دورية أكاديمية
Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain
| العنوان: | Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain |
|---|---|
| المؤلفون: | Leiva-Gea, I, Antúnez Fernández, Cristina, Cardona-Hernandez, Roque, Ferrer-Lozano, Marta, Bahíllo-Curieses, Pilar, Arroyo Diez, Francisco Javier, Clemente Leon, Maria |
| المساهمون: | Institut Català de la Salut, Leiva-Gea I Pediatric Endocrinology, Department of Pediatrics, Hospital Regional de Málaga, Málaga, Spain. Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain. Antúnez Fernández C Department of Pediatrics, Hospital Punta de Europa, Algeciras, Spain. Cardona-Hernandez R Division of Pediatric Endocrinology, Hospital Sant Joan de Déu, Passeig Barcelona, Spain. Ferrer Lozano M Pediatric Endocrinology, Department of Pediatrics, Hospital Universitario Miguel Servet, Zaragoza, Spain. Bahíllo-Curieses P Pediatric Endocrinology, Department of Pediatrics, Hospital Clínico Universitario de Valladolid, Valladolid, Spain. Arroyo-Díez J Pediatric Endocrinology, Department of Pediatrics, Hospital Universitario Materno Infantil de Badajoz, Badajoz, Spain. Clemente León M Unitat d’Endocrinologia Pediàtrica, Servei de Pediatria, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Centre for Biomedical Research on Rare Diseases (CIBERER), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain, Vall d'Hebron Barcelona Hospital Campus |
| المصدر: | Scientia |
| بيانات النشر: | MDPI |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Diabetis infantil, Diabetis - Diagnòstic, COVID-19 (Malaltia), DISEASES::Nutritional and Metabolic Diseases::Metabolic Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetic Ketoacidosis, HEALTH CARE::Environment and Public Health::Public Health::Epidemiologic Factors::Age Factors::Age of Onset, DISEASES::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections, ENFERMEDADES::enfermedades nutricionales y metabólicas::enfermedades metabólicas::enfermedades nutricionales y metabólicas::enfermedades metabólicas::trastornos del metabolismo de la glucosa::diabetes mellitus::cetoacidosis diabética, ATENCIÓN DE SALUD::ambiente y salud pública::salud pública::factores epidemiológicos::factores etarios::edad de comienzo, ENFERMEDADES::virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus |
| الوصف: | COVID-19; Aparició de la diabetis; Diabetis tipus 1 ; COVID-19; Aparición de diabetes; Diabetes tipo 1 ; COVID-19; Diabetes onset; Type 1diabetes ; Objective: To assess the impact of the COVID-19 pandemic and lockdown measures on the presenting characteristics (age at diagnosis, severity, monthly distribution) of newly diagnosed type 1 diabetes in Spanish children. Research Design and Methods: An ambispective observational multicenter study was conducted in nine Spanish tertiary-level hospitals between January 2015 and March 2021. Inclusion criteria: new cases of type 1 diabetes in children (0–14 years) recording age, sex, date of diagnosis, presence of diabetic ketoacidosis (DKA) at onset, and severity of DKA. Data were compared before and during the pandemic. Results: We registered 1444 new cases of type 1 diabetes in children: 1085 in the pre-pandemic period (2015–2019) and 359 during the pandemic (2020–March 2021). There was a significant increase in the group aged ≤4 years in the pandemic period (chi-squared = 10.986, df 2, p = 0.0041). In 2020–2021, cases of DKA increased significantly by 12% (95% CI: 7.2–20.4%), with a higher percentage of moderate and severe DKA, although this increase was not significant. In 2020, there was a sharp decrease in the number of cases in March, with a progressive increase from May through November, higher than in the same months of the period 2015–2019, highlighting the increase in the number of cases in June, September, and November. The first three months of 2021 showed a different trend to that observed both in the years 2015–2019 and in 2020, with a marked increase in the number of cases. Conclusions: A change in monthly distribution was described, with an increase in DKA at onset of type 1 diabetes. No differences were found in severity, although there were differences in the age distribution, with an increase in the number of cases in children under 4 years of age. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2077-0383 |
| العلاقة: | Journal of Clinical Medicine;11(15); https://doi.org/10.3390/jcm11154338Test; Leiva-Gea I, Antúnez Fernández C, Cardona-Hernandez R, Ferrer Lozano M, Bahíllo-Curieses P, et al. Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain. J Clin Med. 2022 Jul 26;11(15):4338.; https://hdl.handle.net/11351/8272Test; 000838883200001 |
| DOI: | 10.3390/jcm11154338 |
| الإتاحة: | https://doi.org/10.3390/jcm11154338Test https://hdl.handle.net/11351/8272Test |
| حقوق: | Attribution 4.0 International ; http://creativecommons.org/licenses/by/4.0Test/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.873B006 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20770383 |
|---|---|
| DOI: | 10.3390/jcm11154338 |