دورية أكاديمية
Antiangiogenic Polyketides from Peperomia dindygulensis Miq.
العنوان: | Antiangiogenic Polyketides from Peperomia dindygulensis Miq. |
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المؤلفون: | Qi-Wei Wang, De-Hong Yu, Meng-Gan Lin, Mei Zhao, Wen-Jun Zhu, Qin Lu, Gui-Xiu Li, Chao Wang, Yi-Fang Yang, Xue-Mei Qin, Chao Fang, Hong-Zhuan Chen, Guo-Hong Yang |
المصدر: | Molecules; Volume 17; Issue 4; Pages: 4474-4483 |
بيانات النشر: | Molecular Diversity Preservation International |
سنة النشر: | 2012 |
المجموعة: | MDPI Open Access Publishing |
مصطلحات موضوعية: | Peperomia dindygulensis Miq., polyketides, antiangiogenic activity |
جغرافية الموضوع: | agris |
الوصف: | Two new polyketides: 2Z-(heptadec-12-enyl)-4-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-one (1) and 2-(heptadec-12-enyl)-5-hydroxy-5,6,7,8-tetrahydrochromen- 4-one (2), together with eleven known compounds: 4-hydroxy-2-[(3,4-methylenedioxy- phenyl)tridecanoyl] cyclohexane-1,3-dione (3), oleiferinone (4), 4-hydroxy-2-[(3,4- methylenedioxyphenyl)undecanoyl]cyclohexane-1,3-dione (5), 4-hydroxy-2-[(11-phenyl- undecanoyl)cyclohexane-1,3-dione (6), proctorione C (7), surinone C (8), 5-hydroxy- 7,8,4'-trimethoxyflavone (9), 5-hydroxy-7,8,3',4'-tetramethoxyflavone (10), 5-hydroxy- 7,3',4'-trimethoxyflavone (11), 5,8-dihydroxy-7,3',4'-trimethoxyflavone (12) and cepharanone B (13) were isolated from the whole plant of Peperomia dindygulensis Miq. Their structures were elucidated by spectroscopic methods, including 2D-NMR techniques. Compounds 2, 3, 5 and 8 inhibited human umbilical vein endothelial cell (HUVEC) proliferation and compounds 5 and 8 sharply suppressed HUVEC tube formation. |
نوع الوثيقة: | text |
وصف الملف: | application/pdf |
اللغة: | English |
العلاقة: | Natural Products Chemistry; https://dx.doi.org/10.3390/molecules17044474Test |
DOI: | 10.3390/molecules17044474 |
الإتاحة: | https://doi.org/10.3390/molecules17044474Test |
حقوق: | https://creativecommons.org/licenses/by/3.0Test/ |
رقم الانضمام: | edsbas.D852931E |
قاعدة البيانات: | BASE |
DOI: | 10.3390/molecules17044474 |
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