsh:Medicine, Article, Virus, Drug Users, Young Adult, 03 medical and health sciences, Health services, Environmental health, Prevalence, Humans, Medicine, education, lcsh:Science, High rate, Human T-lymphotropic virus 1, education.field_of_study, Multidisciplinary, High prevalence, biology, Illicit Drugs, business.industry, Human T-lymphotropic virus 2, lcsh:R, HTLV, biology.organism_classification, HTLV-I Infections, Cross-Sectional Studies, 030104 developmental biology, Risk factors, Viral infection, HTLV-II Infections, Female, lcsh:Q, business, Brazil

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c209f3f25161845b7d27205b27abb7aTest
http://link.springer.com/article/10.1038/s41598-019-51383-7Test

8

High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes

المؤلفون: Paul J. Thornalley, Naila Rabbani, Antonysunil Adaikalakoteswari, Nancy Cardinez, Bruce A. Perkins, Andrew J. Weston, Justin A. Lee, Leif E. Lovblom

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports

مصطلحات موضوعية: Adult, Glycation End Products, Advanced, Male, 0301 basic medicine, medicine.medical_specialty, type 1 diabetes, Science, Renal function, 030209 endocrinology & metabolism, Biochemistry, Article, Diabetic nephropathy, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tandem Mass Spectrometry, Glycation, Internal medicine, medicine, Albuminuria, Humans, Diabetic Nephropathies, Prospective Studies, Pentosidine, Creatinine, Kidney, Multidisciplinary, business.industry, Middle Aged, medicine.disease, glycation adducts, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Advanced Oxidation Protein Products, chemistry, Case-Control Studies, Medicine, Female, Microalbuminuria, business, Biomarkers, Chromatography, Liquid, Glomerular Filtration Rate

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e6b8b0abb1c620cf6e7f259b74c8c4Test
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85088690162&origin=inwardTest

9

Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia

المؤلفون: Sampada Kallol, Susana Contreras-Duarte, Jaime Gutiérrez, Andrea Leiva, Bárbara Fuenzalida, Lorena Carvajal, Christiane Albrecht, Valentina Pasten, Claudette Cantin

المصدر: Fuenzalida, Bárbara; Cantin, Claudette; Kallol, Sampada; Carvajal, Lorena; Pastén, Valentina; Contreras-Duarte, Susana; Albrecht, Christiane; Gutierrez, Jaime; Leiva, Andrea (2020). Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia. Scientific Reports, 10(1), p. 5264. Nature Publishing Group 10.1038/s41598-020-61629-4 <http://dx.doi.org/10.1038/s41598-020-61629-4Test>
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein B, Placenta, lcsh:Medicine, 030204 cardiovascular system & hematology, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, lcsh:Science, 610 Medicine & health, Maternal-Fetal Exchange, Cells, Cultured, ATP Binding Cassette Transporter, Subfamily G, Member 1, Multidisciplinary, biology, medicine.diagnostic_test, Middle Aged, Fetal Blood, Trophoblasts, Cholesterol, medicine.anatomical_structure, ABCG1, embryonic structures, Female, lipids (amino acids, peptides, and proteins), ATP Binding Cassette Transporter 1, Adult, Endocrine reproductive disorders, medicine.medical_specialty, Lipoproteins, Hypercholesterolemia, Article, Young Adult, 03 medical and health sciences, Syncytiotrophoblast, Internal medicine, medicine, Humans, Triglycerides, Dyslipidaemias, Apolipoprotein A-I, business.industry, lcsh:R, Infant, Newborn, Trophoblast, nutritional and metabolic diseases, Biological Transport, Pregnancy Complications, 030104 developmental biology, Endocrinology, Receptors, LDL, chemistry, ABCA1, LDL receptor, biology.protein, 570 Life sciences, lcsh:Q, Lipid profile, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fc3917882ccfda77e4b41df9170240Test

10

Presence of Histatin-1 in Human Tears and Association with Aqueous Deficient Dry Eye Diagnosis: A Preliminary Study

المؤلفون: Sandeep Jain, Dhara Shah, Kyung-No Son, Sushma Kalmodia, Bayasgalan Surenkhuu, Marwan Ali, Dingcai Cao, Bao-Shiang Lee, Arun Balasubramaniam, Vinay K. Aakalu

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba20d133ab1b1772de07f3d0e76af21fTest
http://link.springer.com/article/10.1038/s41598-019-46623-9Test

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