دورية أكاديمية

Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization.

التفاصيل البيبلوغرافية
العنوان: Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization.
المؤلفون: Yang, F.-C., Atkinson, S.J., Gu, Y., Borneo, J.B., Roberts, A.W., Zheng, Y., Pennington, J., Williams, D.A.
المصدر: Proceedings of the National Academy of Sciences of the United States of America; 05/08/2001, Vol. 98 Issue 10, p5614, 5p, 14 Black and White Photographs, 1 Diagram, 14 Graphs
مصطلحات موضوعية: BONE marrow, HEMATOPOIETIC stem cells
مستخلص: Studies the mechanism by which hematopoietic stem/progenitor (HSC/P) cells reconcile multiple external signals in the bone marrow microenvironment and migration between the bone marrow and the blood. Defective cell adhesion and enhanced mobilization exhibited by Rac2-deficient HSC/P cells; Hypermotility in vitro of Rac2-deficient HSC/P cells.
قاعدة البيانات: Complementary Index
الوصف
تدمد:00278424
DOI:10.1073/pnas.101546898