دورية أكاديمية
The Role of Diabetic Choroidopathy in the Pathogenesis and Progression of Diabetic Retinopathy
| العنوان: | The Role of Diabetic Choroidopathy in the Pathogenesis and Progression of Diabetic Retinopathy |
|---|---|
| المؤلفون: | Scuderi L., Fragiotta S., Di Pippo M., Abdolrahimzadeh S. |
| المساهمون: | Scuderi, L., Fragiotta, S., Di Pippo, M., Abdolrahimzadeh, S. |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute (MDPI) ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND |
| سنة النشر: | 2023 |
| المجموعة: | Sapienza Università di Roma: CINECA IRIS |
| مصطلحات موضوعية: | choriocapillari, choroid, diabetes mellitu, diabetic choroidopathy, diabetic retinopathy, optical coherence tomography |
| الوصف: | Diabetic choroidopathy was first described on histopathological specimens of diabetic eyes. This alteration was characterized by the accumulation of PAS-positive material within the intracapillary stroma. Inflammation and polymorphonuclear neutrophils (PMNs) activation are crucial elements in choriocapillaris impairment. The evidence of diabetic choroidopathy in vivo was confirmed with multimodal imaging, which provides key quantitative and qualitative features to characterize the choroidal involvement. The choroid can be virtually affected in each vascular layer, from Haller’s layer to the choriocapillaris. However, the damage on the outer retina and photoreceptor cells is essentially driven by a choriocapillaris deficiency, which can be assessed through optical coherence tomography angiography (OCTA). The identification of characteristic features of diabetic choroidopathy can be significant for understanding the potential pathogenic and prognostic implications in diabetic retinopathy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/37373315; info:eu-repo/semantics/altIdentifier/wos/WOS:001014474700001; volume:24; issue:12; firstpage:1; lastpage:13; numberofpages:13; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11573/1688583Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85163959853 |
| DOI: | 10.3390/ijms241210167 |
| الإتاحة: | https://doi.org/10.3390/ijms241210167Test https://hdl.handle.net/11573/1688583Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.B60A5A4A |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/ijms241210167 |
|---|