دورية أكاديمية

Structure-based design of selective and potent G quadruplex-mediated telomarase inhibitors.

التفاصيل البيبلوغرافية
العنوان: Structure-based design of selective and potent G quadruplex-mediated telomarase inhibitors.
المؤلفون: Reed, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David., Kelland, Lloyd R., Neidle, Stephen
المصدر: Proceedings of the National Academy of Sciences of the United States of America; 04/24/2001, Vol. 98 Issue 9, p4844, 6p, 3 Color Photographs, 2 Diagrams, 4 Charts, 2 Graphs
مصطلحات موضوعية: TELOMERASE, CHEMICAL inhibitors
مستخلص: Describes the design of selective and potent G quadruplex-mediated telomerase inhibitors. Application in human cancers; Predictions of how trisubstituted acridine inhibitors will interact selectively with human DNA quadruplex structure.
قاعدة البيانات: Complementary Index