التفاصيل البيبلوغرافية
العنوان: |
Structure-based design of selective and potent G quadruplex-mediated telomarase inhibitors. |
المؤلفون: |
Reed, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David., Kelland, Lloyd R., Neidle, Stephen |
المصدر: |
Proceedings of the National Academy of Sciences of the United States of America; 04/24/2001, Vol. 98 Issue 9, p4844, 6p, 3 Color Photographs, 2 Diagrams, 4 Charts, 2 Graphs |
مصطلحات موضوعية: |
TELOMERASE, CHEMICAL inhibitors |
مستخلص: |
Describes the design of selective and potent G quadruplex-mediated telomerase inhibitors. Application in human cancers; Predictions of how trisubstituted acridine inhibitors will interact selectively with human DNA quadruplex structure. |
قاعدة البيانات: |
Complementary Index |