المؤلفون: Colúm Connolly, Clemens Steegborn, Donald C. Lo, Albena T. Dinkova-Kostova, Andrew Snyder, Vanita Chopra, Alexei Degterev, Michael A. Schwarzschild, Cho Low, Ulrike Träger, Leslie M. Thompson, Michael J. Van Kanegan, James R. Miller, Matthew Fuszard, Ningzhe Zhang, Ellen Sapp, Susanta Samajdar, Lisa Meisel, Kimberly B. Kegel-Gleason, Petr Vodicka, Adelaide Tousley, Lisa M. Ellerby, David Llères, Sébastien Moniot, Aleksey G. Kazantsev, Steven M. Hersch, Lisa A. Crawford, Ross S. Stein, Sarah J. Tabrizi, Eranthie Weerapana, Vijay Potluri, Linda S. Kaltenbach, Ruth Farmer, Blair R. Leavitt, Maureen Higgins, Luisa Quinti, Marian DiFiglia, Sharadha Dayalan Naidu, Xiqun Chen

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 23

مصطلحات موضوعية: 0301 basic medicine, Huntington's Disease, Male, Protein Conformation, Neurodegenerative, Inbred C57BL, environment and public health, Mice, Neural Stem Cells, NRF2 inducer, 2.1 Biological and endogenous factors, Aetiology, Cells, Cultured, Multidisciplinary, Cultured, Kelch-Like ECH-Associated Protein 1, biology, Microglia, Signal transducing adaptor protein, Brain, Middle Aged, respiratory system, Neural stem cell, Ubiquitin ligase, Cell biology, medicine.anatomical_structure, Huntington Disease, Neuroprotective Agents, Biochemistry, PNAS Plus, Cytokines, Female, Signal transduction, KEAP1/NRF2/ARE signaling, Huntington’s disease, Signal Transduction, Adult, antiinflammatory responses, NF-E2-Related Factor 2, Cells, 1.1 Normal biological development and functioning, digestive system, Proinflammatory cytokine, 03 medical and health sciences, Rare Diseases, Huntington's disease, Clinical Research, Underpinning research, medicine, Genetics, Animals, Humans, Transcription factor, Aged, Animal, Macrophages, Neurosciences, MPTP Poisoning, medicine.disease, Stem Cell Research, Brain Disorders, Rats, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, human neural stem cells, HEK293 Cells, Disease Models, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bba6be10075b3b40875d35cd1e72bd7Test
https://researchonline.lshtm.ac.uk/id/eprint/3931063/1/KEAP1.pdfTest

المؤلفون: Ying Zhang, Tatiana Boronina, Robert N. Cole, Paul Talalay, Yousang Hwang, Xiu Jun Wang, Albena T. Dinkova-Kostova, Katherine K. Stephenson, Hua Liu, Philip A. Cole, Young Hoon Ahn

مصطلحات موضوعية: Stereochemistry, Cell Survival, Electrons, Nitric Oxide, Cell Line, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Isothiocyanates, medicine, Structure–activity relationship, Animals, Sulfhydryl Compounds, Enzyme inducer, Adaptor Proteins, Signal Transducing, Skin, Biological Products, Multidisciplinary, Natural product, Kelch-Like ECH-Associated Protein 1, biology, Molecular Structure, Chemistry, Macrophages, Biological Sciences, Thiocarbamate, Cytoskeletal Proteins, Mechanism of action, Biochemistry, Sulfoxides, Isothiocyanate, biology.protein, medicine.symptom, Thiocyanates, Cysteine, Sulforaphane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23150210a23f3fa7928f294feee87a7Test
https://europepmc.org/articles/PMC2906893Test/

المؤلفون: Zachary R. Healy, Paul Talalay, Andrea L. Benedict, Jed W. Fahey, Albena T. Dinkova-Kostova, Christine Min, Scott L. Wehage

مصطلحات موضوعية: Adult, Male, Erythema, Ultraviolet Rays, Inflammation, Human skin, Biology, Toxicology, Direct DNA damage, chemistry.chemical_compound, Mice, Immune system, Isothiocyanates, medicine, Animals, Humans, Carcinogen, Skin, Multidisciplinary, integumentary system, fungi, Dose-Response Relationship, Radiation, Biological Sciences, Middle Aged, Dose–response relationship, chemistry, Sulfoxides, Cancer research, Female, medicine.symptom, Thiocyanates, Sulforaphane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1a9033e72276cec58a5a8ca1d69705Test
https://europepmc.org/articles/PMC2077285Test/