دورية أكاديمية
Evaluating the impact on health outcomes of an event that resulted in a delay in contact tracing of COVID-19 cases in England, September 2020: an observational study.
| العنوان: | Evaluating the impact on health outcomes of an event that resulted in a delay in contact tracing of COVID-19 cases in England, September 2020: an observational study. |
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| المؤلفون: | Findlater, Lucy, Pierotti, Livia, Turner, Charlie, Wensley, Adrian, Chen, Cong, Seaman, Shaun, Samartsidis, Pantelis, Charlett, Andre, Anderson, Charlotte, Hughes, Gareth, Hickman, Matthew, Edeghere, Obaghe, Oliver, Isabel |
| بيانات النشر: | BMJ Mrc Biostatistics Unit //dx.doi.org/10.1136/bmjopen-2022-064982 BMJ Open |
| سنة النشر: | 2023 |
| المجموعة: | Apollo - University of Cambridge Repository |
| مصطلحات موضوعية: | COVID-19, EPIDEMIOLOGY, INFECTIOUS DISEASES, PUBLIC HEALTH, Humans, Contact Tracing, SARS-CoV-2, England, Outcome Assessment, Health Care |
| الوصف: | OBJECTIVE: In September 2020, 15 861 SARS-CoV-2 case records failed to upload from the Second Generation Surveillance System (SGSS) to the Contact Tracing Advisory Service (CTAS) tool, delaying the contact tracing of these cases. This study used CTAS data to determine the impact of this delay on population health outcomes: transmission events, hospitalisations and mortality. Previously, a modelling study suggested a substantial impact. DESIGN: Observational study. SETTING: England. POPULATION: Individuals testing positive for SARS-CoV-2 and their reported contacts. MAIN OUTCOME MEASURES: Secondary attack rates (SARs), hospitalisations and deaths among primary and secondary contacts were calculated, compared with all other concurrent, unaffected cases. Affected SGSS records were matched to CTAS records. Successive contacts and cases were identified and matched to hospital episode and mortality outcomes. RESULTS: Initiation of contact tracing was delayed by 3 days on average in the primary cases in the delay group (6 days) compared with the control group (3 days). This was associated with lower completion of contact tracing: 80% (95% CI: 79% to 81%) in delay group and 83% (95% CI: 83% to 84%) in control group. There was some evidence to suggest increased transmission to non-household contacts among those affected by the delay. The SAR for non-household contacts was higher among secondary contacts in the delay group than the control group (delay group: 7.9%, 95% CI: 6.5% to 9.2%; control group: 5.9%, 95% CI: 5.3% to 6.6%). There did not appear to be a significant difference between the delay and control groups in the odds of hospitalisation (crude OR: 1.1 (95% CI: 0.9 to 1.2)) or death (crude OR: 0.7 (95% CI: 0.1 to 4.0)) among secondary contacts. CONCLUSIONS: Our analysis suggests that the delay in contact tracing had a limited impact on population health outcomes; however, contact tracing was not completed for all individuals, so some transmission events might not be captured. ; LF, LP, AC, MH, and IO acknowledge ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/msword; image/tiff |
| اللغة: | English |
| العلاقة: | https://www.repository.cam.ac.uk/handle/1810/353928Test; https://doi.org/10.17863/CAM.99945Test |
| DOI: | 10.17863/CAM.99945 |
| الإتاحة: | https://doi.org/10.17863/CAM.99945Test https://www.repository.cam.ac.uk/handle/1810/353928Test |
| حقوق: | Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.325048C8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.17863/CAM.99945 |
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