دورية أكاديمية

Bovine Viral Diarrhea Virus Antibody Level Variation in Newborn Calves after Vaccination of Late-Gestational Cows

التفاصيل البيبلوغرافية
العنوان: Bovine Viral Diarrhea Virus Antibody Level Variation in Newborn Calves after Vaccination of Late-Gestational Cows
المؤلفون: Ui-Hyung Kim, Sung-Sik Kang, Sun-Sik Jang, Sung Woo Kim, Ki-Yong Chung, Dong-Hun Kang, Bo-Hye Park, Seungmin Ha
المصدر: Veterinary Sciences, Vol 10, Iss 562, p 562 (2023)
بيانات النشر: MDPI AG
سنة النشر: 2023
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: antibody, BVDV, calf, cow, vaccine, Veterinary medicine, SF600-1100
الوصف: This study was conducted to confirm variation in bovine viral diarrhea virus (BVDV) antibody levels transferred to calves from their mother’s colostrum after vaccination of late-gestational cows. Blood samples were drawn from 60 pregnant cows that had been vaccinated more than one year and less than two years previously. The samples were collected six weeks prior to the expected date of delivery. After sample collection, the cows were divided into two groups of 30. One group received 2 mL of BVDV vaccine, and a control group received 2 mL of phosphate-buffered saline (PBS). Blood was collected from the cows three weeks post-administration. Additional blood samples were taken from calves at 1, 4, 8, 12, 16, and 20 weeks after birth. The serum was separated from the collected blood, and BVDV antibody changes were confirmed by enzyme-linked immunosorbent assays. BVDV antibody levels were higher from 8 to 20 weeks of age in calves born to late-gestational BVDV-vaccinated cows than in calves born to control cows ( p < 0.0083). Further analysis confirmed a slow decline in BVDV maternal antibodies in calves born to pregnant cows that produced high levels of BVDV antibodies following pre-calving BVDV vaccination. These results suggest that BVDV vaccination of cattle in late pregnancy may help to extend the duration of protection against BVDV infection in newborn calves.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2306-7381
العلاقة: https://www.mdpi.com/2306-7381/10/9/562Test; https://doaj.org/toc/2306-7381Test; https://doaj.org/article/5d29b0af88c1432aa8500d69ba56f808Test
DOI: 10.3390/vetsci10090562
الإتاحة: https://doi.org/10.3390/vetsci10090562Test
https://doaj.org/article/5d29b0af88c1432aa8500d69ba56f808Test
رقم الانضمام: edsbas.688F262A
قاعدة البيانات: BASE
الوصف
تدمد:23067381
DOI:10.3390/vetsci10090562