A Radiological Scoring System for Differentiation between Enchondroma and Chondrosarcoma
| العنوان: | A Radiological Scoring System for Differentiation between Enchondroma and Chondrosarcoma |
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| المؤلفون: | Yohei Asano, Norio Yamamoto, Shinji Miwa, Takayuki Nojima, Akihiko Takeuchi, Hiroyuki Tsuchiya, Kaoru Tada, Katsuhiro Hayashi, Kentaro Igarashi, Yoshihiro Araki, Miho Okuda, Hiroko Ikeda, Hirotaka Yonezawa, Shiro Saito, Sei Morinaga, Junichi Taki |
| المصدر: | Cancers, Vol 13, Iss 3558, p 3558 (2021) Cancers Volume 13 Issue 14 |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cancer Research, medicine.medical_specialty, Scoring system, Periosteal reaction, Article, enchondroma, 030218 nuclear medicine & medical imaging, X-ray, Lesion, 03 medical and health sciences, 0302 clinical medicine, radiological scoring system, Enchondroma, thallium scan, Medicine, Medical diagnosis, RC254-282, chondrosarcoma, business.industry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, differentiation, medicine.disease, atypical cartilaginous tumors, Oncology, 030220 oncology & carcinogenesis, Radiological weapon, Cohort, bone scan, Radiology, Chondrosarcoma, medicine.symptom, business, MRI, CT |
| الوصف: | Background: It is challenging to differentiate between enchondromas and atypical cartilaginous tumors (ACTs)/chondrosarcomas. In this study, correlations between radiological findings and final diagnosis were investigated in patients with central cartilaginous tumors. Methods: To evaluate the diagnostic usefulness of radiological findings, correlations between various radiological findings and final diagnoses were investigated in a cohort of 81 patients. Furthermore, a new radiological scoring system was developed by combining radiological findings. Results: Periosteal reaction on X-ray (p = 0.025), endosteal scalloping (p = 0.010) and cortical defect (p = 0.002) on CT, extraskeletal mass (p < 0.001), multilobular lesion (p < 0.001), abnormal signal in adjacent tissue (p = 0.004) on MRI, and increased uptake in bone scan (p = 0.002) and thallium scan (p = 0.027) was significantly correlated with final diagnoses. Based on the correlations between each radiological finding and postoperative histological diagnosis, a radiological scoring system combining these findings was developed. In another cohort of 17 patients, the sensitivity, specificity, and accuracy of the radiological score rates for differentiation between enchondromas and ACTs/chondrosarcomas were 88%, 89%, and 88%, respectively (p = 0.003). Conclusion: Radiological assessment with combined radiological findings is recommended to differentiate between enchondromas and ACT/chondrosarcomas. |
| وصف الملف: | application/pdf |
| تدمد: | 2072-6694 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dab56be3db241bc8ac886e5216200f1Test https://doi.org/10.3390/cancers13143558Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6dab56be3db241bc8ac886e5216200f1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726694 |
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