Short-term outcomes of type 2 diabetes mellitus patients treated with canagliflozin in real-world setting
| العنوان: | Short-term outcomes of type 2 diabetes mellitus patients treated with canagliflozin in real-world setting |
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| المؤلفون: | Manash P Baruah, Sanjay Kalra |
| المصدر: | Indian Journal of Endocrinology and Metabolism Indian Journal of Endocrinology and Metabolism, Vol 20, Iss 1, Pp 137-141 (2016) |
| بيانات النشر: | Medknow Publications & Media Pvt Ltd, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, type 2 diabetes mellitus, Endocrinology, Diabetes and Metabolism, Antihyperglycemic Agents, India, 030209 endocrinology & metabolism, Type 2 diabetes, Brief Communication, lcsh:Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Internal medicine, Medicine, 030212 general & internal medicine, lcsh:RC799-869, Canagliflozin, Glycemic, lcsh:RC648-665, business.industry, sodium glucose co-transporter 2 inhibitors, Type 2 Diabetes Mellitus, Retrospective cohort study, Mean age, medicine.disease, Surgery, lcsh:Diseases of the digestive system. Gastroenterology, business, medicine.drug |
| الوصف: | Objective: This study is aimed to evaluate the characteristics, treatment, and outcomes of patients treated with canagliflozin in the real-world setting within the first 4 months of the product's availability in India. Patients and Methods: It is a retrospective study with data collected from Indian clinical database. Patients aged 18 and above who were prescribed canagliflozin were included in this study. All the patients were on other antihyperglycemic agents (AHAs) before the initiation of canagliflozin. Results: Overall, nine patients were included in the study, and data for these patients with mean duration of follow-up of 16 weeks was analyzed. Mean age was 47.9 years and mean duration of type 2 diabetes was 6.7 years. Among patients with available laboratory data at baseline and follow-up, mean glycosylated hemoglobin A1c (HbA1c) decreased from 9.0% at baseline to 6.8% at follow-up (P < 0.005); mean weight reduced from 69.9 kg at baseline to 67.9 kg at follow-up. When compared to baseline, the usage and or dose of other AHAs were reduced during follow-up. Conclusion: Canagliflozin after it became available in India, improved all glycemic parameters and also reduced the weight of the type two diabetic patients who were poorly controlled by multiple AHAs. |
| اللغة: | English |
| تدمد: | 2230-9500 2230-8210 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1923e83246a96e8fa9fb6bac53394cTest http://europepmc.org/articles/PMC4743376Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7f1923e83246a96e8fa9fb6bac53394c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22309500 22308210 |
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