يعرض 1 - 2 نتائج من 2 نتيجة بحث عن '"integrin-linked kinase"', وقت الاستعلام: 1.20s تنقيح النتائج
  1. 1
    دورية أكاديمية
    ATP allosterically stabilizes integrin-linked kinase for efficient force generation

    المؤلفون: Martin, Isabel M., Nava, Michele M., Wickström, Sara A., Graeter, Frauke

    المساهمون: STEMM - Stem Cells and Metabolism Research Program, Helsinki Institute of Life Science HiLIFE, University of Helsinki

    مصطلحات موضوعية: focal adhesion, integrin-linked kinase, molecular dynamics, traction force microscopy, STRUCTURAL BASIS, THERAPEUTIC TARGET, CELL-ADHESION, ALPHA-PARVIN, ILK, DOMAIN, PINCH, KINDLIN-2, BINDING, LOCALIZATION, 1182 Biochemistry, cell and molecular biology

    وصف الملف: application/pdf

    العلاقة: We acknowledge Anu M. Luoto for technical assistance. This work was supported by the Klaus Tschira Foundation; the state of BadenWurttemberg through bwHPC; the German Research Foundation through Grant INST 35/1134-1 FUGG (to F.G.); the Helsinki Institute of Life Science; the Sigrid Juselius Foundation; and Academy of Finland Grant 317597 (to S.A.W.). Molecular graphics and analyses were partially performed with UCSF Chimera, developed by the Resource for Biocomputing, Visualization, and Informatics at the University of California San Francisco, with support from NIH Grant P41GM103311.; Martin , I M , Nava , M M , Wickström , S A & Graeter , F 2022 , ' ATP allosterically stabilizes integrin-linked kinase for efficient force generation ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 119 , no. 11 , 2106098119 . https://doi.org/10.1073/pnas.2106098119Test; ORCID: /0000-0001-8733-6364/work/117949109; ORCID: /0000-0001-6383-6292/work/156156175; http://hdl.handle.net/10138/347201Test; 27c74b8b-7cd2-4e16-9d73-a1a064961395; 000771757800001

    الإتاحة: http://hdl.handle.net/10138/347201Test

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  2. 2
    دورية أكاديمية
    Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network.

    المؤلفون: Holmes, Kristen M.1, Annala, Matti2, Chua, Corrine Y. X.1, Dunlap, Sarah M.1, Yuexin Liu1, Hugen, Niek1, Moore, Lynette M.1, Cogdell, David1, Limei Hu1, Nykter, Matti2, Hess, Kenneth3, Fuller, Gregory N.1, Wei Zhang1

    المصدر: Proceedings of the National Academy of Sciences of the United States of America. 2/28/2012, Vol. 109 Issue 9, p3475-3480. 6p.

    مصطلحات موضوعية: *INSULIN-like growth factor-binding proteins, *INTEGRIN-linked kinase, *GLIOMAS, *NEUROGLIA, *MUCOCILIARY system, *PATIENTS

    النص الكامل

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