المصدر: Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

الوصول الحر: https://clinicaltrials.gov/show/NCT02644512Test

Other URLs: http://clinicalstudies.info.nih.gov/cgi/detail.cgi?A_2016-C-0043.htmlTest

المصدر: Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT06222203Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?B_001696-C.htmlTest

المصدر: Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Phase III Randomized Controlled Trial

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT05361811Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?A_000657-C.htmlTest

المصدر: Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical Trial

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT04879160Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?B_000173-C.htmlTest

المصدر: Incidence of Malignant Peripheral Nerve Sheath Tumors Development in Patients With Neurofibromatosis Type 1 Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT04774289Test

المصدر: A Phase 0/I/II Study of the Cyclin-Dependent Kinase(CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type 1 (NF1) Related Atypical Neurofibromas

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT04750928Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?A_2021-C-0011.htmlTest

المساهمون: Staci Peron, Ph.D., Principal Investigator

المصدر: Pilot Study of Medication Adherence in Children, Adolescents, and Adults With Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT03531814Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?B_2018-C-0093.htmlTest

المصدر: A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Patients With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT03109301Test

المساهمون: Brigitte Widemann, M.D., Dr. Brigitte Widemann, M.D.

المصدر: Ca WC, Stuart RW, Lefkowz DL, Starnes JD, Margol S, Lefkowz SS. hn of tumor necros factor and subsequent endotox shock by pfenone. t J munopharmacol. 1998 Dec;20(12):685-95. do 10.1016/s0192-0561(98)00042-3.
DeClue JE, Heffelfger S, Benvenuto G, Lg B, LS, RuW, Vass WC, Vkoch D, Ratner N. Epermal growth factor receptor expressn neurofromatos type 1-related tumors and NF1 anal models. J Cl vest. 2000 May;105(9):1233-41. do 10.1172/JC610.
Evans DG, Baser ME, McGaughran J, Shar S, Howard E, Moran A. Malnant perheral nerve sheath tumours neurofromatos 1. J Med Genet. 2002 May;39(5):311-4. do 10.1136/jmg.39.5.311.
Widemann BC, Babovic-Vuksanovic D, Dombi E, Wolters PL, Goldman S, Martin S, Goodwin A, Goodspeed W, Kieran MW, Cohen B, Blaney SM, King A, Solomon J, Patronas N, Balis FM, Fox E, Steinberg SM, Packer RJ. Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas. Pediatr Blood Cancer. 2014 Sep;61(9):1598-602. doi: 10.1002/pbc.25041. Epub 2014 Apr 22.
Phase II Trial of Pirfenidone in Children, Adolescents, and Young Adults With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT00076102Test

المصدر: A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

الوصول الحر: https://clinicaltrials.gov/ct2/show/NCT01362803Test

Other URLs: https://clinicalstudies.info.nih.gov/cgi/detail.cgi?B_2011-C-0161.htmlTest