Bacillus Amyloliquefaciens-9 as an Alternative Approach to Cure Diarrhea in Saanen Kids
| العنوان: | Bacillus Amyloliquefaciens-9 as an Alternative Approach to Cure Diarrhea in Saanen Kids |
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| المؤلفون: | Huijie Xin, Wenying Zhang, Nannan Jiang, Jianhong Shu, Zhengbing Lv, Hengbo Shi |
| المصدر: | Animals Volume 11 Issue 3 Animals : an Open Access Journal from MDPI Animals, Vol 11, Iss 592, p 592 (2021) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Bacillus amyloliquefaciens, Globulin, Firmicutes, education, diarrhea, medicine.disease_cause, Article, Microbiology, lcsh:Zoology, medicine, lcsh:QL1-991, Feces, lcsh:Veterinary medicine, General Veterinary, biology, Interleukin, Pathogenic bacteria, Raw milk, biology.organism_classification, humanities, cytokines, Diarrhea, biology.protein, lcsh:SF600-1100, Animal Science and Zoology, intestinal health, medicine.symptom, microbial community, human activities |
| الوصف: | Bacillus amyloliquefaciens-9 (GBacillus-9), derived from the intestinal tract of the white-spotted bamboo shark, secretes a variety of antimicrobial compounds that inhibit the growth of pathogenic bacteria. In this study, the role of GBacillus-9 in the prevention and treatment of Saanen kids with diarrhea was assessed. Six healthy kids (HL) and six kids with diarrhea (DL) were selected. All kids were fed with 0.3% (w/v) GBacillus-9 (spray power) in raw milk for two weeks. The proportion of kids with diarrhea decreased gradually as the trial progressed, and 100% DL kids were cured at day 15. GBacillus-9 increased the serum immunoglobulin (Ig) G, interleukin (IL)-4, and IL-6 concentration (p < 0.05). The amplicon sequencing analysis of the fecal bacterial community revealed that the fecal microbiota was remarkably different between the HL and the DL groups at day 0. After two weeks of feeding with GBacillus-9, no significant difference in fecal microbiota was observed between HL and DL groups at the phylum level. GBacillus-9 restored the intestinal microbial disorder associated with serum immunoglobulin and interleukin concentration. Correlation analysis showed that GBacillus-9 altered globulin and interleukin concentration and that immunoglobulin was associated with Firmicutes. Collectively, our results revealed that GBacillus-9 improved the gut health of kids by improving microbial homeostasis |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2076-2615 |
| DOI: | 10.3390/ani11030592 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653638c9bc26316c83347f56b2e7a7b4Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....653638c9bc26316c83347f56b2e7a7b4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20762615 |
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| DOI: | 10.3390/ani11030592 |