دورية أكاديمية

Aurantoside K, a New Antifungal Tetramic Acid Glycoside from a Fijian Marine Sponge of the Genus Melophlus

التفاصيل البيبلوغرافية
العنوان: Aurantoside K, a New Antifungal Tetramic Acid Glycoside from a Fijian Marine Sponge of the Genus Melophlus
المؤلفون: Rohitesh Kumar, Ramesh Subramani, Klaus-D. Feussner, William Aalbersberg
المصدر: Marine Drugs; Volume 10; Issue 1; Pages: 200-208
بيانات النشر: Molecular Diversity Preservation International
سنة النشر: 2012
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: marine sponges, aurantosides, antifungal, tetramic acid glycoside, Melophlus sp
جغرافية الموضوع: agris
الوصف: A new tetramic acid glycoside, aurantoside K, was isolated from a marine sponge belonging to the genus Melophlus. The structure of the compound was elucidated on the basis of spectroscopic analysis (1H NMR, 1H–1H COSY, HSQC, and HMBC, as well as high-resolution ESILCMS). Aurantoside K did not show any significant activity in antimalarial, antibacterial, or HCT-116 cytotoxicity assays, but exhibited a wide spectrum of antifungal activity against wild type Candida albicans, amphotericin-resistant C. albicans, Cryptococcus neoformans, Aspergillus niger, Penicillium sp., Rhizopus sporangia and Sordaria sp.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
العلاقة: https://dx.doi.org/10.3390/md10010200Test
DOI: 10.3390/md10010200
الإتاحة: https://doi.org/10.3390/md10010200Test
حقوق: https://creativecommons.org/licenses/by/3.0Test/
رقم الانضمام: edsbas.EA538E4A
قاعدة البيانات: BASE