التفاصيل البيبلوغرافية
العنوان: |
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization. |
المؤلفون: |
Yang, F.-C., Atkinson, S.J., Gu, Y., Borneo, J.B., Roberts, A.W., Zheng, Y., Pennington, J., Williams, D.A. |
المصدر: |
Proceedings of the National Academy of Sciences of the United States of America; 05/08/2001, Vol. 98 Issue 10, p5614, 5p, 14 Black and White Photographs, 1 Diagram, 14 Graphs |
مصطلحات موضوعية: |
BONE marrow, HEMATOPOIETIC stem cells |
مستخلص: |
Studies the mechanism by which hematopoietic stem/progenitor (HSC/P) cells reconcile multiple external signals in the bone marrow microenvironment and migration between the bone marrow and the blood. Defective cell adhesion and enhanced mobilization exhibited by Rac2-deficient HSC/P cells; Hypermotility in vitro of Rac2-deficient HSC/P cells. |
قاعدة البيانات: |
Complementary Index |