نتائج البحث - "Physiologically based pharmacokinetic modelling"

1

دورية أكاديمية

Human Biomonitoring Guidance Values (HBM-GVs) for Bisphenol S and Assessment of the Risk Due to the Exposure to Bisphenols A and S, in Europe

المؤلفون: Meslin, Matthieu, Beausoleil, Claire, Zeman, Florence, Antignac, Jean-Philippe, Kolossa-Gehring, Marike, Rousselle, Christophe, Apel, Petra

المساهمون: Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Institut National de l'Environnement Industriel et des Risques (INERIS), Laboratoire d'étude des Résidus et Contaminants dans les Aliments (LABERCA), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), German Federal Environmental Agency / Umweltbundesamt (UBA), European Project: 733032,H2020,HBM4EU(2017)

المصدر: ISSN: 2305-6304 ; Toxics ; https://anses.hal.science/anses-03661044Test ; Toxics, 2022, 10 (5), pp.228. ⟨10.3390/toxics10050228⟩ ; https://wwwTest.mdpi.com/2305-6304/10/5/228.

مصطلحات موضوعية: human biomonitoring (HBM), HBM4EU, internal exposure, biomarkers, endocrine disruptors, bisphenol A (BPA), bisphenol S (BPS), bisphenols, human biomonitoring guidance value (HBM-GV), physiologically based pharmacokinetic modelling (PBPK), risk assessment, [SDV.TOX]Life Sciences [q-bio]/Toxicology, [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35622642; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; anses-03661044; https://anses.hal.science/anses-03661044Test; https://anses.hal.science/anses-03661044/documentTest; https://anses.hal.science/anses-03661044/file/Meslin_Toxics_2022.pdfTest; PUBMED: 35622642; WOS: 000803380300001

الإتاحة: https://doi.org/10.3390/toxics10050228Test
https://anses.hal.science/anses-03661044Test
https://anses.hal.science/anses-03661044/documentTest
https://anses.hal.science/anses-03661044/file/Meslin_Toxics_2022.pdfTest

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2

دورية أكاديمية

The Impact of Low Cardiac Output on Propofol Pharmacokinetics across Age Groups-An Investigation Using Physiologically Based Pharmacokinetic Modelling

المؤلفون: Allegaert, Karel, Abbasi, Mohammad Yaseen, Michelet, Robin, Olafuyi, Olusola

المساهمون: Medicine, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Propofol, Low cardiac output, Pharmacokinetics, Neonate, Developmental pharmacology, Asphyxia, Hypothermia, Pediatrics

وصف الملف: application/pdf

العلاقة: Pharmaceutics; Allegaert K, Abbasi MY, Michelet R, Olafuyi O. The Impact of Low Cardiac Output on Propofol Pharmacokinetics across Age Groups-An Investigation Using Physiologically Based Pharmacokinetic Modelling. Pharmaceutics. 2022;14(9):1957. Published 2022 Sep 16. doi:10.3390/pharmaceutics14091957; https://hdl.handle.net/1805/35113Test

الإتاحة: https://doi.org/10.3390/pharmaceutics14091957Test
https://hdl.handle.net/1805/35113Test

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3

QSAR-Based Virtual Screening of Natural Products Database for Identification of Potent Antimalarial Hits

المؤلفون: Aline Rimoldi, José T. Moreira-Filho, Joyce V. V. B. Borba, Letícia Tiburcio Ferreira, Fabio T. M. Costa, Carolina Horta Andrade

المصدر: Biomolecules
Volume 11
Issue 3
Biomolecules, Vol 11, Iss 459, p 459 (2021)

مصطلحات موضوعية: Quantitative structure–activity relationship, Physiologically based pharmacokinetic modelling, natural products, In silico, Plasmodium falciparum, lcsh:QR1-502, Quantitative Structure-Activity Relationship, Context (language use), Computational biology, Biology, 01 natural sciences, Biochemistry, lcsh:Microbiology, Article, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, experimental validation, medicine, Artemisinin, Molecular Biology, 030304 developmental biology, ADME, 0303 health sciences, Virtual screening, Biological Products, Natural product, Quinine, QSAR, virtual screening, Artemisinins, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e563a55c9835c5245f73d20d9fabebeTest
http://europepmc.org/articles/PMC8003391Test

4

Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infrared Dye: A Physiologically Based Pharmacokinetic Modelling Approach

المؤلفون: Xiaoqiang Xiang, Haisheng He, Ning Ding, Wei Wu, Lei Li, Yi Lu, Sifang Jiang, Jianping Qi, Hai-Shu Lin

المصدر: Molecules
Molecules, Vol 26, Iss 1271, p 1271 (2021)
Molecules; Volume 26; Issue 5; Pages: 1271

مصطلحات موضوعية: Biodistribution, Physiologically based pharmacokinetic modelling, Polymers, Phagocytosis, Polyesters, physiologically based pharmacokinetic model, Pharmaceutical Science, Nanoparticle, 02 engineering and technology, 030226 pharmacology & pharmacy, Article, Analytical Chemistry, Polyethylene Glycols, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Drug Delivery Systems, lcsh:Organic chemistry, In vivo, Drug Discovery, Animals, Humans, Computer Simulation, Pharmacokinetics, Physical and Theoretical Chemistry, Coloring Agents, biodistribution, Chemistry, Organic Chemistry, phagocytosis, 021001 nanoscience & nanotechnology, methoxy poly (ethylene glycol)-poly (ε-caprolactone), nanoparticles, Chemistry (miscellaneous), Permeability (electromagnetism), Polycaprolactone, Biophysics, Molecular Medicine, Nanoparticles, 0210 nano-technology, Ethylene glycol

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200b6b2fad1de144c05db876c656a8d2Test
http://europepmc.org/articles/PMC7956253Test

5

Evaluation of Pharmacokinetic Drug–Drug Interactions: A Review of the Mechanisms, In Vitro and In Silico Approaches

المؤلفون: Zeneng Cheng, Feifan Xie, Yaru Peng

المصدر: Metabolites
Metabolites, Vol 11, Iss 75, p 75 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a34fc932d7cd4bcd5f0c31bd03c238dTest
http://europepmc.org/articles/PMC7912632Test

6

Prediction of Cyclosporin-Mediated Drug Interaction Using Physiologically Based Pharmacokinetic Model Characterizing Interplay of Drug Transporters and Enzymes

المؤلفون: Zexin Zhang, Zhongjian Wang, Yi-ting Yang, Li Liu, Xiaodong Liu, Ping Li

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 7023, p 7023 (2020)
Volume 21
Issue 19

مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Atorvastatin, physiologically based pharmacokinetic model, drug transporters, Pharmacology, 030226 pharmacology & pharmacy, Models, Biological, Catalysis, Article, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, the interplay of transporters and enzymes, medicine, Cytochrome P-450 CYP3A, Humans, Computer Simulation, Drug Interactions, Physical and Theoretical Chemistry, drug–drug interaction, Enzyme Inhibitors, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, Chemistry, Multidrug resistance-associated protein 2, Organic Chemistry, Transporter, Cerivastatin, Biological Transport, General Medicine, Drug interaction, Computer Science Applications, Intestines, lcsh:Biology (General), lcsh:QD1-999, Liver, 030220 oncology & carcinogenesis, Cyclosporine, pharmacokinetics, medicine.drug, Fluvastatin