Bilateral Diffuse Nodular Pulmonary Ossification Mimicking Metastatic Disease in a Patient with Fibrolamellar Hepatocellular Carcinoma
| العنوان: | Bilateral Diffuse Nodular Pulmonary Ossification Mimicking Metastatic Disease in a Patient with Fibrolamellar Hepatocellular Carcinoma |
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| المؤلفون: | Cara E. Morin, Wayne L. Furman, Teresa Santiago, Max R Langham, Pattamon Sutthatarn, Jessica Gartrell, Andrew J. Murphy |
| المصدر: | Children Children, Vol 8, Iss 226, p 226 (2021) |
| بيانات النشر: | MDPI, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Chemotherapy, Pathology, medicine.medical_specialty, business.industry, medicine.medical_treatment, lcsh:RJ1-570, Histology, lcsh:Pediatrics, Case Report, Disease, Pulmonary ossification, pulmonary calcification, medicine.disease, diffuse nodular pulmonary ossification, Fibrolamellar hepatocellular carcinoma, Pediatrics, Perinatology and Child Health, Parenchyma, medicine, fibrolamellar hepatocellular carcinoma, Hepatectomy, business, Rare disease |
| الوصف: | Pulmonary ossification (PO) is a rare finding, characterized by mature bone formation in the lung parenchyma. We report a 20-year-old female patient diagnosed with fibrolamellar hepatocellular carcinoma (FL-HCC) and bilateral diffuse nodular PO. The patient presented with a unifocal left liver mass and multiple bilateral pulmonary lesions, which were treated as metastatic disease. The patient received neoadjuvant chemotherapy, followed by left hepatectomy, and bilateral staged thoracotomies for clearance of the pulmonary disease. The histology of the pulmonary nodules demonstrated nodular type PO. We present the history, the course of treatment, imaging, and histologic findings of this rare disease process that could mimic metastatic pulmonary disease. |
| اللغة: | English |
| تدمد: | 2227-9067 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4ae689694d25a19f3fb5bd8124f656Test http://europepmc.org/articles/PMC8002229Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....7d4ae689694d25a19f3fb5bd8124f656 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22279067 |
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