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المؤلفون: Sampada Kallol, Susana Contreras-Duarte, Jaime Gutiérrez, Andrea Leiva, Bárbara Fuenzalida, Lorena Carvajal, Christiane Albrecht, Valentina Pasten, Claudette Cantin
المصدر: Fuenzalida, Bárbara; Cantin, Claudette; Kallol, Sampada; Carvajal, Lorena; Pastén, Valentina; Contreras-Duarte, Susana; Albrecht, Christiane; Gutierrez, Jaime; Leiva, Andrea (2020). Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia. Scientific Reports, 10(1), p. 5264. Nature Publishing Group 10.1038/s41598-020-61629-4 <http://dx.doi.org/10.1038/s41598-020-61629-4Test>
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Apolipoprotein B, Placenta, lcsh:Medicine, 030204 cardiovascular system & hematology, chemistry.chemical_compound, 0302 clinical medicine, Pregnancy, lcsh:Science, 610 Medicine & health, Maternal-Fetal Exchange, Cells, Cultured, ATP Binding Cassette Transporter, Subfamily G, Member 1, Multidisciplinary, biology, medicine.diagnostic_test, Middle Aged, Fetal Blood, Trophoblasts, Cholesterol, medicine.anatomical_structure, ABCG1, embryonic structures, Female, lipids (amino acids, peptides, and proteins), ATP Binding Cassette Transporter 1, Adult, Endocrine reproductive disorders, medicine.medical_specialty, Lipoproteins, Hypercholesterolemia, Article, Young Adult, 03 medical and health sciences, Syncytiotrophoblast, Internal medicine, medicine, Humans, Triglycerides, Dyslipidaemias, Apolipoprotein A-I, business.industry, lcsh:R, Infant, Newborn, Trophoblast, nutritional and metabolic diseases, Biological Transport, Pregnancy Complications, 030104 developmental biology, Endocrinology, Receptors, LDL, chemistry, ABCA1, LDL receptor, biology.protein, 570 Life sciences, lcsh:Q, Lipid profile, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fc3917882ccfda77e4b41df9170240Test
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المؤلفون: Hiroshi Asahara, Yoshiaki Ito, Tokio Matsuzaki, Kohei Miyata, Tempei Sato, Martin Lotz, Ryo Nakamichi, Merissa Olmer, Eiji Sugiyama, Masafumi Inui, Sho Mokuda
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Cartilage, Articular, CRISPR-Cas9 genome editing, Knee Joint, Ubiquitylation, General Physics and Astronomy, Core Binding Factor Alpha 1 Subunit, 02 engineering and technology, Osteoarthritis, Menisci, Tibial, Mice, Ubiquitin, lcsh:Science, Aged, 80 and over, Mice, Knockout, Multidisciplinary, biology, Cartilage homeostasis, Chemistry, Middle Aged, 021001 nanoscience & nanotechnology, musculoskeletal system, Ubiquitin ligase, Cell biology, RUNX2, medicine.anatomical_structure, miRNAs, 0210 nano-technology, Signal Transduction, Adult, musculoskeletal diseases, Ubiquitin-Protein Ligases, Science, WWP2, macromolecular substances, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Young Adult, Downregulation and upregulation, medicine, Animals, Humans, RNA, Messenger, Aged, Cartilage, Skull, Ubiquitination, General Chemistry, X-Ray Microtomography, medicine.disease, Arthritis, Experimental, Disease Models, Animal, 030104 developmental biology, biology.protein, lcsh:Q, ADAMTS5 Protein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4c9bffffe46cfae2df3f937bdfb3f0Test
http://link.springer.com/article/10.1038/s41467-019-10177Test-1 -
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المؤلفون: Jiaze Tang, Yongzhang Luo, Yan Fu, Jie Liu, Siran Xu, Chunying Wang
المصدر: Cell Death and Disease, Vol 10, Iss 3, Pp 1-17 (2019)
Cell Death & Diseaseمصطلحات موضوعية: 0301 basic medicine, Male, Vascular Endothelial Growth Factor A, Cancer Research, Angiogenesis, Carcinogenesis, Chemokine receptor, chemistry.chemical_compound, Mice, 0302 clinical medicine, Phosphorylation, Receptor, Child, Melanoma, Aged, 80 and over, Mice, Inbred BALB C, Neovascularization, Pathologic, lcsh:Cytology, EIF4E, Middle Aged, beta-Arrestin 2, Vascular endothelial growth factor, Cell Transformation, Neoplastic, src-Family Kinases, 030220 oncology & carcinogenesis, Child, Preschool, Female, Proto-oncogene tyrosine-protein kinase Src, Signal Transduction, Adult, Adolescent, Immunology, Mice, Nude, Biology, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, Young Adult, medicine, Animals, Humans, lcsh:QH573-671, Aged, Cell Proliferation, Receptors, CXCR, Cell growth, Infant, Cell Biology, medicine.disease, Hypoxia-Inducible Factor 1, alpha Subunit, Mice, Inbred C57BL, 030104 developmental biology, Eukaryotic Initiation Factor-4E, HEK293 Cells, chemistry, A549 Cells, Tissue Array Analysis, Cancer research
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae68b42028eaad5bb9180990f2baab5Test
http://link.springer.com/article/10.1038/s41419-019-1442-3Test -
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المؤلفون: Chetan Bakshi, Veena Dhawan, Rajesh Vijayvergiya
المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-22 (2019)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Adult, Male, Macrophage polarization, Nitric Oxide Synthase Type II, lcsh:Medicine, Coronary Artery Disease, Biology, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, SOCS5, Humans, Promoter Regions, Genetic, lcsh:Science, Gene, Multidisciplinary, Interleukin-12 Subunit p40, Macrophages, lcsh:R, Promoter, Methylation, Janus Kinase 1, DNA Methylation, Middle Aged, M2 Macrophage, 030104 developmental biology, STAT1 Transcription Factor, chemistry, DNA methylation, Cancer research, Female, lcsh:Q, 030217 neurology & neurosurgery, DNA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42639de82cdde338f8f22b07ee0b5149Test
http://link.springer.com/article/10.1038/s41598-018-38040Test-1 -
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المؤلفون: Shu Ma, Yan Yu, Gen Xia Liu, Zilu Wang, Jinhua Yu, Yi Xiang Zhou, Yao Li, Ya Die Lu, Lin Jin
المصدر: Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-14 (2018)
Experimental & Molecular Medicineمصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Adult, Adolescent, MAP Kinase Signaling System, Cellular differentiation, medicine.medical_treatment, Clinical Biochemistry, lcsh:Medicine, Biochemistry, Models, Biological, Article, Receptor, IGF Type 1, lcsh:Biochemistry, 03 medical and health sciences, Young Adult, Dentin sialophosphoprotein, Osteogenesis, medicine, Humans, lcsh:QD415-436, Molecular Biology, 3' Untranslated Regions, Cells, Cultured, Dental Pulp, Cell Proliferation, biology, Chemistry, Growth factor, Mesenchymal stem cell, lcsh:R, Cell Differentiation, Mesenchymal Stem Cells, Receptors, Somatomedin, MicroRNAs, 030104 developmental biology, Phenotype, Gene Expression Regulation, Cancer cell, Osteocalcin, biology.protein, Cancer research, Molecular Medicine, Odontogenesis, RNA Interference, Dentin sialoprotein, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8010bb8db27555eec0b4d1664baf0fTest
https://doaj.org/article/b8aaa88404414c8880af93f5cef9345fTest -
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المؤلفون: Mariann I. Lassenius, Aila J. Ahola, Valma Harjutsalo, Per-Henrik Groop, Markku Lehto, Carol Forsblom
المساهمون: Clinicum, Department of Medicine, Nefrologian yksikkö, Research Programs Unit, Diabetes and Obesity Research Program, Per Henrik Groop / Principal Investigator
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Adult, Lipopolysaccharides, Male, medicine.medical_specialty, Intra-Abdominal Fat, PROTEIN, 030209 endocrinology & metabolism, LIPOPOLYSACCHARIDE, DISEASE, Article, SERUM, 03 medical and health sciences, chemistry.chemical_compound, LIPOPROTEINS, 0302 clinical medicine, Insulin resistance, Diabetes mellitus, Internal medicine, medicine, Humans, Adiposity, RISK, Inflammation, Type 1 diabetes, INSULIN-RESISTANCE, Multidisciplinary, Triglyceride, biology, business.industry, C-reactive protein, Middle Aged, medicine.disease, Obesity, 3. Good health, 030104 developmental biology, Endocrinology, C-Reactive Protein, Diabetes Mellitus, Type 1, chemistry, OBESITY, 3121 General medicine, internal medicine and other clinical medicine, biology.protein, lipids (amino acids, peptides, and proteins), Female, business, Dyslipidemia
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a9745abc64dc5b250d93e013b9a07eTest
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المؤلفون: Santanu Mandal, Shibendu Ghosh, Prabuddha Mukhopadhyay, Gourab Dutta Banik, Abhijit Maity, Manik Pradhan, Chiranjit Ghosh
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, endocrine system, Erythrocytes, endocrine system diseases, Adolescent, 030209 endocrinology & metabolism, Type 2 diabetes, Oxygen Isotopes, Article, Pathogenesis, 03 medical and health sciences, Young Adult, 0302 clinical medicine, immune system diseases, Carbonic anhydrase, medicine, Diagnostic biomarker, Humans, Child, Carbonic Anhydrases, chemistry.chemical_classification, Glycated Hemoglobin, Type 1 diabetes, Multidisciplinary, Isotope, biology, nutritional and metabolic diseases, Metabolism, Carbon Dioxide, Middle Aged, medicine.disease, Kinetics, 030104 developmental biology, Enzyme, Diabetes Mellitus, Type 1, chemistry, Biochemistry, Breath Tests, Diabetes Mellitus, Type 2, Spectrophotometry, Case-Control Studies, Child, Preschool, Isotope Labeling, biology.protein, Female
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47f260f9292443b5f5509b2ee187cc7Test
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المؤلفون: C. Fei, Sida Zhao, Qingqing Zheng, Juan Guo, Xiao Li, Y. Zhao, Chunkang Chang
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, MMP1, p38 mitogen-activated protein kinases, Down-Regulation, Biology, Matrix metalloproteinase, Hydroxamic Acids, Article, Pathogenesis, 03 medical and health sciences, Young Adult, Downregulation and upregulation, hemic and lymphatic diseases, Cell Line, Tumor, Humans, Aged, Cell Proliferation, Aged, 80 and over, Multidisciplinary, Cell growth, Chemistry, Mesenchymal stem cell, Mesenchymal Stem Cells, Hematology, Middle Aged, 030104 developmental biology, Oncology, Cell culture, Apoptosis, Myelodysplastic Syndromes, Cancer research, Female, RNA Interference, Matrix Metalloproteinase 1, Oligopeptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::484f405936e73ed59d8321eaae45b5b8Test
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المؤلفون: Ying-Hong Shi, Zhi Dai, Lei Yu, Jie Hu, Ya Cao, Dong-Mei Gao, Dan Yin, Yong Zhang, Zheng Wang, Jian Zhou, Cheng Jin, Qing Chen, Zheng-Jun Zhou, Jia Fan, Shao-Lai Zhou, Xue-Dong Li
المصدر: Cell Death & Disease
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Carcinoma, Hepatocellular, Immunology, Biology, Epigenesis, Genetic, Mixed Function Oxygenases, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, 0302 clinical medicine, Suppressor of Cytokine Signaling 1 Protein, Downregulation and upregulation, Proto-Oncogene Proteins, Gene silencing, Animals, Humans, Epigenetics, Neoplasm Metastasis, Aged, 5-Hydroxymethylcytosine, Suppressor of cytokine signaling 1, Liver Neoplasms, Cell Biology, DNA Methylation, Middle Aged, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, MicroRNAs, 030104 developmental biology, DNA demethylation, chemistry, Matrix Metalloproteinase 9, 030220 oncology & carcinogenesis, DNA methylation, Cancer research, 5-Methylcytosine, Original Article, Female, Chromatin immunoprecipitation, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7210bac8bdad9d3b448b996af66ea34Test
http://europepmc.org/articles/PMC5520877Test -
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المؤلفون: Sung Woo Kim, Gwon-Soo Jung, Inkyu Lee, Jun-Kyu Byun, Soo-Young Park, Keun-Gyu Park, Yu Na Kang, Sungwoo Lee, Se Young Jang, Yeon-Kyung Choi, Mi-Kyung Kim, Eui-Cheol Shin, Jae-Han Jeon
المصدر: Scientific Reports
SCIENTIFIC REPORTS(6)مصطلحات موضوعية: 0301 basic medicine, Adult, Pyruvate dehydrogenase kinase, Hepacivirus, Biology, Protein Serine-Threonine Kinases, Virus Replication, Antiviral Agents, Article, Cell Line, Serine, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biosynthesis, Downregulation and upregulation, Glucokinase, Ribavirin, Humans, Glycolysis, Aged, Multidisciplinary, Dichloroacetic Acid, virus diseases, Interferon-alpha, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Azepines, Middle Aged, Triazoles, Hypoxia-Inducible Factor 1, alpha Subunit, digestive system diseases, 030104 developmental biology, Biochemistry, Viral replication, chemistry, Liver, Anaerobic glycolysis, 030220 oncology & carcinogenesis, Hepatocytes, RNA Interference
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd5f858926f08bb2d89b1d9ba8d3ab8Test