التفاصيل البيبلوغرافية
| العنوان: |
Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study. |
| المؤلفون: |
Noronha, Vanita, Chougule, Anuradha, Chandrani, Pratik, Kaushal, Rajiv Kumar, Patil, Vijay Maruti, Menon, Nandini, Kapoor, Akhil, Chopade, Sunil, Singh, Ajaykumar, Shetty, Omshree, Dutt, Amit, Banavali, Shripad, Prabhash, Kumar |
| المصدر: |
Acta Oncologica; Sep2022, Vol. 61 Issue 9, p1143-1147, 5p, 1 Chart, 1 Graph |
| مصطلحات موضوعية: |
LUNG cancer prognosis, LUNG cancer, GENETIC mutation, SCIENTIFIC observation, SPECIALTY hospitals, CONFIDENCE intervals, EPIDERMAL growth factor receptors, ONCOGENES, CANCER chemotherapy, MULTIVARIATE analysis, RETROSPECTIVE studies, ACQUISITION of data, METASTASIS, ANAPLASTIC lymphoma kinase, GENE expression, CANCER treatment, PROTEIN-tyrosine kinase inhibitors, MOLECULAR biology, TREATMENT effectiveness, MEDICAL records, CASE studies, DESCRIPTIVE statistics, PROGRESSION-free survival, DATA analysis software, DRUG side effects, LONGITUDINAL method, DRUG toxicity, DRUG resistance in cancer cells, PROPORTIONAL hazards models |
| مصطلحات جغرافية: |
INDIA |
| مستخلص: |
The article focuses on lung cancer therapy which began with the discovery of actionable genomic alterations. Topics include examines the two most well described molecular alterations are the epidermal growth factor receptor mutation and ALK fusion as initially thought that these oncogenic drivers are mutually exclusive, i.e. only a single driver per tumor. |
| قاعدة البيانات: |
Complementary Index |
