نتائج البحث

1

Fluorescence Cross-Correlation Spectroscopy Yields True Affinity and Binding Kinetics of Plasmodium Lactate Transport Inhibitors

المؤلفون: Iga Jakobowska, Stefan Hannus, Björn Henke, Stefano Minguzzi, Nathan Hugo Epalle, Frank Becker, Eric Beitz, Kerrin Hansen

المساهمون: Iga Jakobowska, Frank Becker, Stefano Minguzzi, Kerrin Hansen, Björn Henke, Nathan Hugo Epalle, Eric Beitz, Stefan Hannus

المصدر: Pharmaceuticals
Volume 14
Issue 8
Pharmaceuticals, Vol 14, Iss 757, p 757 (2021)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f232c0a8a9f7f3eb1b2229a4791f29Test
http://europepmc.org/articles/PMC8399565Test

2

Investigating the Antifungal Mechanism of Action of Polygodial by Phenotypic Screening in Saccharomyces cerevisiae

المؤلفون: Josphat C. Matasyoh, Johannes L. Vrijdag, Joris Winderickx, Geert Callewaert, Elja Eskes, Patrick Van Dijck, Liesbeth Demuyser, Petra D'hooge, Walter Luyten, Purity N. Kipanga

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5756, p 5756 (2021)
Volume 22
Issue 11

مصطلحات موضوعية: 0301 basic medicine, Antifungal Agents, Mutant, V-ATPase, chemistry.chemical_compound, 0302 clinical medicine, Ca2+ signaling and Ca2+ homeostasis, Homeostasis, Biology (General), Spectroscopy, biology, General Medicine, Hydrogen-Ion Concentration, Computer Science Applications, Cell biology, Mitochondria, Nucleosomes, Chemistry, Vacuolar acidification, TORC1 signaling, Nucleosome mobilization, Sesquiterpenes, Signal Transduction, Vacuolar Proton-Translocating ATPases, Saccharomyces cerevisiae Proteins, QH301-705.5, Saccharomyces cerevisiae, Polygodial, Microbial Sensitivity Tests, Mechanistic Target of Rapamycin Complex 1, Catalysis, Article, Inorganic Chemistry, Mitochondrial Proteins, 03 medical and health sciences, Ribosomal protein, Drug Resistance, Fungal, ubiquitin, Physical and Theoretical Chemistry, Molecular Biology, QD1-999, haploid deletion mutant library, Organic Chemistry, Autophagy, biology.organism_classification, 030104 developmental biology, chemistry, Calcium, vacuolar pH, 030217 neurology & neurosurgery, antifungal

وصف الملف: Electronic; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da98ac47f868b157e818844c0feccb5cTest
https://lirias.kuleuven.be/handle/123456789/676156Test

3

Cancer Cells Shuttle Extracellular Vesicles Containing Oncogenic Mutant p53 Proteins to the Tumor Microenvironment

المؤلفون: Bibek Bhatta, Ishai Luz, Christian Krueger, David P. Lane, Fanny Xueting Teo, Tomer Cooks, Kanaga Sabapathy

المصدر: Cancers
Cancers, Vol 13, Iss 2985, p 2985 (2021)
Volume 13
Issue 12

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e3de266a6b2b2e66fffdf36606b403Test
http://europepmc.org/articles/PMC8232660Test

4

Brown Spiders’ Phospholipases-D with Potential Therapeutic Applications: Functional Assessment of Mutant Isoforms

المؤلفون: Andrea Senff-Ribeiro, Larissa Vuitika, Thaís Pereira da Silva, Fernando Jacomini de Castro, Silvio Sanches Veiga, Nayanne Louise Costacurta Polli, Raghuvir K. Arni, Marianna Boia-Ferreira, Bruno Cesar Antunes, João Carlos Minozzo, Fernando Hitomi Matsubara, Ricardo Barros Mariutti, Luiza Helena Gremski, Ana Carolina Martins Wille

المساهمون: Universidade Federal do Paraná (UFPR), Centro de Produção e Pesquisa de Imunobiológicos (CPPI), Universidade Estadual Paulista (Unesp), Universidade Estadual de Ponta Grossa (UEPG)

المصدر: Biomedicines
Volume 9
Issue 3
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Biomedicines, Vol 9, Iss 320, p 320 (2021)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1bd0128bce0c6d2880a4ae2a3f05c61Test
http://europepmc.org/articles/PMC8004160Test

5

Fatal Attraction: The Case of Toxic Soluble Dimers of Truncated PQBP-1 Mutants in X-Linked Intellectual Disability

المؤلفون: Yu Wai Chen, Shah Kamranur Rahman

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2240, p 2240 (2021)

مصطلحات موضوعية: 0301 basic medicine, X-linked intellectual disability, Protein Conformation, Mutant, IDP, Review, Protein aggregation, Oligomer, lcsh:Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Genes, X-Linked, Frameshift Mutation, lcsh:QH301-705.5, Spectroscopy, biology, Chemistry, aggregation, General Medicine, Renpenning syndrome, Computer Science Applications, DNA-Binding Proteins, Biochemistry, RNA splicing, RNA Splicing, Intrinsically disordered proteins, Catalysis, Inorganic Chemistry, WW domain, 03 medical and health sciences, oligomerisation, Intellectual Disability, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, XLID, Organic Chemistry, medicine.disease, intrinsically disordered protein, misfolding, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, biology.protein, dimerisation, Mutant Proteins, Fatal attraction, Protein Multimerization, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef1e3306de9bc1fae772f48bd3c359aTest
http://europepmc.org/articles/PMC7956452Test

6

Characterization of the Frmd7 Knock-Out Mice Generated by the EUCOMM/COMP Repository as a Model for Idiopathic Infantile Nystagmus (IIN)

المؤلفون: Diego Gomez-Nicola, Tutte Newall, Jay E. Self, Andrew J. Lotery, Ahmed Salman, Jennifer Scott, Helen Griffiths, Helena Lee, Samuel B. Hutton

المصدر: Genes
Volume 11
Issue 10
Genes, Vol 11, Iss 1157, p 1157 (2020)

مصطلحات موضوعية: Male, 0301 basic medicine, retina, lcsh:QH426-470, optokinetic nystagmus, Mutant, Gene Expression, Nystagmus, Biology, Article, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Electroretinography, Genetics, medicine, Animals, Nystagmus, Optokinetic, Alleles, Genetics (clinical), Mice, Knockout, Retina, FRMD7, Genetic Diseases, X-Linked, Retinal, Idiopathic Infantile Nystagmus, Optokinetic reflex, lcsh:Genetics, Cytoskeletal Proteins, Disease Models, Animal, Electrophysiology, Amacrine Cells, 030104 developmental biology, medicine.anatomical_structure, chemistry, Mutation, Knockout mouse, 030221 ophthalmology & optometry, Reflex, Female, medicine.symptom, Nystagmus, Congenital, Neuroscience, Tomography, Optical Coherence, nystagmus

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c730c83c63ad874cb4e2fe608c56617Test
https://ora.ox.ac.uk/objects/uuid:70c72494-580e-4ea6-b160-c08a85dd5c4dTest

7

De-palmitoylation of tissue factor regulates its activity, phosphorylation and cellular functions

المؤلفون: Sophie Featherby, Araci M. R. Rondon, John Greenman, Anthony Maraveyas, Camille Ettelaie, Henri H. Versteeg

المصدر: Cancers; Volume 13; Issue 15; Pages: 3837
Cancers
Cancers, Vol 13, Iss 3837, p 3837 (2021)
Cancers, 13(15). MDPI

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3ef75c28ce045bb651f246f946cb2aTest
https://hdl.handle.net/1887/3230135Test

8

Structural Insight into the Contributions of the N-Terminus and Key Active-Site Residues to the Catalytic Efficiency of Glutamine Synthetase 2

المؤلفون: Wen-Ting Chen, Hsien-Sheng Yin, Szu-Chin Ma, Wei-Cheng Chen, Hsin-Yu Yang, Yi-Zong Lee, Chih-Yu Lin

المصدر: Biomolecules
Biomolecules, Vol 10, Iss 1671, p 1671 (2020)
Volume 10
Issue 12

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Circular dichroism, crystal structure, Stereochemistry, Pentamer, Mutant, lcsh:QR1-502, Biochemistry, Zea mays, lcsh:Microbiology, Article, Biophysical Phenomena, Protein Structure, Secondary, 03 medical and health sciences, 0302 clinical medicine, Glutamate-Ammonia Ligase, Glutamine synthetase, enzyme kinetics, Catalytic Domain, Animals, Humans, Enzyme kinetics, Amino Acid Sequence, Protein Structure, Quaternary, Drosophila melanogaster, Molecular Biology, Protein secondary structure, biology, Chemistry, Active site, glutamine synthetase, Recombinant Proteins, circular dichroism, Glutamine, Kinetics, Protein Subunits, 030104 developmental biology, Structural Homology, Protein, biology.protein, Biocatalysis, Mutant Proteins, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac826bc8792a6ffb84e739aded1fffbcTest
http://europepmc.org/articles/PMC7764910Test

9

The Salt Sensitivity Induced by Disruption of Cell Wall-Associated Kinase 1 (SlWAK1) Tomato Gene Is Linked to Altered Osmotic and Metabolic Homeostasis

المؤلفون: Francisco B. Flores, Maria C. Bolarin, Fernando J. Yuste-Lisbona, Elisabeth Esch, Isabel Egea, Stéphanie Drevensek, Victoriano Meco, Fredy Barneche, Rafael Lozano, Ana Ortíz-Atienza, Wim H. Vriezen

المساهمون: Centro de Edafologia y Biologia aplicada del Segura (CEBAS - CSIC), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Centro de Investigación en Biotecnología Agroalimentaria, Universidad de Almería (UAL), Institut de biologie de l'ENS Paris (UMR 8197/1024) (IBENS), Département de Biologie - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de biologie de l'ENS Paris (IBENS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Département de Biologie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (17), pp.6308. ⟨10.3390/IJMS21176308⟩
riUAL. Repositorio Institucional de la Universidad de Almería
Universidad de Almería
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6308, p 6308 (2020)

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Osmosis, [SDV]Life Sciences [q-bio], Mutant, 01 natural sciences, Salt Stress, lcsh:Chemistry, Solanum lycopersicum, Cell Wall, Gene Expression Regulation, Plant, Homeostasis, lcsh:QH301-705.5, Spectroscopy, metabolites, Plant Proteins, 2. Zero hunger, Chlorosis, biology, Chemistry, food and beverages, General Medicine, Salt Tolerance, Sucrose transport, Computer Science Applications, Cell biology, ion stress, Osmotic shock, Article, Catalysis, Inorganic Chemistry, 03 medical and health sciences, insertional mutant, Physical and Theoretical Chemistry, Molecular Biology, Abiotic stress, Organic Chemistry, fungi, Wild type, Biotic stress, biology.organism_classification, fruit yield, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, osmotic stress, Solanum, 010606 plant biology & botany, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019f60e9ce03c1ba061035194ab88121Test
http://hdl.handle.net/10835/8416Test

10

Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma

المصدر: Cancers
Cancers, vol 13, iss 13
Volume 13
Issue 13
Cancers, Vol 13, Iss 3342, p 3342 (2021)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd904b891864a025cd7be9921554d878Test
http://europepmc.org/articles/PMC8268167Test

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