Comparative Efficacy of Various Stents for Palliation in Patients with Malignant Extrahepatic Biliary Obstruction: A Systematic Review and Network Meta-Analysis
| العنوان: | Comparative Efficacy of Various Stents for Palliation in Patients with Malignant Extrahepatic Biliary Obstruction: A Systematic Review and Network Meta-Analysis |
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| المؤلفون: | Da Hae Park, Jung Hee Kim, Se Woo Park, Chan Hyuk Park, Eun Suk Jung, Jang Han Jung |
| المصدر: | Journal of Personalized Medicine Journal of Personalized Medicine, Vol 11, Iss 86, p 86 (2021) Volume 11 Issue 2 |
| بيانات النشر: | MDPI, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, metal stent, business.industry, medicine.medical_treatment, lcsh:R, Medicine (miscellaneous), Stent, lcsh:Medicine, Biliary Stenting, Lower risk, equipment and supplies, Article, Surgery, plastic stent, Relative risk, Meta-analysis, Occlusion, Medicine, malignant biliary obstruction, In patient, stent, cardiovascular diseases, business, Adverse effect, recurrent biliary obstruction |
| الوصف: | Although many studies have investigated the efficacy of stent placement for patients with malignant extrahepatic biliary obstruction, the clinical outcomes and adverse events of biliary stenting have not been comprehensively evaluated. We searched all relevant randomized-controlled trials that evaluated the comparative efficacy of biliary stents, including the plastic stents, uncovered self-expandable metal stents (SEMSs), and covered SEMSs in patients with malignant extrahepatic biliary obstructions. Twenty-one studies with 2326 patients were included. Both uncovered and covered SEMSs had a lower risk of recurrent biliary obstruction (RBO) compared to plastic stents (risk ratio (RR) (95% confidence interval [CI]): uncovered vs. plastic, 0.46 (0.35–0.62) covered vs. plastic, 0.46 (0.34–0.62)). A comparison of the groups using SEMSs revealed that tumor ingrowth was common in the uncovered SEMS group, while stent migration, tumor overgrowth, and occlusion by sludge were common in the covered SEMS group however, the overall risk of RBO did not differ between these groups (RR (95% CI): uncovered vs. covered: 1.02 (0.80–1.30)). Although the main causes of RBO vary across stents, RBO risk was similar between uncovered and covered SEMS groups. Both SEMSs have superior efficacy in terms of RBO compared to plastic stents. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2075-4426 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a383a132dcb08779ea959499257d488Test http://europepmc.org/articles/PMC7912345Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2a383a132dcb08779ea959499257d488 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20754426 |
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