التفاصيل البيبلوغرافية
| العنوان: |
Autophagy in HCV Replication and Protein Trafficking |
| المؤلفون: |
Ja Yeon Kim Chu, Jing-hsiung James Ou |
| المصدر: |
International Journal of Molecular Sciences; Volume 22; Issue 3; Pages: 1089 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2021 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
hepatitis C virus, autophagy, mitophagy, autophagosome biogenesis, HCV RNA replication, innate immunity, protein trafficking |
| جغرافية الموضوع: |
agris |
| الوصف: |
Autophagy is a catabolic process that is important for maintaining cellular homeostasis. It is also known to possess other functions including protein trafficking and anti-microbial activities. Hepatitis C virus (HCV) is known to co-opt cellular autophagy pathway to promote its own replication. HCV regulates autophagy through multiple mechanisms to control intracellular protein and membrane trafficking to enhance its replication and suppress host innate immune response. In this review, we discuss the current knowledge on the interplay between HCV and autophagy and the crosstalk between HCV-induced autophagy and host innate immune responses. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Molecular Immunology; https://dx.doi.org/10.3390/ijms22031089Test |
| DOI: |
10.3390/ijms22031089 |
| الإتاحة: |
https://doi.org/10.3390/ijms22031089Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.909EE60 |
| قاعدة البيانات: |
BASE |
