دورية أكاديمية
Chitosan–Hydroxycinnamic Acids Conjugates: Emerging Biomaterials with Rising Applications in Biomedicine
| العنوان: | Chitosan–Hydroxycinnamic Acids Conjugates: Emerging Biomaterials with Rising Applications in Biomedicine |
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| المؤلفون: | Doddy Denise Ojeda-Hernández, Alejandro A. Canales-Aguirre, Jordi A. Matias-Guiu, Jorge Matias-Guiu, Ulises Gómez-Pinedo, Juan Carlos Mateos-Díaz |
| المصدر: | International Journal of Molecular Sciences, Vol 23, Iss 20, p 12473 (2022) |
| بيانات النشر: | MDPI AG, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Biology (General) LCC:Chemistry |
| مصطلحات موضوعية: | chitosan, hydroxycinnamic acids, biomaterials, biomedical applications, conjugates, chitosan derivatives, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | Over the past thirty years, research has shown the huge potential of chitosan in biomedical applications such as drug delivery, tissue engineering and regeneration, cancer therapy, and antimicrobial treatments, among others. One of the major advantages of this interesting polysaccharide is its modifiability, which facilitates its use in tailor-made applications. In this way, the molecular structure of chitosan has been conjugated with multiple molecules to modify its mechanical, biological, or chemical properties. Here, we review the conjugation of chitosan with some bioactive molecules: hydroxycinnamic acids (HCAs); since these derivatives have been probed to enhance some of the biological effects of chitosan and to fine-tune its characteristics for its application in the biomedical field. First, the main characteristics of chitosan and HCAs are presented; then, the currently employed conjugation strategies between chitosan and HCAs are described; and, finally, the studied biomedical applications of these derivatives are discussed to present their limitations and advantages, which could lead to proximal therapeutic uses. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| العلاقة: | https://www.mdpi.com/1422-0067/23/20/12473Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test |
| DOI: | 10.3390/ijms232012473 |
| الوصول الحر: | https://doaj.org/article/38f3b8a697264787afbcf3f18ba247ceTest |
| رقم الانضمام: | edsdoj.38f3b8a697264787afbcf3f18ba247ce |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms232012473 |