Comprehensive Analysis of the Real Lifestyles of T1D Patients for the Purpose of Designing a Personalized Counselor for Prandial Insulin Dosing
| العنوان: | Comprehensive Analysis of the Real Lifestyles of T1D Patients for the Purpose of Designing a Personalized Counselor for Prandial Insulin Dosing |
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| المؤلفون: | Pavlina Pithova, Katerina Stechova, Petr Cikl, Lenka Lhotska, J. Hlubik |
| المصدر: | Nutrients Volume 11 Issue 5 Nutrients, Vol 11, Iss 5, p 1148 (2019) |
| بيانات النشر: | MDPI, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Blood Glucose, Male, obesity, Time Factors, endocrine system diseases, type 1 diabetes, medicine.medical_treatment, Saturated fat, Pilot Projects, Overweight, 0302 clinical medicine, Body Fat Measurement, Medicine, Insulin, Drug Dosage Calculations, 030212 general & internal medicine, prandial insulin bolus, Nutrition and Dietetics, digestive, oral, and skin physiology, Middle Aged, Postprandial Period, Mobile Applications, Postprandial, Treatment Outcome, Female, medicine.symptom, lcsh:Nutrition. Foods and food supply, Adult, medicine.medical_specialty, postprandial glycaemia, 030209 endocrinology & metabolism, lcsh:TX341-641, Proof of Concept Study, Article, 03 medical and health sciences, Carbohydrate counting, Young Adult, Insulin Infusion Systems, Internal medicine, Dietary Carbohydrates, overweight, Humans, Hypoglycemic Agents, Exercise, Life Style, Type 1 diabetes, business.industry, carbohydrate counting, Blood Glucose Self-Monitoring, Feeding Behavior, mobile application, medicine.disease, Obesity, Diabetes Mellitus, Type 1, business, diet, Energy Metabolism, Biomarkers, Cell Phone, Food Science |
| الوصف: | Post-prandial hyperglycemia is still a challenging issue in intensified insulin therapy. Data of 35 T1D patients during a four-week period were analyzed: RT-CGM (real time continuous glucose monitoring) record, insulin doses, diet (including meal photos), energy expenditure, and other relevant conditions. Patients made significant errors in carbohydrate counting (in 56% of cooked and 44% of noncooked meals), which resulted in inadequate insulin doses. Subsequently, a mobile application was programmed to provide individualized advice on prandial insulin dose. When using the application, a patient chooses only the type of categorized situation (e.g., meals with other relevant data) without carbohydrates counting. The application significantly improved postprandial glycemia as normoglycemia was reached in 95/105 testing sessions. Other important findings of the study include: A high intake of saturated fat (median: 162% of recommended intake) a low intake of fiber and vitamin C (median: 42% and 37%, respectively, of recommended intake) an increase in overweight/obesity status (according to body fat measurement), especially in women (median of body fat: 30%) and low physical activity (in 16/35 patients). The proposed individualized approach without carbohydrate counting may help reach postprandial normoglycemia but it is necessary to pay attention to the lifestyle habits of T1D patients too. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2072-6643 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b264af339e69643f705999b6ebb961Test http://europepmc.org/articles/PMC6567095Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....60b264af339e69643f705999b6ebb961 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20726643 |
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