التفاصيل البيبلوغرافية
| العنوان: |
Synthesis and Antioxidative Properties of 1,2,3,4-Tetrahydropyridine Derivatives with Different Substituents in 4-Position |
| المؤلفون: |
Daniele Aiello, Hendrik Jonas, Anna Carbone, Daniela Carbone, Camilla Pecoraro, Luisa Tesoriere, Jens Köhler, Bernhard Wünsch, Patrizia Diana |
| المصدر: |
Molecules; Volume 27; Issue 21; Pages: 7423 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
indicaxanthins, betalamic acid, antioxidant, dehydrobromination, TEMPO oxidation, (E)-(Z) configuration, piperidin-4-ones, cis / trans diastereomers, Wittig reaction, Lemieux – Johnson oxidation, Folin–Ciocalteu |
| جغرافية الموضوع: |
agris |
| الوصف: |
Natural products are an excellent source of inspiration for the development of new drugs. Among them, betalains have been extensively studied for their antioxidant properties and potential application as natural food dyes. Herein, we describe the seven-step synthesis of new betalamic acid analogs without carboxy groups in the 2- and 6-position with an overall yield of ~70%. The Folin–Ciocalteu assay was used to determine the antioxidant properties of protected intermediate 21. Additionally, the five-step synthesis of betalamic acid analog 35 with three ester moieties was performed. Using NMR techniques, the stability of the obtained compounds towards oxygen was analyzed. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Medicinal Chemistry; https://dx.doi.org/10.3390/molecules27217423Test |
| DOI: |
10.3390/molecules27217423 |
| الإتاحة: |
https://doi.org/10.3390/molecules27217423Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.359633B8 |
| قاعدة البيانات: |
BASE |
