دورية أكاديمية
Current indications of secondary enucleation in retinoblastoma management: A position paper on behalf of the european retinoblastoma group (EURbG)
| العنوان: | Current indications of secondary enucleation in retinoblastoma management: A position paper on behalf of the european retinoblastoma group (EURbG) |
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| المؤلفون: | Stathopoulos, Christina, Lumbroso Le Rouic, Livia, Moll, Annette C., Parulekar, Manoj, Maeder, Philippe, Doz, François, Jenkinson, Helen, Popovic, Maja Beck, Chantada, Guillermo Luis, Munier, Francis L. |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute |
| المجموعة: | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: | EXTERNAL BEAM IRRADIATION, INTRA-ARTERIAL CHEMOTHERAPY, INTRAVENOUS CHEMOTHERAPY, METASTASIS, RETINOBLASTOMA, SECONDARY ENUCLEATION, SURVIVAL, https://purl.org/becyt/ford/3.2Test, https://purl.org/becyt/ford/3Test |
| الوصف: | Secondary enucleation (SE) puts an irreversible end to eye-preserving therapies, whenever their prolongation is expected to violate the presumed state of metastatic grace. At present, it must be acknowledged that clear criteria for SE are missing, leading to empiric and subjective indications commonly related to disease progression or relapse, disease persistence masking the optic nerve head or treatment-related complications obscuring the fundus view. This absence of evidence-based consensus regarding SE is explained by the continuously moving frontiers of the conservative management as a result of diagnostic and therapeutic advances, as well as by the lack of studies sufficiently powered to accurately stratify the risk of metastasis in conservatively treated patients. In this position paper of the European Retinoblastoma Group (EURbG), we give an overview of the progressive shift in the indications for SE over the past decades and propose guidelines to assist decision-making with respect to when SE becomes imperative or recommended, with corresponding absolute and relative SE indications. Further studies and validation of biologic markers correlated with the risk of metastasis are expected to set more precisely the frontiers of conservative management and thus consensual criteria for SE in the future. ; Fil: Stathopoulos, Christina. Universite de Lausanne; Suiza ; Fil: Lumbroso Le Rouic, Livia. Institut Curie; Francia ; Fil: Moll, Annette C. Vrije Universiteit Amsterdam; Países Bajos ; Fil: Parulekar, Manoj. Birmingham Children's Hospital; Reino Unido ; Fil: Maeder, Philippe. Centre Hospitalier Universitaire Vaudois; Suiza ; Fil: Doz, François. Université de Paris; Francia ; Fil: Jenkinson, Helen. Birmingham Women’s and Children’s NHS Foundation Trust; Reino Unido ; Fil: Popovic, Maja Beck. Centre Hospitalier Universitaire Vaudois; Suiza ; Fil: Chantada, Guillermo Luis. Hospital Sant Joan de Deu Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina ; Fil: Munier, Francis L. ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6694 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2072-6694/13/14/3392Test; http://hdl.handle.net/11336/184217Test; Stathopoulos, Christina; Lumbroso Le Rouic, Livia; Moll, Annette C.; Parulekar, Manoj; Maeder, Philippe; et al.; Current indications of secondary enucleation in retinoblastoma management: A position paper on behalf of the european retinoblastoma group (EURbG); Multidisciplinary Digital Publishing Institute; Cancers; 13; 14; 7-2021; 1-18; CONICET Digital; CONICET |
| الإتاحة: | https://doi.org/10.3390/cancers13143392Test http://hdl.handle.net/11336/184217Test |
| حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by/2.5/arTest/ |
| رقم الانضمام: | edsbas.367D208F |
| قاعدة البيانات: | BASE |
| تدمد: | 20726694 |
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