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المؤلفون: Fabio Arturo Iannotti, Fabiana Piscitelli, Pietro Amodeo, Rosa Maria Vitale, Vincenzo Di Marzo, Ranjev Savopoulos, Luigia Cristino, Aniello Schiano Moriello, Royston A. Gray, Luciano De Petrocellis, Lea Tunisi
المصدر: Biomolecules, Vol 11, Iss 1134, p 1134 (2021)
Biomolecules
Volume 11
Issue 8
Biomolecules 11 (2021). doi:10.3390/biom11081134
info:cnr-pdr/source/autori:Vitale R.M.; Iannotti F.A.; Moriello A.S.; Tunisi L.; Piscitelli F.; Savopoulos R.; Cristino L.; De Petrocellis L.; Amodeo P.; Gray R.; Di Marzo V./titolo:Identification and characterization of cannabidiol as an ox1r antagonist by computational and in vitro functional validation/doi:10.3390%2Fbiom11081134/rivista:Biomolecules/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Gene Expression, Pharmacology, Biochemistry, Radioligand Assay, cannabidiol, 0302 clinical medicine, Transgenes, Receptor, media_common, Chemistry, calcium mobilization assay, Ligand (biochemistry), calcium influx assay, Orexin receptor, QR1-502, Molecular Imaging, Molecular Docking Simulation, calcium imaging, Anticonvulsants, Orexin Receptor Antagonists, Protein Binding, medicine.drug, Drug, orexin receptors, OX1R, media_common.quotation_subject, CHO Cells, Microbiology, Article, 03 medical and health sciences, Cricetulus, medicine, Animals, Humans, Protein Interaction Domains and Motifs, Molecular Biology, Orexins, Binding Sites, Antagonist, antagonist, molecular docking, In vitro, molecular dynamics, Orexin, Kinetics, 030104 developmental biology, Anti-Anxiety Agents, Calcium, Protein Conformation, beta-Strand, Cannabidiol, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774e5847c77075e8bf23ab08f2e5ffadTest
https://www.mdpi.com/2218-273X/11/8/1134Test -
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المؤلفون: Rubén Nogueiras, Amparo Romero-Picó, Carlos Dieguez, Laura Liñares-Pose, Ánxela Estévez-Salguero, Patricia Seoane-Collazo, Eva Rial-Pensado, Johan Fernø, Miguel López
المساهمون: Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Fisioloxía
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 1515, p 1515 (2021)
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
International Journal of Molecular Sciences
Volume 22
Issue 4
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instnameمصطلحات موضوعية: 0301 basic medicine, Male, AMPK, Lateral hypothalamus, Dynorphin, White adipose tissue, AMP-Activated Protein Kinases, Nicotine, Rats, Sprague-Dawley, lcsh:Chemistry, Mice, 0302 clinical medicine, Brown adipose tissue, lcsh:QH301-705.5, Spectroscopy, Chemistry, General Medicine, lateral hypothalamus, 3. Good health, Computer Science Applications, medicine.anatomical_structure, mTOR, medicine.drug, Signal Transduction, medicine.medical_specialty, P70-S6 Kinase 1, κ-opioid receptor, Dynorphins, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Kappa opioid receptor, Internal medicine, medicine, Animals, Physical and Theoretical Chemistry, kappa opioid receptor, Molecular Biology, Receptors, Opioid, kappa, Organic Chemistry, Body Weight, Orexin, Rats, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, Hypothalamic Area, Lateral, Energy Metabolism, 030217 neurology & neurosurgery, nicotine
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b329900de458a2f61508eea72bf10beTest
https://www.mdpi.com/1422-0067/22/4/1515Test -
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المؤلفون: Eugenie Nepovimova, Eva Mezeiova, Rafael Dolezal, Vendula Hepnarova, Jana Janockova, Michaela Melikova, Marketa Benkova, Kamil Kuca, Tereza Kobrlova, Jan Korabecny, Ondrej Soukup, Avi Ring, Jan Konecny
المصدر: Molecules, Vol 23, Iss 11, p 2926 (2018)
Molecules
Volume 23
Issue 11مصطلحات موضوعية: 0301 basic medicine, Agonist, Intrinsic activity, Cataplexy, structure-based virtual screening, medicine.drug_class, Pharmaceutical Science, narcolepsy, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, Orexin-A, 0302 clinical medicine, lcsh:Organic chemistry, Drug Discovery, mental disorders, medicine, orexin A, Physical and Theoretical Chemistry, orexin receptor modulators, Chemistry, Organic Chemistry, Suvorexant, digestive, oral, and skin physiology, suvorexant, medicine.disease, Orexin receptor, Orexin, 030104 developmental biology, nervous system, Chemistry (miscellaneous), Molecular Medicine, medicine.symptom, Neuroscience, 030217 neurology & neurosurgery, psychological phenomena and processes, Narcolepsy
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33726147b2063913e801058e0ca26493Test
https://www.mdpi.com/1420-3049/23/11/2926Test -
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المؤلفون: Haidong Wei, Jianhong Li, Xiang Li, Chun Li, Jun Bao, Shuang Li, Runxiang Zhang, Hongwei Xin, Yanju Bi
المصدر: Animals, Vol 9, Iss 10, p 804 (2019)
Animals : an Open Access Journal from MDPI
Animals
Volume 9
Issue 10مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Inflammation, Article, stress, 03 medical and health sciences, chemistry.chemical_compound, Corticosterone, Internal medicine, Heat shock protein, lcsh:Zoology, medicine, lcsh:QL1-991, lcsh:Veterinary medicine, General Veterinary, biology, laying hens, 0402 animal and dairy science, 04 agricultural and veterinary sciences, 040201 dairy & animal science, Hsp90, Hsp70, Orexin, Nitric oxide synthase, keel fracture, 030104 developmental biology, Endocrinology, orexin, chemistry, inflammation, biology.protein, lcsh:SF600-1100, Animal Science and Zoology, Tumor necrosis factor alpha, medicine.symptom
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e610523fa27389902c89f7c1e329081Test
https://doi.org/10.3390/ani9100804Test -
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المؤلفون: Domenico Tafuri, Giuseppe Cibelli, Marcellino Monda, Giovanni Messina, Antonietta Messina, Rita Polito, Anna Valenzano, Angelo Campanozzi, Francesco Sessa, Nicola Tartaglia, Vincenzo Monda, Antonio Ambrosi
المصدر: Journal of Clinical Medicine
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Orexin-A, Adipose tissue, Adipokine, 030209 endocrinology & metabolism, Inflammation, Review, Type 2 diabetes, 03 medical and health sciences, 0302 clinical medicine, Weight loss, medicine, Obesity, Bariatric surgery, Adiponectin, business.industry, digestive, oral, and skin physiology, General Medicine, medicine.disease, Surgery, obesity, adipose tissue, adiponectin, central nervous system, bariatric surgery, 030104 developmental biology, Central nervous system, medicine.symptom, business, hormones, hormone substitutes, and hormone antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291a805701ad331ad4f8bcd88864f610Test
https://doi.org/10.3390/jcm9103327Test -
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المصدر: Pharmaceuticals, Vol 10, Iss 4, p 79 (2017)
Pharmaceuticalsمصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Lateral hypothalamus, medicine.drug_class, CB1 cannabinoid receptor, medicine.medical_treatment, feeding behavior, lcsh:Medicine, lcsh:RS1-441, Pharmaceutical Science, Review, Biology, OX1 orexin receptor, lcsh:Pharmacy and materia medica, 03 medical and health sciences, Feeding behavior, Hetero-dimerization, Homo-dimerization, Opioid receptor, Orexin/hypocretin, OX2 orexin receptor, Sleep disorder, Status epilepticus, Molecular Medicine, 3003, 0302 clinical medicine, Internal medicine, mental disorders, Drug Discovery, medicine, Receptor, sleep disorder, G protein-coupled receptor, status epilepticus, lcsh:R, digestive, oral, and skin physiology, opioid receptor, medicine.disease, Orexin receptor, 3. Good health, Orexin, orexin/hypocretin, hetero-dimerization, 030104 developmental biology, Endocrinology, nervous system, Cannabinoid, homo-dimerization, hormones, hormone substitutes, and hormone antagonists, psychological phenomena and processes, 030217 neurology & neurosurgery, Narcolepsy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6c8c3a9ad4071cf1f2967b7a608658Test
https://doi.org/10.3390/ph10040079Test -
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المؤلفون: Stefano Bastianini, Alessandro Silvani
المساهمون: Bastianini, S, Silvani, A
المصدر: Clinical and Translational Neuroscience. 2:2514183X1878932
مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, Cataplexy, Dementia with Lewy bodies, business.industry, Disease, Orexins, hypocretins, narcolepsy, cataplexy, sympathetic, parasympathetic, Alzheimer’s disease, Parkinson’s disease, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Atrophy, nervous system, Basic research, medicine, medicine.symptom, business, Neuroscience, 030217 neurology & neurosurgery, Narcolepsy, Hypocretin orexin
وصف الملف: ELETTRONICO
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bbefb20a27c4f4e5b917f708bd1025Test
https://doi.org/10.1177/2514183x18789327Test -
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المؤلفون: Chun Hua Ren, Dong Sheng Tang, Yi Ming Cai, Chao Qun Hu, Shuang Chen, Ai Fen Yan, Ting Chen, Fang Liu
المصدر: International Journal of Molecular Sciences, Vol 17, Iss 6, p 783 (2016)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 6; Pages: 783مصطلحات موضوعية: 0301 basic medicine, lcsh:Chemistry, Eating, Neuropeptide Y, goldfish, lcsh:QH301-705.5, Spectroscopy, media_common, biology, Leptin, digestive, oral, and skin physiology, Brain, General Medicine, feeding control, Neuropeptide Y receptor, Recombinant Proteins, Computer Science Applications, Hypothalamus, Receptors, Leptin, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Fish Proteins, medicine.medical_specialty, methylotrophic yeast, media_common.quotation_subject, leptin, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, appetite regulators, Proopiomelanocortin, Internal medicine, Orexigenic, medicine, Animals, Physical and Theoretical Chemistry, Molecular Biology, Leptin receptor, Organic Chemistry, Appetite, Feeding Behavior, Orexin, gene regulation, 030104 developmental biology, Endocrinology, Gene Expression Regulation, lcsh:Biology (General), lcsh:QD1-999, nervous system, biology.protein, sense organs
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbd5c6475cca494cfc88fd167ab3e37Test
https://doi.org/10.3390/ijms17060783Test
