التفاصيل البيبلوغرافية
| العنوان: |
Clinical Assessment of Plaque Removal Using a Novel Dentifrice Containing Cellulose Microfibrils. |
| المؤلفون: |
Labib, Mohamed E., Perazzo, Antonio, Manganaro, James, Tabani, Yacoob, Milleman, Kimberly R., Milleman, Jeffery L., Walsh, Laurence J. |
| المصدر: |
Dentistry (2304-6767); Jan2024, Vol. 12 Issue 1, p7, 10p |
| مصطلحات موضوعية: |
DENTIFRICES, CELLULOSE, MICROFIBRILS, DENTAL plaque |
| مستخلص: |
Dentifrice performance in the removal of dental plaque is influenced by the interactions of dentifrice components with tooth surfaces. This randomized controlled clinical study assessed the effectiveness and safety of a novel fluoride dentifrice formulation that included a micro-fibrillated cellulose network with entangled microcrystalline cellulose and silica particles (ProtegeraTM), and compared this to a positive control fluoride dentifrice (Crest Cavity Protection™). Whole mouth dental plaque levels in 82 healthy adults were measured after the first supervised use, and following a week of twice daily use at home. Overall, the test dentifrice was at least three times and up to four times more effective in whole-mouth plaque reductions, with a 38.6% reduction on first use, a 30.9% reduction at day 7, and a 41.6% reduction from day 1 to day 7, compared to reductions of 12.0%, 9.6% and 11.6%, respectively for the positive control, and up to seven times more effective in lingual plaque reductions, than the reference dentifrice (p < 0.001), with a 27.7% reduction on first use, a 22.3% reduction at day 7, and a 31.0% reduction from day 1 to day 7, compared to reductions of 4.4%, 2.2%, and 4.5%, respectively, for the positive control. No safety issues arose from the use of the test dentifrice. These results indicate that including micro-fibrillated cellulose enhances plaque removal effectiveness, without causing adverse changes to oral soft tissues. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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