التفاصيل البيبلوغرافية
| العنوان: |
Observational study on the therapeutic management and economic burden of adult patients with moderate to severe plaque psoriasis in France - the POP study. |
| المؤلفون: |
Villani, A. P., Tsimaratos, N. Quiles, Crochard, A., Gherardi, A., Panes, A., Schmidt, A., Kollen, M. Hueber, Borget, I. |
| المصدر: |
Journal of Market Access & Health Policy; Dec2023, Vol. 11 Issue 1, p1-11, 11p |
| مصطلحات موضوعية: |
PSORIASIS, NATIONAL health insurance, ADULTS, SCIENTIFIC observation, MEDICAL care costs |
| مصطلحات جغرافية: |
FRANCE |
| مستخلص: |
Background: Data on the therapeutic management and healthcare cost of moderate to severe psoriasis in France are scarce. Objective: To assess the therapeutic management and economic burden of patients with moderate to severe psoriasis. Setting: This is a retrospective observational study on the Generalist Beneficiaries Sample of the National Health Data System. Patients and outcome measures:Adults with moderate to severe psoriasis (with a topical vitamin D derivative followed by systemic treatment or hospitalization for psoriasis) were included and followed-up from 1 January 2009 to 31 December 2018. Patients were matched to controls without psoriasis. Patients' characteristics and healthcare cost from the National Health Insurance's (NHI) perspective were described. Results: Overall, 1,848 and 5,544 adults were included in the psoriatic and control cohorts, respectively. The most frequent treatments were methotrexate (18.5% to 21.4% of patients by year), phototherapy (29.9% in 2010 down to 6.2% in 2018), and acitretin (25.9% in 2010 down to 8.6% in 2018). Overall, 19% of patients used biotherapies. The mean healthcare costs reimbursed by NHI was €5,365/psoriatic patient (including €2,685 potentially attributable to psoriasis), which was twice as high as in controls. In both cohorts, healthcare costs increased over time. Conclusion: Moderate to severe psoriasis healthcare costs are high. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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