التفاصيل البيبلوغرافية
| العنوان: |
New Potential Agents for Malignant Melanoma Treatment—Most Recent Studies 2020–2022 |
| المؤلفون: |
Paweł Kozyra, Danuta Krasowska, Monika Pitucha |
| المصدر: |
International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6084 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
melanoma, targeted therapy, anticancer activity, ion channels, BRAF kinase, MAPK pathway, PI3K–AKT pathway, heterocyclic derivatives, cancer |
| جغرافية الموضوع: |
agris |
| الوصف: |
Malignant melanoma (MM) is the most lethal skin cancer. Despite a 4% reduction in mortality over the past few years, an increasing number of new diagnosed cases appear each year. Long-term therapy and the development of resistance to the drugs used drive the search for more and more new agents with anti-melanoma activity. This review focuses on the most recent synthesized anti-melanoma agents from 2020–2022. For selected agents, apart from the analysis of biological activity, the structure–activity relationship (SAR) is also discussed. To the best of our knowledge, the following literature review delivers the latest achievements in the field of new anti-melanoma agents. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| العلاقة: |
Molecular Oncology; https://dx.doi.org/10.3390/ijms23116084Test |
| DOI: |
10.3390/ijms23116084 |
| الإتاحة: |
https://doi.org/10.3390/ijms23116084Test |
| حقوق: |
https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: |
edsbas.75B22EBB |
| قاعدة البيانات: |
BASE |
