التفاصيل البيبلوغرافية
العنوان:
An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis
المؤلفون:
Jun Liu , Elena Carnero-Montoro , Jenny van Dongen , Samantha Lent , Ivana Nedeljkovic , Symen Ligthart , Pei-Chien Tsai , Tiphaine C. Martin , Pooja R. Mandaviya , Rick Jansen , Marjolein J. Peters , Liesbeth Duijts , Vincent W. V. Jaddoe , Henning Tiemeier , Janine F. Felix , Gonneke Willemsen , Eco J. C. de Geus , Audrey Y. Chu , Daniel Levy , Shih-Jen Hwang , Jan Bressler , Rahul Gondalia , Elias L. Salfati , Christian Herder , Bertha A. Hidalgo , Toshiko Tanaka , Ann Zenobia Moore , Rozenn N. Lemaitre , Min A Jhun , Jennifer A. Smith , Nona Sotoodehnia , Stefania Bandinelli , Luigi Ferrucci , Donna K. Arnett , Harald Grallert , Themistocles L. Assimes , Lifang Hou , Andrea Baccarelli , Eric A. Whitsel , Ko Willems van Dijk , Najaf Amin , André G. Uitterlinden , Eric J. G. Sijbrands , Oscar H. Franco , Abbas Dehghan , Tim D. Spector , Josée Dupuis , Marie-France Hivert , Jerome I. Rotter , James B. Meigs , James S. Pankow , Joyce B. J. van Meurs , Aaron Isaacs , Dorret I. Boomsma , Jordana T. Bell , Ayşe Demirkan , Cornelia M. van Duijn
المصدر:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
بيانات النشر:
Nature Portfolio, 2019.
سنة النشر:
2019
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Our understanding of the functional link between differential DNA methylation and type 2 diabetes and obesity remains limited. Here the authors present a blood-based EWAS of fasting glucose and insulin among 4808 non-diabetic Europeans and identify nine CpGs not previously implicated in glucose, insulin homeostasis and diabetes.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-019-10487-4
الوصول الحر:
https://doaj.org/article/19891659495247948d3d723f24545dddTest
رقم الانضمام:
edsdoj.19891659495247948d3d723f24545ddd
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