The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage
| العنوان: | The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage |
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| المؤلفون: | Joana Díaz-Gómez, Changfu Zhu, Teresa Capell, Carmina Nogareda, Richard M. Twyman, Manuel Portero-Otin, Gerhard Sandmann, José C. E. Serrano, Jose A. Moreno, Eduardo Angulo, Paul Christou |
| المصدر: | Repositorio Abierto de la UdL Universitad de Lleida Recercat. Dipósit de la Recerca de Catalunya instname Scientific Reports |
| بيانات النشر: | Nature, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, chemistry.chemical_classification, Absorption (pharmacology), 030109 nutrition & dietetics, Multidisciplinary, Animal feed, organic chemicals, Biofortification, Retinol, food and beverages, macromolecular substances, Health benefits, Biology, Article, biological factors, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Botany, polycyclic compounds, Composition (visual arts), Dietary nutrients, Food science, Carotenoid |
| الوصف: | Carotenoids are important dietary nutrients with health-promoting effects. The biofortification of staple foods with carotenoids provides an efficient delivery strategy but little is known about the fate and distribution of carotenoids supplied in this manner. The chicken provides a good model of human carotenoid metabolism so we supplemented the diets of laying hens using two biofortified maize varieties with distinct carotenoid profiles and compared the fate of the different carotenoids in terms of distribution in the feed, the hen’s livers and the eggs. We found that after a period of depletion, pro-vitamin A (PVA) carotenoids were preferentially diverted to the liver and relatively depleted in the eggs, whereas other carotenoids were transported to the eggs even when the liver remained depleted. When retinol was included in the diet, it accumulated more in the eggs than the livers, whereas PVA carotenoids showed the opposite profile. Our data suggest that a transport nexus from the intestinal lumen to the eggs introduces bottlenecks that cause chemically-distinct classes of carotenoids to be partitioned in different ways. This nexus model will allow us to optimize animal feed and human diets to ensure that the health benefits of carotenoids are delivered in the most effective manner. This research was supported by grants PIM2010PKB-00746 CAROMAIZE, from Ministerio de Economia y Competitividad (MINECO) Spain; RecerCaixa PC084082; and European Research Council IDEAS Proof of Concept Program Multinutrient Maize (to PC). |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dc84c68609b435ac622a28f3d4434dTest http://hdl.handle.net/10459.1/58475Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....17dc84c68609b435ac622a28f3d4434d |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |