Following Pediatric and Adult IBD Patients through the COVID-19 Pandemic: Changes in Psychosocial Burden and Perception of Infection Risk and Harm over Time
| العنوان: | Following Pediatric and Adult IBD Patients through the COVID-19 Pandemic: Changes in Psychosocial Burden and Perception of Infection Risk and Harm over Time |
|---|---|
| المؤلفون: | Tobias Schwerd, Andreas Wieser, Leandra Koletzko, Raquel Rubio-Acero, Marie Standl, Sibylle Koletzko, Lukas Neuhaus, Thu Giang Le Thi, Elisabeth Klucker, Renee Stark, Simone Breiteneicher, Helga Török |
| المصدر: | Journal of Clinical Medicine J. Clin. Med. 10:4124 (2021) Volume 10 Issue 18 Journal of Clinical Medicine, Vol 10, Iss 4124, p 4124 (2021) |
| بيانات النشر: | MDPI, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Crohn’s disease, Crohn's disease, Sleep disorder, business.industry, SARS-CoV-2, Covid-19, Crohn’s Disease, Psychosocial Stress, Sars-cov-2, Ulcerative Colitis, Weight change, COVID-19, General Medicine, medicine.disease, Logistic regression, Article, Risk perception, Quality of life, medicine, Medicine, psychosocial stress, medicine.symptom, business, Weight gain, Psychosocial, Demography, ulcerative colitis |
| الوصف: | Background: COVID-19-associated restrictions impact societies. We investigated the impact in a large cohort of inflammatory bowel disease (IBD) patients. Methods: Pediatric (pIBD) and adult patients and pIBD parents completed validated questionnaires for self-perceived stress (Perceived Stress Questionnaire, PSQ) and quality of life from July to October 2020 (1st survey) and March to April 2021 (2nd survey). Analyses were stratified by age groups (6–20, > 20–40, > 40–60, > 60 years). Perceived risk of infection and harm from COVID-19 were rated on a 1–7 scale. An index for severe outcome (SIRSCO) was calculated. Multivariable logistic regression analysis was performed. Results: Of 820 invited patients, 504 (62%, 6–85 years) patients and 86 pIBD parents completed the 1st, thereof 403 (80.4%) the 2nd survey. COVID-19 restrictions resulted in cancelled doctoral appointments (26.7%), decreased physical activity, increased food intake, unintended weight gain and sleep disturbance. PSQ increased with disease activity. Elderly males rated lower compared to females or younger adults. PSQ in pIBD mothers were comparable to moderate/severe IBD adults. Infection risk and harm were perceived high in 36% and 75.4%. Multivariable logistic models revealed associations of higher perceived risk with > 3 household members, job conditions and female gender, and of perceived harm with higher SIRSCO, unintended weight change, but not with gender or age. Cancelled clinic-visits were associated with both. SARS-CoV-2 antibodies prior 2nd infection wave were positive in 2/472 (0.4%). Conclusions: IBD patients report a high degree of stress and self-perceived risk of complications from COVID-19 with major differences related to gender and age. Low seroprevalence may indicate altered immune response. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2077-0383 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900a083d58d6d4a8f30e8f300f85b6b4Test http://europepmc.org/articles/PMC8464949Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....900a083d58d6d4a8f30e8f300f85b6b4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20770383 |
|---|