Exploring the Genetic Background of the Differences in Nest-Building Behavior in European Rabbit
| العنوان: | Exploring the Genetic Background of the Differences in Nest-Building Behavior in European Rabbit |
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| المؤلفون: | Tamás Molnár, Attila Zsolnai, Ildikó Benedek, Vilmos Altbӓcker |
| المصدر: | Animals, Vol 10, Iss 1579, p 1579 (2020) Animals Volume 10 Issue 9 Animals : an Open Access Journal from MDPI |
| بيانات النشر: | MDPI AG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Single-nucleotide polymorphism, heritability, Article, progesterone receptor, 03 medical and health sciences, Progesterone receptor, Genotype, lcsh:Zoology, biology.domesticated_animal, SNP, lcsh:QL1-991, Gene, 030304 developmental biology, Genetics, 0303 health sciences, lcsh:Veterinary medicine, General Veterinary, biology, Point mutation, 0402 animal and dairy science, Promoter, 04 agricultural and veterinary sciences, 040201 dairy & animal science, hay carrying, lcsh:SF600-1100, Animal Science and Zoology, European rabbit, maternal behavior |
| الوصف: | Once a day, nursing and absentee mothering make the wild rabbit (Oryctolagus cuniculus) an ideal model animal for measuring differences in maternal behavior. Behavioral events and their hormonal regulation leading to parturition are well documented however, the genetic background behind individual differences in this complex process is unknown. Decreased progesterone hormone level and the reduction of progesterone receptor activity are crucial to initiating the collection of nest material. The progesterone receptor gene is a likely candidate affecting nest-building behavior. In addition to several known point mutations in the progesterone receptor gene of the European wild rabbit, we have found a new mutation in the promoter region of the gene at 2682 T > C. Although this new single nucleotide polymorphism (SNP) was not involved in the formation of the nest-building behavior, an SNP (2464G > A) already described in the promoter region showed an association with individual differences in the initiation of hay carrying. The distribution of this SNP delivered an opposite result compared to domestic rabbits. Genotype (GG) with high uterine capacity was most frequent the hereditary value of the trait was h2 = 0.10. Thus, progesterone receptor gene polymorphism may manifest in individual differences affecting breeding success in this species. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2076-2615 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b23aa78992e6f28c6bb95cf82e3b46Test https://www.mdpi.com/2076-2615/10/9/1579Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....20b23aa78992e6f28c6bb95cf82e3b46 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20762615 |
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