دورية أكاديمية
Interhemispheric Pediatric Meningioma, YAP1 Fusion-Positive
| العنوان: | Interhemispheric Pediatric Meningioma, YAP1 Fusion-Positive |
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| المؤلفون: | Esposito S., Marucci G., Antonelli M., Miele E., Modena P., Giagnacovo M., Massimino M., Biassoni V., Taddei M., Schiariti M. P., Doniselli F. M., Moscatelli M., Chiapparini L., Pollo B. |
| المساهمون: | S. Esposito, G. Marucci, M. Antonelli, E. Miele, P. Modena, M. Giagnacovo, M. Massimino, V. Biassoni, M. Taddei, M.P. Schiariti, F.M. Doniselli, M. Moscatelli, L. Chiapparini, B. Pollo |
| بيانات النشر: | MDPI |
| سنة النشر: | 2022 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | interhemispheric meningioma, methylation profile, pediatric meningioma, YAP1-fusion, Settore MED/37 - Neuroradiologia, Settore MED/08 - Anatomia Patologica, Settore MED/06 - Oncologia Medica |
| الوصف: | Meningiomas are uncommon in children and usually arise in the context of tumor-predisposing syndromes. Recently, YAP1-fusions have been identified for the first time as potential NF2-independent oncogenic drivers in the development of meningiomas in pediatric patients. We report a case of a YAP1-fusion-positive atypical meningioma in a young child and compare it with the previous ones reported. Extending the clinico-pathological features of YAP1-fused meningiomas, we suggest additional clues for diagnosis and emphasize the urgent need for an integrated multilayered diagnostic approach, combining data from histological and molecular analyses, neuroradiology, and clinical findings. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36292056; info:eu-repo/semantics/altIdentifier/wos/WOS:000872677600001; volume:12; issue:10; firstpage:1; lastpage:7; numberofpages:7; journal:DIAGNOSTICS; https://hdl.handle.net/2434/957259Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85140655808 |
| DOI: | 10.3390/diagnostics12102367 |
| الإتاحة: | https://doi.org/10.3390/diagnostics12102367Test https://hdl.handle.net/2434/957259Test |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.60A5DBF2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/diagnostics12102367 |
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